Sentences with phrase «with human microbiota»

Kristen Earle, Gabriel Billings, KC Huang and Justin Sonnenburg, of Stanford University's School of Medicine, Department of Microbiology and Immunology, took second place with this photo of a mouse colon colonized with human microbiota, seen at 63x.

Not exact matches

How do the microbes within cheese interact with the natural microbiota of the human gut and can cheese be used to assist in maintaining a healthy gut microbiota?

Using a «gnotobiotic mouse model» — where mice were «colonized with a synthetic human gut microbiota composed of fully sequenced commensal bacteria» — Desai et al reported on the effects of different diets with different fibre content.

In collaboration with Synchrotron Oxford, the University of East Anglia and the University of California, the researchers, using a commonly - found member of human gut microbiota called Ruminococcus gnavus as a model organism identified carbohydrate binding modules with the ability to bind to mucus.

Over 100 different oligosaccharides have been identified in the human colon, and recent research has shown that variations in the oligosaccharides within the mucus are associated with variations in the composition of the gut microbiota.

«Alterations in the gut microbiota are associated with obesity and the metabolic syndrome in both humans and rodents,» Shulman noted.

The Wyss team believes the ability of the human gut - on - a-chip to culture the microbiome with human gut cells also holds promise for the field of precision medicine, where a patient's own cells and gut microbiota could one day be cultured inside a gut - on - a-chip for testing different therapies and identifying an individualized treatment strategy.

Kilner adds that there are potential parallels with the way the human immune system interacts with the gut microbiota: «The language in this field is now more about management than warfare.»

In addition, cohousing coprophagic mice harboring transplanted microbiota from discordant pairs provides an opportunity to determine which bacterial taxa invade the gut communities of cage mates, how invasion correlates with host phenotypes, and how invasion and microbial niche are affected by human diets.

The goal of the study was to explore whether fecal microbiota from human IBS patients with diarrhea has the ability to influence gut and brain function in recipient mice.

«It's increasingly clear that our gut bacteria, or microbiota, can communicate with the human brain,» said Kathy Magnusson, a professor in the OSU College of Veterinary Medicine and principal investigator with the Linus Pauling Institute.

The work «represents a significant step in understanding human microbiota coevolutionary history,» says Justin Sonnenburg of Stanford University in Palo Alto, California, who was not involved with the research.

People with diets high in fat, for example, have a different microbiota than do vegans, though in humans it is far more difficult to identify a core microbiota.

While a core microbiota of the same bacteria was present in all areas of the mock - up spacecraft, the authors noticed specific bacterial signatures for each individual area, or module, indicating that — much like in other indoor environments — microbial presence is associated with human presence as well as the type of activity that an area is used for.

Investigating mouse models for biological for research The congress aims to promote the International Mouse Phenotyping Consortium (IMPC) mouse lines, importance of mouse phenotyping & clinical and drug discovery collaboration, to present progresses performed by IMPC with regards CRISPR editing genome, rare diseases, microbiota and ageing pipeline, as well as illustration of examples of scientific projects about «Animal models for human diseases» and recent developments in mouse models phenotyping imaging.

BIOASTER conducts innovative collaborative research, with and for public and private partners in the four major application fields of microbiology including human and veterinary infectious diseases: vaccines, antimicrobials, diagnosis and microbiota.

Of special note today: gut microbiota species expressing orthologs of human Ro60 might be involved in triggering and sustaining chronic autoimmunity in lupus; The portal vein blood microbiome in patients with liver cirrhosis; A randomized clinical study suggests dietary promotion of short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plant

Spurred by this finding, Littman's team examined the gut microbiota in patients with rheumatoid arthritis, a debilitating autoimmune disease, and found a much higher proportion of patients than healthy individuals who harbored the human intestinal bacterium Prevotella copri.

A few interesting articles in early life human microbiome, plus: A comparison between Staphylococcus epidermidis commensal and pathogenic lineages from the skin of healthy individuals living in North American and India; A new tool to reconstruct microbial genome - scale metabolic models (GSMMs) from their genome sequence; The seasonal changes in Amazon rainforest soil microbiome are associated with changes in the canopy; A specific class of chemicals secreted by birds modulates their feather microbiome; chronic stress alters gut microbiota and triggers a specific immune response in a mouse model of colitis; and evidence that the short chain fatty acids profile in the gut reflects the impact of dietary fibre on the microbiome using the PolyFermS continuous intestinal fermentation model.

The congress aims to promote the International Mouse Phenotyping Consortium (IMPC) mouse lines, importance of mouse phenotyping & clinical and drug discovery collaboration, to present progresses performed by IMPC with regards CRISPR editing genome, rare diseases, microbiota and ageing pipeline, as well as illustration of examples of scientific projects about «Animal models for human diseases» and recent developments in mouse models phenotyping imaging.

These continually expanding resources enable experimental investigation of the human gut microbiota, validation of hypotheses made with sequence - based analyses, and phenotypic characterisation of its constituent microbes.

Conclusions: In an analysis of peripheral blood mononuclear cells and intestinal tissues from patients with inflammatory bowel diseases vs controls, we found that reactivity to intestinal bacteria is a normal property of the human CD4 + T - cell repertoire, and does not necessarily indicate disrupted interactions between immune cells and the commensal microbiota.

To do this, they colonized the intestines of germ - free mice with a synthetic human gut microbiota and exposed the mice to either a plant fiber - free diet or a plant fiber - rich diet.

How do the microbes within cheese interact with the natural microbiota of the human gut and can cheese be used to assist in maintaining a healthy gut microbiota?

«The results of this study indicate that type 2 diabetes in humans is associated with compositional changes in intestinal microbiota.»

The NIH Common Fund Human Microbiome Project (HMP) was established with the mission of generating research resources enabling comprehensive characterization of the human microbiota and analysis of their role in human health and disHuman Microbiome Project (HMP) was established with the mission of generating research resources enabling comprehensive characterization of the human microbiota and analysis of their role in human health and dishuman microbiota and analysis of their role in human health and dishuman health and disease.

Rodent studies have provided compelling insights; however, they have countless shortcomings as a reflection of human microbiota, human dietary patterns, and the ultimate intertwining of these variables with complex mental health disorders.

While not altering the overall structure of the human colonic microbiota, [rifaximin] increased bifidobacteria and led to variation of metabolic profiles associated with potential beneficial effects on the host.

The delicate balance between the human microbiome and the development of psychopathologies is particularly interesting given the ease with which the microbiome can be altered by external factors, such as diet, 23 exposure to antimicrobials24, 25 or disrupted sleep patterns.26 For example, a link between antibiotic exposure and altered brain function is well evidenced by the psychiatric side - effects of antibiotics, which range from anxiety and panic to major depression, psychosis and delirium.1 A recent large population study reported that treatment with a single antibiotic course was associated with an increased risk for depression and anxiety, rising with multiple exposures.27 Bercik et al. 28 showed that oral administration of non-absorbable antimicrobials transiently altered the composition of the gut microbiota in adult mice and increased exploratory behaviour and hippocampal expression of brain - derived neurotrophic factor (BDNF), while intraperitoneal administration had no effect on behaviour.

Here is a comprehensive list with various potential prebiotics, and the results of the research: Dietary modulation of the human colonic microbiota.

Artificial sweeteners have been shown to cause glucose intolerance in mice by altering gut microbiota and are associated with dysbiosis and glucose intolerance in humans.