Sentences with phrase «with human leukocyte»
Velimogene aliplasmid (Allovectin - 7), a plasmid / lipid complex with human leukocyte antigen (HLA)- B7 and β2 microglobulin DNA encoding sequences, was granted orphan drug designation by the FDA back in 1999.
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The treatment of renal cell carcinoma with human leukocyte alpha - interferon.
The second cohort of 140 patients with human leukocyte antigen - matched unrelated donor transplants completed enrollment in November 2017, with data expected from this randomized double - blind arm of the study in the next six months.
Not exact matches
Most of the leukocytes in human milk are killed with freezing anyway.
In a new research report published in the June 2014 issue of the Journal of Leukocyte Biology, researchers show that in individuals with asthma, statins significantly reduce the in vitro inflammatory response of human monocytes to rhinovirus (RV), the cause of the common cold.
On the other hand patients with DRB1 * 04:01 have a better clinical outcome in the short - and long - term suggesting that human leukocyte antigen (HLA) analysis and screening for SLA / LP antibodies should be integrated in the clinical routine for AIH diagnosis.
Most genes known to be associated with type 1 diabetes — including those currently considered the top two high - risk genes, which are the ones TEDDY screens for — are classified as human leukocyte antigen, or HLA genes.
«Our results show that, in an era in which high - resolution molecular typing for class I and class II HLA [human leukocyte antigen] loci has significantly improved the clinical outcome of unrelated donor HSCT by decreasing the risk of immunological complications, lowering the ATLG dose to 15 mg / kg did not affect the time to engraftment and, more importantly, the incidence of acute or chronic GVHD [graft - vs - host disease], and was associated with an improved probability of event - free survival, mainly due to a reduced risk of nonrelapse mortality,» wrote Franco Locatelli, MD, of the department of oncoematologia pediatrica, IRCCS Ospedale «Bambino Gesù» in Rome, and colleagues.
Patients receive one of two types of stem cell - based transplants: autologous, in which a patient donates and receives back his / her own stem cells; or allogeneic, in which bone marrow - derived stem cells come from a related or unrelated donor whose human leukocyte antigens (HLA) are genetically matched with those of a patient.
Primary sclerosing cholangitis (PSC) is strongly associated with several human leukocyte antigen (HLA) haplotypes.
The strongest genetic association with celiac disease — Human Leukocyte Antigen — is only responsible for 40 % of the risk, leaving us to suspect that there is likely an interplay of genetic and environmental variables that is more complex than just the activation of one in - born vulnerability.
Currently there are several known genes associated with Hashimoto's thyroiditis: cytotoxic T - lymphocyte associated antigen 4 (CTLA - 4), human leukocyte antigens (HLA), protein tyrosine phosphatase 22 (PTPN22) and thyroglobulin receptor gene.