Sentences with phrase «with immunologic»

«Together, we devised more and more specific ways to tamper with each immunologic pathway.

Human milk is a unique, species - specific, complex nutritive fluid with immunologic and growth - promoting properties.

Not exact matches

The study, supported in part by the National Institutes of Health (NIH), marks the first time that tolerance to the allergen (i.e., peanuts) was measured in conjunction with key immunologic changes.

Experts recommend breastfeeding exclusively for the first 6 months, and sustained for up to two years or longer with appropriate complementary feeding for the nutrition, immunologic protection, growth, and development of infants and toddlers.

Pasteurized donor human milk can be used to help infants with a variety of conditions, including prematurity, allergies, feeding intolerance, immunologic deficiencies, post-operative nutrition, treatment of some infectious diseases, and treatment of certain inborn errors of metabolism.

Studies comparing human milk from preterm mothers with that from term mothers suggest that these immunologic benefits may be even greater for preterm infants because secretory immunoglobulin A (IgA), lysozyme, lactoferrin, and interferon are found in greater concentrations in preterm human milk compared with term milk.2 — 4 Very low birth weight (VLBW) infants do not benefit from the transplacental transfer of maternal immunoglobulins that occurs primarily after 34 weeks of gestation.5 These infants are exposed to abundant pathogenic organisms during neonatal intensive care unit (NICU) hospitalization and may benefit from the host defense factors present in preterm human milk.6 — 9

Adults with GI disorders and organ donation recipients can also benefit from the immunologic powers of breast milk.

There are only a few instances of the polymer being assayed in the milk of women with implants; the concentrations are not elevated over control samples.20 There is no evidence at the present time that this polymer is directly toxic to human tissues; however, concern also exists that toxicity may be mediated through an immunologic mechanism.

Data also show that there was a wide variation in the magnitude of cholesterol reduction that patients achieved with bococizumab, even among patients who did not develop the immunologic response.

As I neared the end of the research phase of my training, I became increasingly interested in the immunologic aspects of tropical diseases, particularly in the possibility that infection with the American trypanosome induces autoimmune myocarditis.

The immunologic changes seen in problem drinkers were associated with elevated levels of stress and cue - induced alcohol craving and anxiety.

Researchers led by a team at Duke University identified these immunologic variations by studying blood samples collected from people living with HIV by the NIAID - supported Center for HIV / AIDS Vaccine Immunology (CHAVI).

Some of the abnormalities James saw in this study have already been associated with gastrointestinal and immunologic dysfunction.

«Now an option with better immunologic protection is available, as our study shows.»

Although researchers have suspected that maternal cells might play a role in provoking immunologic problems, this study found that in individuals with type 1 diabetes, at least, those cells might actually be lending a helping hand.

By developing blood biomarkers and «immunologic signatures» related to antigen - specific T - cell responses, the researchers hope to identify individuals with latent TB infection who are at greatest risk for progression to active disease, allowing development of prevention strategies to target those at highest risk in areas with high rates of infection (usually low - and middle - income countries), as well as high income countries such as the U.S., where factors such as recent infection and HIV co-infection are associated with an increased risk of progression to active TB.

Immunologic correlates of protection against challenge after intramuscular immunization of mice with rotavirus.

These observations, along with the characteristic morphology and immunologic findings in the present case, indicated that the disease was consistent with the features of leukemic BPDCN.

And again, that is an immunologic drug, and it was approved on the basis of prolonged relapse - free survival — that is, prolonged time to return of the tumor compared with ipilimumab, which as I mentioned was the standard since 2015.

Immunologic checkpoint blockade with anti — cytotoxic T - lymphocyte — associated antigen 4 (CTLA - 4) or anti — programmed death 1 (PD - 1) / programmed death ligand 1 (PD - L1) agents seems to have some degree of clinical efficacy in advanced mucosal melanoma, although data are limited to smaller retrospective series or subset analyses of prospective trials.

The potential for synergy with the combination of immunologic checkpoint blockade and radiotherapy has gained significant attention.

The intent of the effort is to build off the identified immunologic factors that may be modulated to improve immunotherapy for CRC patients, with the goal that the biomarkers and treatment strategies identified in the manuscript will become part of the routine management of colorectal cancer (CRC).

In a study involving 12 patients with bladder cancer, who also underwent prostate surgery as part of their treatment, she identified the ICOS molecule as the first immunologic marker identified in both tumor tissues and the systemic circulation that can be used as a biomarker for monitoring of anti-CTLA-4 treated patients as a possible marker of therapeutic activity.

Since DENV and ZIKV are closely related and cross-reactive in many immunologic assays, it is currently uknown whether a first infection with one virus might protect or worsen a subsequent infection with the other virus.

NIAID collaborates with industry and academia to advance research on infectious and immunologic diseases; to develop and test new methods of prevention, diagnosis, and treatment; and to accelerate the translation of research findings into medical products.

Her laboratory focuses on (1) the use of next generation sequencing to define the microbiome and host immunologic features in patients with human diseases and (2) developing custom computational tools for the identification of novel human commensals and pathogens in these inpatient populations, and (3) using statistical and functional biological methods to understand the complex interplay between the human microbiome and host biology.

This study established the MTD of the cyclophosphamide - huKS - IL2 combination (mainly limited by IL - 2 side effects), the pharmacokinetics of huKS - IL2 and its systemic immunologic and immunogenic effects in patients with solid tumors (BMC Cancer.

Maiman said these problems arise from not exposing the infant to the helpful bacteria in the vagina that gives the baby «an immunologic advantage as compared with babies born via cesarean delivery.»

The increased anti-gliadin antibody response and its association with GI symptoms points to a potential mechanism involving immunologic and / or intestinal permeability abnormalities in affected children.»

Food sensitivities are mediated by multiple pathogenic mechanisms, and there are numerous clinical and immunologic complexities associated with food sensitivities.

Studies show that even in high concentrations, buckwheat flour and its purified proteins have no immunologic reactions for patients with celiac disease.

Despite all of the clinical and immunologic complexities associated with food sensitivities, the single common component of all diet - induced inflammatory reactions is proinflammatory and proalgesic mediator release from white cells.

Dr. Horwitz provides integrative medical consultations to people with a variety of medical concerns, including allergic diseases and asthma, immunologic and rheumatologic disorders, heart disease, hepatitis and cancer.

In addition, improvement in immunologic responses has been demonstrated with zinc treatment in obese children and adolescents (Chandra and Kutty 1980).

The company has several «investigational compounds in various stages of development» for the treatment of cancer and immunologic diseases, three of which it is developing with Biogen Idec and one with BMS.

TPE is an apheresis (removal of impurities from blood) treatment in which plasma contaminated with damaging auto - antibodies, toxins or abnormal proteins is separated from the patient's flowing blood and exchanged with donor plasma that is returned to the patient to render the patient less susceptible to or free from immunologic attack or other pathologic processes.

Dr Jean Dodds: «Many veterinarians trace the present problems with allergic and immunologic diseases to the introduction of MLV vaccines...» 9

This round of immunologic responses can occur with each infected bite, as well as with death of each adult worm.2, 4

Over time, the cats treated with stem cells showed statistically improved respiratory signs based on a variety of measurable factors, including blood counts, immunologic tests, and CAT scans.

Other tests that may be used include: ultrasound, specialized radiologic studies (e.g. nuclear scan, CT or MRI scan, dye contrast studies), bone marrow aspirate, lymph node aspirate, endoscopy (direct examination of the stomach, colon, or lung with a specialized scope & camera), and immunologic studies.

Other heritable conditions that are related to loss of genetic diversity and inbreeding include cataract, various heart valve defects including pulmonic stenosis, hydrocephalus, cysteine urolithiasis, and hiatal hernias; immunologic disorders that include a propensity for severe demodectic mange indicative of immunodeficiency, allergies associated with atopic dermatitis and ear infections, and autoimmune diseases such as hypothyroidism; and cancers including glioblastoma, mast cell sarcoma and lymphoma [15, 16].

The medicine faculty have numerous ongoing research projects including: genetic investigations of airway obstruction and immunologic disorders of horses along with the investigation of several infectious diseases including: equine herpesvirus, strangles, Lyme disease, leptospirosis, viral hepatitis and salmonellosis.

I also manage a clinical immunology laboratory, which performs research - based immunological testing in samples from horses with suspect underlying immunologic disorders, submitted by referring veterinarians from academic and private hospitals in the country.

Evaluation of cognitive learning, memory, psychomotor, immunologic, and retinal functions in healthy puppies fed foods fortified with docosahexaenoic acid - rich fish oil from eight to 52 weeks of age.

Efficiently worked with Senior Staff in the Clinical Pharmacology bioanalytical laboratory to provide bioanalytical assay capabilities for the evaluation of new immunologic - targeted biologic therapeutics.

Immunologic and psychologic therapy for patients with chronic fatigue syndrome: a double - blind, placebo - controlled trial