The study also found serum deficiencies in those same nutrients
with high homocysteine levels, which may be associated with hardening of the arteries, also predicted likeliness of developing AMD.
Not exact matches
As
with miscarriage, the evidence is conflicting on whether
high homocysteine levels cause other pregnancy problems such as:
The usual recommendation in women
with elevated
homocysteine levels is to take
high doses of folic acid and B vitamins to improve the body's metabolism of
homocysteine.
In addition, there has been some evidence that folic acid might reduce the risk of other birth defects as well, and that moms
with low folic acid might also have a
higher risk of miscarriage, placental abruption, and preterm delivery — possibly because of the relationship between low folic acid and
homocysteine levels.
Research studies demonstrate that
high intake of vitamin B6, vitamin B12 and folate is associated
with lower
homocysteine levels.
Patients
with inborn errors of
homocysteine metabolism have exceedingly
high levels of blood
homocysteine (up to 500 µM; normal 8 - 12 µM) and invariably suffer cardiovascular complications if left untreated.
Among the 50 trials, 30 were primary prevention trials (general populations, smokers and workers exposed to asbestos, patients
with oesophageal dysplasia, male physicians, patients
with non-melanoma skin cancer, postmenopausal women, patients undergoing chronic haemodialysis, patients
with end stage renal disease, ambulatory elderly women
with vitamin D insufficiency, patients
with chronic renal failure, older people
with femoral neck fractures, patients
with diabetes mellitus, elderly women
with a low serum 25 - hydroxyvitamin D concentration, health professionals, people
with a
high fasting plasma total
homocysteine concentration, or kidney transplant recipients), and 20 were secondary prevention trials (patients
with cardiovascular disease, coronary heart disease, acute myocardial infarction, unstable angina, transient ischaemic attack, stroke, angiographically proved coronary atherosclerosis, vascular disease, or aortic valve stenosis).
Researchers first began to suspect that
homocysteine plays a role in heart risk when they noticed that children
with extremely
high levels stemming from a rare genetic disorder also have
high rates of heart problems.
Doctors have speculated that folic acid may improve heart health, because people
with B - vitamin deficiencies often have
high blood levels of the amino acid
homocysteine, a marker of inflammation that has been linked to an increased risk of heart disease.
High level of
homocysteine is associated
with an increased risk of heart disease.
Several comprehensive reviews of available published scientific findings on the progression of Alzheimer's disease reveals that
high levels of the toxic amino acid
homocysteine as well as low folic and B12 levels in blood are associated
with an increase in the risk of developing Alzheimer's disease.
Since
high levels of
homocysteine are associated
with an increased risk for atherosclerosis, diabetic heart disease, heart attack, and stroke, it's a good idea to be sure that your diet contains plenty of vitamin B12 to help keep
homocysteine levels low (
homocysteine is also associated
with osteoporosis, and a recent study found that osteoporosis occurred more frequently among women whose vitamin B12 status was deficient or marginal compared
with those who had normal B12 status.)
Homocysteine is a dangerous molecule that is directly damaging to blood vessel walls, and
high levels of it are associated
with an increased risk of heart attack and stroke.
IGF1 levels does not necessarily means that you're gonna get cancer.IGF1 is a metabolic pathway for growth, yes growth in general from muscle tissue, bones, even organs BUT.There is a huge difference from ingecting into yourself, artificial IGF1 HGH etc and causing you body to secrete it naturall.When i say naturally i'm not talking about animal products (i am a vegan btw except some use of honey and bee pollen) animal product consumption is linked to a numerous deseases due to saturated fats, trans fats,
high concentrations of sulfuring aminos even heme iron http://www.ncbi.nlm.nih.gov/pubmed/23983135.Blaming soy protein (which btw has some great health benefits, general the soy bean) is at least wrong.Ok consuming every day 1 kg of soy probably is not good, as NOTHING is at very
high quantities.Nothing wrong
with natto, tempeh, tofu, soymilk, soybean, ans SPI.Asian people have been consuming soy for thousands of years without negative effects.Soy and especially SPI for people who are doing serious natural bodybuilding without use of AAS and artificial growth factors, and are also vegans believe me is a pain in the a $ $ and soy protein is maybe the ONLY type of protein that has sufficient ratios of amino acids, from bcaas to even sulfur aminos (but in normal levels not the dangerous levels linked to the
homocysteine rise in the blood).
Omnivores have
higher homocysteine levels than vegans that supplement
with B12.
High homocysteine levels have been associated
with an increased incidence of cardiovascular problems.
Patients
with hypothyroidism have significantly
higher plasma levels of
homocysteine (16).
HOWEVER, I've seen a couple of women who have the 1298 mutation
with higher levels of
homocysteine, so don't rule this out.
However, research also links
high levels of
homocysteine with raised blood pressure, suggesting that a diet containing plenty of folate may benefit blood pressure (10, 11).
Popeye got it right in eating spinach.Spinach is a good source of vitamins A and B folate which are essential nutrients in reducing
homocysteine levels.A study published in the journal «Neurology», experts said that 50 % of spinachpeople
with chronic fatigue were deficient in folate and consequently had
higher levels of
homocysteine.Spinach's folate is backed up by more than a dozen anti-inflammatory flavonoids.
People
with high amounts of
homocysteine in their blood are not healthy and have an increased chance of a heart attack.
Homocysteine is extremely unhealthy to have in
high levels and
high levels have been associated
with PCOS.
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While serum cholesterol levels provide an inaccurate indication of future heart disease, a
high level of a substance called
homocysteine in the blood has been positively correlated
with pathological buildup of plaque in the arteries and the tendency to form clots — a deadly combination.
Research has found that individuals
with the lowest levels of
homocysteine have about half the risk of developing Alzheimer's disease compared to those
with the
highest levels.
Have not really found that supplementing
with folate (not folic) helps, but a
high dose of TMG will lower
homocysteine and in turn LDL.
One early sign of B12 deficiency is elevated
homocysteine levels associated
with a
high concentration of histamine in the body.
People
with cardiovascular disease (especially elevated
homocysteine), a history of depression, migraine headaches, thyroid disorders, an autoimmune condition, ASD or are poor detoxifiers show a
higher incidence of this genetic mutation.
They are associated
with arterial plaque, neoplasia, tumors and a long list of metabolic imbalances.20 - 22
Homocysteine levels are
higher in most vegetarians because of inadequate dietary protein and B vitamins (especially B12) in general or excess soy in particular.23 - 26 Soy is marketed as a «perfect protein» because it contains all the essential amino acids, but «contains all» is not the same as contains optimum — and usable — levels and ratios.
When the body has normal levels of vitamin B12, it's able to counter the effects of a compound in the blood called
homocysteine, which at
high levels, is associated
with Alzheimer's disease and stroke, Hooshmand said.
Too much
homocysteine can damage blood vessel walls, and
high levels of it are associated
with increased risk of heart attack and stroke.
High levels of
homocysteine are associated
with an increased risk of heart disease.
People
with elevated
homocysteine levels have a much
higher risk of forming blood clots.
It was first suggested back in 1999 that elevated levels of
homocysteine in the blood are associated
with a
higher risk of cardiovascular disease40.
Individuals
with the MTHFR gene variation and
high homocysteine levels may also benefit from activated versions of folate, B6, and B12, such as methylated folate (also known as L -5-MTHF Folate, methylfolate, 5 - formyltetrahydrofolate or NatureFolate), Pyridoxyl -5-Phosphate (P5P), and methylcobalamin, respectively.
In a sample of 1,092 men and women without dementia followed for an average of 10 years, those
with higher plasma
homocysteine levels at baseline had a significantly
higher risk of developing Alzheimer's disease and other types of dementia.
A prospective study in 816 elderly men and women reported that those
with hyperhomocysteinemia (
homocysteine levels > 15 μmol / L) had a significantly
higher risk of developing Alzheimer's disease or dementia.