Sentences with phrase «with high heritability»

Attention - deficit / hyperactivity disorder (ADHD) is a common psychiatric disorder among children and adolescents with high heritability.

In our study, an 18.3 % incidence of idiopathic epilepsy was found among related Irish wolfhounds with a high heritability of 0.87 for the trait.

Not exact matches

Despite high heritability estimates of 45 % in childhood and 80 % in adulthood, only a handful of genes had previously been associated with intelligence and for most of these genes the findings were not reliable.

If ADHD were a clear - cut disorder that was either present or not, researchers would expect to find a higher heritability in the group with more symptoms, says Levy.

Twin studies show a higher concordance of AD among monozygotic compared to dizygotic twins, with heritability estimates of 60 % to 80 %.

The greatest improvement, however, can be expected in breeds with low population, high heritability, and strong breed clubs concerned about genetic defects; likewise the greatest decline in joint quality can be expected in breeds experiencing the fastest growth in popularity and indiscriminate breeding.

The analyses importantly demonstrated a high degree of heritability, which indicate that, with the correct scheme, eradication of this highly unpleasant condition should be possible within a short time period.

Prepubertal onset has been associated with lower risk of recurrence16, 17; higher risk of bipolar disorder, suicide attempts, alcohol dependence, and conduct disorder17; and lower heritability.18, 19 Results from family studies have been inconsistent.

Rather fewer meet the diagnostic criteria for research, which for the oppositional defiant type of conduct disorder seen in younger children require at least four specific behaviours to be present.7 The early onset pattern — typically beginning at the age of 2 or 3 years — is associated with comorbid psychopathology such as hyperactivity and emotional problems, language disorders, neuropsychological deficits such as poor attention and lower IQ, high heritability, 8 and lifelong antisocial behaviour.9 In contrast, teenage onset antisocial behaviour is not associated with other disorders or neuropsychological deficits, is more environmentally determined than inherited, and tends not to persist into adulthood.9

Furthermore, the high heritability of CU traits and their association with more chronic and serious aggression and antisocial behaviour problems make them a strong candidate for the driving force behind the familial transmission of aggressive behaviour that Halperin et al. [38] argue is mediated, in part, by reduced central serotonin function.

In addition, given the high heritability of antisocial behaviour problems in the presence of high levels of CU traits, it was hypothesized that CU traits would be significantly associated with functional polymorphisms of the serotonin - system.