The size difference between tumor and healthy circulating DNA was initially discovered in animal tumor models created by inducing
tumors with human cancer cells.
Treatment for pets with cancer has many
similarities with human cancer treatment, now more so that new drug therapies are available for animal patients.
The team selected possible leads from the intersection of more than 20,000 p53 binding sites in the human genome, 10 million inherited genetic variations genotyped in the 1000 Genomes Project, and 62,000 genetic variations
associated with human cancers identified in genome - wide association studies (GWAS).
In addition, they injected
mice with human cancer cells and found that the tumors grown in mice could be inhibited with PD173074.
They also compared the DFT
cancer with a human cancer and found that anti-cancer drugs for people, intended to stop the growth of molecules called receptor tyrosine kinases, worked well and stopped the growth of devil cancer cells growing in the lab.
Today, one of the main focuses in Dey's lab is
working with human cancer cell lines to study oxygen - sensing metallo - enzymes.
Instead, I was more interested in asking broader questions, involving the role of animal protein based foods in their
association with human cancer, as well as to study the comparative associations of aflatoxin consumption and protein consumption in humans — this was the China Study.
Going beyond the veterinary profession, the Animal Cancer Center has an international reputation for its
collaboration with human cancer institutions such as the Mayo Clinic, the National Cancer Institute and the M.D. Anderson Cancer Center.
Just
like with human cancers time is of the essence for making decisions — our resource library will help you find information and experts quickly