Sentences with phrase «with hypoxia»

Raising a child with a hypoxia - related birth injury (such as hypoxic - ischemic encephalopathy) can cost a small fortune.

Then again, the jellyfish are doing better with the heat and salinity where the rivers along coastlines are beginning to dry up, and they don't have quite as much trouble as fish with hypoxia — depending upon how bad it gets.

Melissa Ilardo, who was a graduate student at the University of Copenhagen when she did the work, sought to understand whether the Bajau had evolved their own strategies to cope with hypoxia while swimming.

ERK1 / 2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia - induced downregulation of ERalpha: a combination therapy potentially targeting hypoxic and dormant tumor cells

Based on his team's earlier work, Mootha wasn't surprised that the mice treated with hypoxia lived longer.

Of the 1035 genes that did not change with hypoxia, the expression of 36 genes was significantly changed after recovery.

Our results confirmed and extended previous observations that genes associated with hypoxia (specifically VEGF, Flk - 1, and EPO) are indeed elevated following hypoxia in the retina.

«This research will help prepare astronauts for spaceflight and it improves our understanding of how muscles respond to long periods of inactivity in association with hypoxia.

Not exact matches

Homebirth is expected to cause a delay in diagnosis, delivery and / or transfer following an acute intrapartum event with rapidly developing hypoxia, acidosis and asphyxia.

He isn't afraid of the baby dying or having brain damage from hypoxia or ending up with paralysis from a prolonged and damaging labor and delivery.

But, as the mother of two children who have learning disabilities — my son who has a sort of diffuse mild dyslexia coupled with ADHD which made it worse, and a daughter with classical severe dyslexia — it would not surprise me in the least if intrapartum hypoxia is not discovered to be a major component.

Nor do they know that fetal readiness for labor (including protection against hypoxia and readiness for newborn transitions after birth) is coordinated with preparation of the mother's body for labor, breastfeeding and mother - infant attachment.

The prone or side sleep position can increase the risk of rebreathing expired gases, resulting in hypercapnia and hypoxia.54, — , 57 The prone position also increases the risk of overheating by decreasing the rate of heat loss and increasing body temperature compared with infants sleeping supine.58, 59 Recent evidence suggests that prone sleeping alters the autonomic control of the infant cardiovascular system during sleep, particularly at 2 to 3 months of age, 60 and can result in decreased cerebral oxygenation.61 The prone position places infants at high risk of SIDS (odds ratio [OR]: 2.3 — 13.1).62, — , 66 However, recent studies have demonstrated that the SIDS risks associated with side and prone position are similar in magnitude (OR: 2.0 and 2.6, respectively) 63 and that the population - attributable risk reported for side sleep position is higher than that for prone position.65, 67 Furthermore, the risk of SIDS is exceptionally high for infants who are placed on their side and found on their stomach (OR: 8.7).63 The side sleep position is inherently unstable, and the probability of an infant rolling to the prone position from the side sleep position is significantly greater than rolling prone from the back.65, 68 Infants who are unaccustomed to the prone position and are placed prone for sleep are also at greater risk than those usually placed prone (adjusted OR: 8.7 — 45.4).63, 69,70 Therefore, it is critically important that every caregiver use the supine sleep position for every sleep period.

In a recent systematic review, the pooled mean prevalence of head covering among SIDS victims was 24.6 % compared with 3.2 % among control infants.154 It is not known whether the risk associated with head covering is attributable to overheating, hypoxia, or rebreathing.

«A lot of that is associated with oxygen minimum zones, hypoxia in the ocean, dead zones.

At this height, oxygen levels are about 40 per cent lower than at sea level, and lowlanders experience hypoxia — associated with headaches, fatigue and smaller fetuses.

The hypoxia - treated rodents lived more than 6 months, compared with about 2 months for untreated animals, Mootha and his colleagues report online today in Science.

But there may be other ways to harness the pathway that controls hypoxia, for example with certain drugs.

Given that inactivity and hypoxia are frequently associated with several important cardiovascular and respiratory diseases there is a suggestion that for skeletal muscle, inactivity is worse compared to hypoxia.

They argue that fetal monitoring trials have focused on uncommon outcomes, such as cerebral palsy, which is rarely linked to hypoxia during labour, and say «we should be focusing on other forms of evidence relating to the more common outcome with serious long term implications — namely, neonatal encephalopathy.»

He argues that «most of the fetuses identified as being at risk of hypoxia are not» and highlights a review of trial data for nearly 37,000 women that found no difference in perinatal mortality between labours with electronic fetal monitoring versus intermittent auscultation.

In the Black Sea, hypoxia ended with the breakup of the Soviet Union and the curtailment of fertilizer subsidies.

From this the scientists deduced that short - term acclimation ability observed in adults after one week does not predict the ability of their offspring to cope with low oxygen, if reared under moderate hypoxia.

Dr Truebano said: «Along with ocean acidification and rising temperatures, hypoxia is considered one of the main threats to species within the marine environment — but it is currently the least talked about.

Scientists with the U.S. Geological Survey, the Illinois - Indiana Sea Grant and partners recently found that dead zones caused by hypoxia, the depletion of oxygen in water, are unexpectedly variable in Lake Erie, sometimes disappearing and reemerging elsewhere in the matter of hours.

The team of clinical neuropsychologists at Saarland University have used this training programme on eleven stroke patients, nine patients with brain trauma injury and four hypoxia patients.

One possible reason for the shift is that tumors must sometimes cope with a lack of oxygen, or hypoxia — hence the need for anaerobic energy production.

The research, led by the University of Southampton and UCL, which took place on Mount Everest, assessed the mechanisms by which low oxygen levels in the body — known as hypoxia — are associated with the development of insulin resistance.

A leading researcher in developmental programming, Challis says this study opens the door to thinking about combating fetal hypoxia in humans with antioxidant therapy.

Finally, alcohol and cigarette smoking were associated with a decreased risk of intrauterine passing of meconium, a sign of acute fetal stress and / or hypoxia; methamphetamine, with an increased risk.

The study shows that the optic nerve could be damaged due to hypoxia without a spike in eye pressure, a finding that could help unravel the details of glaucoma sufferers with normal eye pressure levels.

One patient with a history of asthma experienced shortness of breath and hypoxia; another patient had thrombocytopenia.

Planes are equipped with oxygen - monitoring sensors, but that may not help if the crew are already affected by hypoxia, says Thomas Smith at the University of Oxford, who specialises in aerospace medicine, or if they misinterpret the signals, as is thought to have occurred in the 2005 crash, says Daniel Rooney at the Institute of Aerospace Medicine in Cologne, Germany.

Harris et al. [2] also provided evidence of the presence of retinal hypoxia in the early stages of diabetes by showing that contrast sensitivity was improved when patients with early diabetic retinopathy were made hyperoxic.

The study, «A Multi-Center Clinical Trial to Evaluate the Effectiveness of Intermittent Hypoxia Therapy in Individuals with Spinal Cord Injury (SCI),» is being conducted by an experienced team of scientists and clinicians at three leading SCI rehabilitation institutions: Shirley Ryan AbilityLab (lead investigator, William Zev Rymer, MD, PhD), Kessler Foundation (Gail Forrest, PhD; Steven Kirshblum, MD), and the University of Miami (Monica A. Perez, PT, PhD).

The effects of chronic prenatal hypoxia on the fetal and adult offspring cardiovascular system are prevented by maternal treatment with vitamin C during pregnancy.

The implications of these data are that maternal treatment with antioxidants may provide possible therapy against the programming effects on vascular dysfunction in pregnancy complicated by fetal hypoxia, such as during placental insufficiency, preeclampsia, gestational diabetes or high altitude pregnancy.

Therefore, the primary novelty of the discoveries reported here is that programming by prenatal chronic hypoxia of cardiac and vascular dysfunction in adulthood follows the induction of oxidative stress in the fetal heart and vasculature, and that cardiac and endothelial dysfunction in adulthood can both be prevented by maternal treatment with antioxidants during pregnancy.

Patients with heart disease experience hypoxia regularly.

However, 24 genes were significantly downregulated following hypoxia, with 12 still significantly downregulated after recovery.

Insight into the novel role that NMDA receptors play in retinal responses to hypoxia may be derived from study of the coordinated expression patterns of genes that interact, either directly or indirectly, with the NMDA receptor; namely, the NMDA interactome.

Acute intermittent hypoxia is a new strategy that may have the potential to increase neuroplasticity in individuals with injuries of the spinal cord.

«Now, with the help of gene therapy and stem cells we can help reactivate the body's response to hypoxia and save limbs.»

Pregnant rats subjected to hypoxia were placed inside a chamber, which combined a PVC isolator with a nitrogen generator [13], [28].

Conclusions: The identification of gene expression alterations as a function of hypoxia and recovery from hypoxia is important to understand the molecular mechanisms underlying retinal dysfunction associated with a variety of diseases.

Analyses were performed with 5 animals per group (control, 3 h of hypoxia, and 24 h or recovery after 3 h hypoxia) to decrease bias that may be introduced by donor - specific gene expression patterns.

The buoy has been collecting water quality data since 2011 — data now powering new research that captures with unprecedented clarity the lakewide hypoxia afflicting this Great Lakes estuary every summer and fall.

The interaction of superoxide with nitric oxide destabilizes hypoxia - inducible factor - 1α.

New models of perinatal hypoxia were developed in rats with emphasis on the potential protective effect of pre-conditioning by a previous fetal hypoxic period.

Quantitative analysis of Snail and vimentin protein expression by Western blotting revealed a 3 - to 4-fold increase in nuclear Snail expression and an 8 - to 9-fold increase in vimentin expression in the MDA - MB 231 F3 and BCM2 F3 cells compared with the parental and hypoxia - exposed A3 subpopulations (Figure 6c).