The results for breast cancer are in line
with previous research, but the true effect of alcohol on risk of
ischaemic heart disease remains uncertain, say the editorial authors.
Among the 50 trials, 30 were primary prevention trials (general populations, smokers and workers exposed to asbestos, patients
with oesophageal dysplasia, male physicians, patients
with non-melanoma skin cancer, postmenopausal women, patients undergoing chronic haemodialysis, patients
with end stage renal
disease, ambulatory elderly women
with vitamin D insufficiency, patients
with chronic renal failure, older people
with femoral neck fractures, patients
with diabetes mellitus, elderly women
with a low serum 25 - hydroxyvitamin D concentration, health professionals, people
with a high fasting plasma total homocysteine concentration, or kidney transplant recipients), and 20 were secondary prevention trials (patients
with cardiovascular
disease, coronary
heart disease, acute myocardial infarction, unstable angina, transient
ischaemic attack, stroke, angiographically proved coronary atherosclerosis, vascular
disease, or aortic valve stenosis).
Associations of egg and cholesterol intakes
with carotid intima - media thickness and risk of incident coronary artery
disease according to apolipoprotein E phenotype in men: the Kuopio Ischaemic Heart Disease Risk Factor
disease according to apolipoprotein E phenotype in men: the Kuopio
Ischaemic Heart Disease Risk Factor
Disease Risk Factor Study.
Risks for future ill - health were common,
with high rates of smoking, and emerging type 2 diabetes and
ischaemic heart disease (conditions more typical of adulthood).