Cornelis MC, El - Sohemy A, Campos H. Genetic polymorphism of the adenosine A2A receptor is associated
with habitual caffeine consumption.
However,
with habitual caffeine consumption, the affectedness of caffeine is greatly reduced.
Genetic polymorphism of the adenosine A2A receptor is associated
with habitual caffeine consumption
Not exact matches
... Hence, unless additional evidence becomes available indicating cumulative total water deficits in individuals
with habitual intakes of significant amounts of
caffeine, caffeinated beverages appear to contribute to the daily total water intake similar to that contributed by noncaffeinated beverages.»
Because people develop tolerance to
caffeine fairly quickly
with habitual use,
caffeine intoxication is most likely to occur in those who consume
caffeine infrequently or who have recently increased their intake significantly.