However, attempted clinical management includes treatment
with hydroxyurea and dexamethasone.
Peterson ME, Randolph JF: Diagnosis of canine primary polycythemia and management
with hydroxyurea.
Not exact matches
Patients treated
with a drug called
hydroxyurea produce «healthier» red cells, suffer fewer painful attacks and need fewer transfusions, they say.
How
hydroxyurea works is not clear, although researchers know that it interferes
with the working of DNA.
«This is because while both cell types show
hydroxyurea - induced gene expression, collision
with replication occurs differentially because replication forks have progressed to different extent in these cells,» said Feng.
Examining the characteristics and beliefs of
hydroxyurea users and nonusers among adults
with sickle cell disease.
«A clinically meaningful fetal hemoglobin threshold for children
with sickle cell anemia during
hydroxyurea therapy.»