The narrow selectivity filter is only 12 angstroms long, whereas the remainder of the pore is wider and lined
with hydrophobic amino acids.
Not exact matches
The protein structure of the hard keratins such as wool is predominately
hydrophobic amino acids coupled
with a high lipid percentage lending a waterproof characteristic to the wool fiber.
The C - terminal end of the cytoplasmic tail of gp41, measuring 105
amino acid residues, was tightly associated to the membrane and had three alpha - helixes
with portions that were
hydrophobic and portions that were hydrophilic.
The results suggested that the tertiary amine groups bind to D97 on TM2 and E32 in the
amino terminus of CXCR4 through hydrogen bonds while aromatic residues Y45, W94, H113 and Y255 establish
hydrophobic interactions
with the aromatic counterpart of identified compounds.
Here, we use resurrected Precambrian proteins as scaffolds for protein engineering and demonstrate that a new active site can be generated through a single
hydrophobic - to - ionizable
amino acid replacement that generates a partially buried group
with perturbed physico - chemical properties.
Both cysteine and methionine are nonpolar as well as
hydrophobic,
with methionine being extremely
hydrophobic as far as
amino acids go.