To sort out the sequence of events
with human samples we will need longitudinal data on DNA methylation from birth and physical aggression from infancy onwards.
The ideal candidate for the position needs to be a highly skilled, well qualified person with a very responsible attitude towards work, since the position deals
with human samples.
Results obtained
with human samples will be substantiated with experiments in mouse models, including models based on genetically modified mice.
Studies in mouse models will permit extension of the human study to parameters that can not be assessed
with human samples, and enable selective analyses of antigen - specific T and B cells.
In addition, Dr. Klengel is investigating the epigenetic effects of stress and trauma exposure, exploring animal models in combination
with human samples.
«I hope that kind of work can be done in the future, but it's very difficult to do
with human samples.»
Not exact matches
But you won't hear it in what the experts tell you about Gadamer's greatness» for instance (to
sample recent tributes), that Gadamer has revealed «the structure of hermeneutic understanding» and «described the way in which
human beings come to terms
with themselves.»
Thus Wimberley and his associates have found in the 1970s, among a large if not absolutely representative
sample of North Carolinians, 74 percent agreement
with the statement: «
Human rights come from God and not merely from laws.»
In 2007, researchers published the first randomized, controlled study of the effect of being raised in an orphanage; that study, and subsequent research on the same
sample of Romanian orphans, found that compared
with babies placed
with a foster family, those who were sent to institutions had lower IQs, slower physical growth, problems
with human attachment and differences in functioning in brain areas related to emotional development.
The team compared the purchased
samples with their own preparations of
human milk diluted
with cow's milk to approximate the amount of contamination required in order to test positive for bovine DNA.
All purchased
samples did contain
human milk, but 11 also contained bovine DNA, 10 of which had results consistent
with more than minor, accidental contamination
with cow's milk.
One of the three major classes of immunoglobulin occurring in
human colostrum and milk, secretory IgA, has been found in significantly higher concentrations in the milk of mothers of preterm infants compared
with milk from mothers of term infants.3Skin - to - skin contact between mothers and preterm infants in this
sample may have promoted maternal production of protective antibodies specific to the nosocomial flora of the NICU.9 The provision of
human milk may enable preterm, VLBW infants to compensate for their inherently immature immune status.
The team also tested
human milk
samples from subjects
with mastitis, an infection of the breast tissue that causes pain and inflammation.
There are only a few instances of the polymer being assayed in the milk of women
with implants; the concentrations are not elevated over control
samples.20 There is no evidence at the present time that this polymer is directly toxic to
human tissues; however, concern also exists that toxicity may be mediated through an immunologic mechanism.
Researchers in United States found that 10 % of its
human milk
samples were adulterated
with cow's milk.
With humans, of course, the afterbirth and placenta are collected and
sampled...
In response to a recent
sampling event held at Orchard Park Middle School by
HUMAN operator partners NFL player Jon Corto and his wife, Jen, reporter and doctor Peter Ostrow said of
HUMAN's machines: ``... reading that LCD screen may encourage the kids to start reading labels, then they'll realize that the snacks they enjoy don't have to be loaded
with fats, processed foods, and sugar.
This may be to do
with interviewer effect,
with respondents being more willing to admit supporting a minor party in an online poll than to a
human interviewer, or may be something to do
with sampling.
The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in
human embryonic kidney cells, brain cell
samples and neurons derived from the stem cells of healthy people and those
with spinal muscular atrophy type I and II.
To establish the relevance of their findings, the team tested blood
samples from healthy
humans, as well as those
with a variety of inflammatory bowel diseases, including Crohn's.
Higham's team collected and radiocarbon - dated about 20
samples of artifacts and animal bones
with cut marks, which presumably were discarded by ancient
humans.
Researchers had never managed the feat on such ancient
human DNA; even younger
samples are often unreadable because they are riddled
with bacteria and other contaminants.
What's more, an ointment containing the peptide effectively treated wounds infected
with methicillin - resistant Staphylococcus aureus (MRSA) and the increasingly common hospital infection bacterium Acinetobacter baumannii in mice and on laboratory
samples of
human skin.
Larger biomarker signatures can be detected
with technology from CDI Laboratories, which offers microarrays of functional
human proteins (over 20,000 on a single array) to test the antibodies present in
human liquid biopsy
samples, such as blood, serum, plasma, CSF, or tissue lysates.
In cancer research, our goal is to be able to start
with a
sample of
human tissue, extract many cells of interest, and perform genetic analysis upon each of them separately.
The next step will be to gather more ancient
samples from before and after a major environmental change — the end of a glaciation, for example, or the arrival of
humans in the New World — to see whether any epigenetic changes correlate
with the environmental transition.
These techniques include:
human tissue created by reprogramming cells from people
with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where
human tissue
samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in
humans, safely and
with unsurpassed accuracy.
In times when a simple cheek swab mailed off
with a check can produce a
human DNA report listing thousands of ancestors, a
sample identification would seem a simple task.
«We've been through an obsession
with the weird and wonderful,
sampling volcanic springs, subterranean frozen lakes and nuclear reactors and now we're obsessed
with the microbiome and its role in
human health.
Last year, Szyf and researchers from Yale University published another study of
human blood
samples, comparing 14 children raised in Russian orphanages
with 14 other Russian children raised by their biological parents.
Testing
human samples, the team documented higher expression of RORα in skin Tregs compared
with those in blood, similar to mice.
In one test, 120 chickens were randomly selected from the 1,006 - bird
sample and placed one by one in a box
with a
human «predator» sitting visibly nearby.
We will develop multiplexed assays that will allow us to measure multiple proteins at a time in
human samples, thus increasing the speed
with which we can test candidate biomarkers.
But that study extracted ancient DNA from liver and intestinal
samples using a method susceptible to contamination
with modern
human and bacterial DNA, Drosou's team argues.
To that end, in collaboration
with the University of Zurich and MD Anderson Cancer Center, the researchers tested melanoma tumor
samples from
human patients undergoing treatment
with the same targeted therapies.
«The findings reported are derived from an artificial in vitro experimental system and do not appear to be consistent
with the data obtained by two independent groups utilising
samples from the
human clinical trials of the actual Merck Ad5 HIV vaccine.»
The team's data revealed that the mtDNA was like that of modern
humans and different from that of Neandertals, but critics argued that the
samples may have been contaminated
with modern
human DNA when an undetermined number of people handled the fossils.
In the new study, to test whether the same observation was true in
humans, Dr. Rostami and colleagues tested blood
samples of patients
with MS who had not yet received therapy, and those currently being treated
with INF - β, a commonly used therapy.
«Despite the relatively low
sample size of frozen products in our study, it is clear that commercial RMBDs may be contaminated
with a variety of zoonotic bacterial and parasitic pathogens that may be a possible source of bacterial infections in pet animals and if transmitted pose a risk for
human beings,» say the researchers.
On the other hand, the first
sampling site
with little
human activity should have had a higher biodiversity level.
The most contaminated
samples came from areas
with the highest
human population density, suggesting that cities were an important source of the lint.
In this instance, Cohen started
with human stool
samples in his hunt for gut bacteria
with DNA he could engineer.
Researchers have used radioimmunotherapy (RIT) to destroy remaining
human immunodeficiency virus (HIV)- infected cells in the blood
samples of patients treated
with antiretroviral therapy, offering the promise of a strategy for curing HIV infection.
They also found elevated granzyme A levels in blood
samples taken from non-
human primates infected
with chikungunya, as well as from
human chikungunya patients.
Li's team studied
samples of a fruit - fly derived version of Rumi in complex
with a Notch «surrogate» - a
human protein
with a Notch - like fold - that were provided by Haltiwanger.
When the team assessed FAL1 expression in
human ovarian cancer
samples, they found that high FAL1 expression tended to correlate
with poor clinical prognosis.
With this model, called heuristic training,
humans provide direct instructions that are used to pre-classify training
samples rather than a set of fixed examples.
They analyzed these
samples along
with hair
samples from 76 living
humans of European American and African descent.
ARM will demonstrate advanced, high - power, high - throughput solar electric propulsion; advanced autonomous high - speed proximity operations at a low - gravity planetary body; controlled touchdown and liftoff
with a multi-ton mass from a low - gravity planetary body, astronaut spacewalk activities for
sample selection, extraction, containment and return; and mission operations of integrated robotic and crewed vehicle stack — all key components of future in - space operations for
human missions to Mars.
He and Firpo have banked
human samples of IPMN for many years and shared some
with Hebrok for his research.