Sentences with phrase «with higher genetic risk»

The researchers found strong evidence that people with higher genetic risk for several mental disorders — including schizophrenia, and to a lesser extent bipolar and major depressive disorder — are also at higher genetic risk for developing PTSD after a traumatic event.

Their quality of life suffered too, as those with higher genetic risk missed work and school more often and were more often admitted to the hospital because of asthma.

Among the Dunedin study participants who developed asthma in childhood, those with higher genetic risk scores were also more likely to suffer with persistent asthma into adulthood.

Within each genetic risk category, the presence of lifestyle factors significantly altered the risk of coronary events to such an extent that following a favorable lifestyle could reduce the incidence of coronary events by 50 percent in those with the highest genetic risk scores.

A planned clinical trial in people with high genetic risk of developing Alzheimer's will put the amyloid hypothesis to the test yet again

Keeping fit, even if you're born with a high genetic risk for heart disease, still works to keep your heart healthy, according to a study led by researchers at the Stanford University School of Medicine.

Not exact matches

While GMOs are banned from foods certified organic (like MELT Organic), USDA enforcement on genetic testing is lacking for verifying non-GMO status with high risk ingredients (e.g., canola, corn, soy, alfalfa, sugar beets, zucchini, cotton, etc.) whose organic seed may have been contaminated by neighboring farms.

However, this study only included kids at high - risk for celiac (based on genetic markers or a first - degree relative with the disease), so it might not apply to the general population.

Results were similar in analyses of sleep patterns; among participants with some genetic risk of obesity, those who woke up frequently or slept more restlessly had higher BMIs than those who slept more efficiently.

(1) These regulatory thresholds reflect a decline in sperm quality with age and the greater likelihood of DNA mutations and higher risk of genetic abnormality in offspring.

The authors searched for genetic mutations that might explain the disproportionately high risk of SUDEP in people with poorly controlled focal epilepsy, which, by definition stems from a specific area of the brain.

«We believe that individuals born with this genetic mutation and who are later exposed to MAP through consuming contaminated milk or meat from infected cattle are at a higher risk of developing rheumatoid arthritis,» Naser said.

The group has also shown that in humans, genetic variants of the Oprl1 gene are associated with higher risk of developing the disorder after exposure to trauma.

Led by Brenda Penninx, PhD, of the VU University Medical Center in Amsterdam, the Netherlands, the study found that patients with an early age at onset and higher symptom severity have an increased genetic risk for MDD, bipolar disorder and schizophrenia.

Women with a family history of two or more immediate family members (mother, sister, daughter) with breast or ovarian cancer or with a positive genetic test for mutations in the BRCA1 or BRCA2 genes may be advised to consider having both breasts removed, because they are at high risk of a new cancer developing in the other breast.

«Depressed patients with earlier and more severe symptoms have high genetic risk for major psychiatric disorders.»

The National Institutes of Health - funded study, published July 2 in the New England Journal of Medicine, also found that participants in Sweden had higher rates of celiac disease than participants in the United States, Finland and Germany, even with the same genetic risks.

Using an independent group of 1602 MDD patients and 1390 control participants from the RADIANT - UK study, the researchers also replicated their finding that patients with a high number of DSM symptoms have increased genetic risk for schizophrenia.

Should the results be confirmed by further studies, it is possible that patients with certain genetic changes in BRCA1 could be identified as being at higher risk of breast and ovarian cancer.

«For the future,» she added, «might we match donors and recipients based on genetic factors, or consider fertility preservation for women with a high risk of premature ovarian failure?»

Those at higher genetic risk developed asthma earlier in life than did those with lower risk.

«Genetic risk factors may be more fully expressed in environments with low parental monitoring and high alcohol availability, and the presence of friends, particularly close friends, who drink.»

A tool intended to detect signs of autism in high - risk infants can be used to help identify and treat patients with tuberous sclerosis complex (TSC), a genetic disorder, who most need early intervention.

«This study demonstrates that a high - risk social environment can overwhelm the protective effect of a genetic variant associated with alcohol - related behaviors,» said Emily Olfson, an MD - PhD student at Washington University School of Medicine as well as first author of this study.

Male teens who experiment with cannabis before age 16, and have a high genetic risk for schizophrenia, show a different brain development trajectory than low risk peers who use cannabis.

Each of the genetic variants studied by the researchers is a single - nucleotide polymorphism, or SNP — a site at which the DNA code is altered by a single «letter» or nucleotide in some individuals, and where one «letter» is more commonly found in individuals with higher fracture risk.

The researchers found that, when the «genetic risk score» was used with the GFRC, the correct classification of individuals as high or low fracture risk was increased by 12 % over and above that of the traditional clinical risk factors, which together correctly classify up to 80 % of the studied individuals into high and low risk categories.

As Rand says, «A much higher level of study with more subjects in the cohort would be required before concluding that a genotype [an individual's particular genetic variation] is a risk factor.»

«Increased meat consumption, especially when cooked at high temperatures, linked to elevated kidney cancer risk: Individuals with certain genetic variations more vulnerable to dietary risk.»

Our study, along with prior studies, supports the notion that «cognitive reserve» resulting from early - life and lifelong education and cognitive stimulation may be a potent strategy for the primary prevention of dementia in both high - and low - income countries around the world.21 However, it should be noted that the relationships among education, brain biology, and cognitive function are complex and likely multidirectional; for instance, a number of recent population - based studies have shown genetic links with level of educational attainment, 22,23 and with the risk for cognitive decline in later life.24 Higher levels of educational attainment are also associated with health behaviors (eg, physical activity, diet, and smoking), more cognitively - complex occupations, and better access to health care, all of which may play a role in decreasing lifetime dementia risk.

The current study focused on the genetic pathways that cause a rare genetic disease called Li - Fraumeni Syndrome or LFS, which comes with high risk for many cancers in affected families.

We predicted that MP's behavioral effects in marijuana abusers would be attenuated, consistent with preclinical findings (30), and that decreased DA reactivity in ventral striatum would be associated with higher scores in negative emotionality (neuroticism), which mediates genetic risk for marijuana dependence (31), and with addiction severity.

«Our research finds that a set of genetic risks identified from UK patients with a clinical diagnosis of childhood ADHD also predicted higher levels of developmental difficulties in children from a UK population cohort, the ALSPAC,» said Thapar.

Testing for these variants combined with all 21 previously identified using genetic sequencing identified men with a 10-fold higher risk of testicular cancer than the population average.

This evidence suggests that people with high - genetic risk for schizophrenia - spectrum disorders receive a protective effect of the healthy family environment of 86 % decrease in risk.

Adoptees with high - genetic risk for schizophrenia - spectrum disorders (see below) have been found to be more sensitive to environmental effects than adoptees with low - genetic risk for the disease.

The Clinical Cancer Genetics Program coordinates genetic testing and high - risk cancer surveillance for individuals and their families with hereditary cancer syndromes.

Examples of higher risk would include women who carry a strong genetic predisposition to breast cancer, such as carriers of a BRCA1 or BRCA2 mutation, or woman with dense breasts (making mammography difficult) who have a first degree relative with breast cancer.

This means that adoptees with high - genetic risk for schizophrenia - related disorders did not have any measurable impact on parental communication and care giving skills, or on the functioning of the rest of the family, according to the OPAS rating system that was used to evaluate the families in the study.

Native American ancestry is associated with a lower asthma risk, but African ancestry is associated with a higher risk, according to the largest - ever study of how genetic variation influences asthma risk in Latinos, in whom both African and Native American ancestry is common.

We envision a day when all elementary students are exposed to principles of genetics and disease risk; when all high school students have the opportunity to do hands - on experiments with DNA; and when all families have access to genetic information they need to make informed health care choices.

The study reports a genetic variant in the gene MYH6 that is associated with high risk of sick sinus syndrome (SSS) in Icelanders.

The information suggests the protective effect of being reared in a healthy adoptive family, with the risk for these high - genetic - risk adoptees developing schizophrenia in healthy families at 5.8 % compared with 36.8 % for those reared in «dysfunctional» families.

A more recent interest concerns infants and children at high risk for developing autism (such as those with an older sibling with autism or who have a particular genetic variance).

Anette - Gabriele Ziegler and colleagues report their novel genetic risk score for identifying infants with a high risk of developing type 1 diabetes.

Genetic variants in highly penetrant genes (BRCA1 and BRCA2) confer a significantly higher risk of being diagnosed with breast cancer, while changes in other genes have a more moderate impact on risk.

The distribution of disease genes confirms genetic heterogeneity and opens new perspectives in genetic testing in patients with LVNC and their relatives at high risk of inheriting the cardiomyopathy.

Listen to a podcast on the genetic syndromes associated with a higher risk of colon cancer.

Moreover, risk factors may be different for different individuals - while one person may develop schizophrenia due largely to a strong family history of mental illness (e.g. a high level of genetic risk), someone else with much less genetic vulnerability may also develop the disease due to a more significant combination of prepregnancy factors, pregnancy stress, other prenatal factors, social stress, family stress or environmental factors that they experience during their childhood, teen or early adult years.

Researchers first began to suspect that homocysteine plays a role in heart risk when they noticed that children with extremely high levels stemming from a rare genetic disorder also have high rates of heart problems.