Sentences with phrase «with ischemia»

Inflammation with ischemia can result in irreversible interstitial fibrosis.

To investigate this hypothesis, the authors injected a collagen hydrogel into the kidneys of mice with ischemia / reperfusion damage and assessed the consequences at four weeks.

Not exact matches

As a result, the animals treated with blueberry, spinach, or spirulina were reported to have reduced ischemia / reperfusion - induced apoptosis and cerebral infraction.

In preclinical studies, hypothermia and anti-oxidant treatment with N - acetylcysteine (NAC) are neuroprotective following neonatal hypoxic ischemia in females, but less so in males.

Jenkins and her team plan to build upon these results with preclinical and clinical studies aimed at understanding the injury mechanisms underlying hypoxic ischemia and how they differ in males and females.

Hypothermia alone, the current standard of care, neuroprotects roughly 50 percent of newborns with moderate to severe hypoxic ischemia.

Powers is planning expand his study size and is partnering with another CCTS - funded stroke investigator who developed an animal model of ischemia in order to analyze micro-RNA released in brain tissues at the precise area around a blocked blood vessel.

Chen — together with clinical partners C. Keith Ozaki, MD, FACS, a surgeon at Brigham and Women's Hospital who has expertise in leg ischemia, and Joseph Woo, MD, the head of cardiothoracic surgery at Stanford University — have developed a patch that fosters the growth of new vessels while avoiding some of the problems of other approaches.

Cerebral ischemia is a disorder caused by insufficient blood flow to the brain and its early detection with MRI contrast agents is vital for survival of patients.

In vivo results demonstrated the patches with pre-organized structure reflected a marked improvement in reducing the prevalence of ischemia, while the patches with no organization resulted in the «hairball» situation as described by Chen.

In the Mental Stress Ischemia Mechanisms Prognosis study, 678 adults (average age 63) with heart disease delivered a speech while researchers measured their blood pressure and heart rate, took imaging pictures of their hearts and measured the constriction of tiny arteries supplying blood in their fingers.

A total of 3,155 patients presenting with symptoms suggestive of cardiac ischemia were included in the analysis.

«Based on the results seen with ADRCs in the PRECISE trial, we designed ATHENA to look at these cells as a possible treatment option for people with refractory chronic myocardial ischemia.»

Dr. Henry presented «Final Results for THE ATHENA TRIALS: Autologous Adipose Derived Regenerative Cells (ADRCs) for Refractory Chronic Myocardial Ischemia with Left Ventricular (LV) Dysfunction» on Thursday, May 5, 2016 at 11:00 a.m. ET.

«Humans risked limb ischemia in exchange for bipedal walking: A detailed comparison of mouse and human blood vessels with three - dimensional imaging.»

The higher sensitivity of the cerebellum to what we interpret to reflect changes in vascular reactivity with marijuana abuse is consistent with clinical findings that report strokes associated with marijuana abuse are more frequently localized in the posterior circulation and ischemia is most frequently observed in cerebellum (25, 54 ⇓ — 56).

In the ExMI group, more severe ischemia was linked with a greater decrease in progenitor cells.

In addition to her expert skill as a clinician, Dr. Frontera also has many research interests including identifying biomarkers and predictors of early brain injury and vasospasm / delayed cerebral ischemia after subarachnoid hemorrhage and their impact on outcome; determining the efficacy of therapeutic strategies and developing guidelines for the management of patients with intracranial hemorrhage; evaluating the cost, length of stay, quality of life, functional and cognitive outcomes in a broader population of intracranial hemorrhage patients; developing guidelines for the integration of palliative care into the intensive care unit setting; and evaluating the relationship of Zika virus infection, Guillain - Barre, and other neurologic disorders.

Electroacupuncture improves cognitive function through Rho GTPases and enhances dendritic spine plasticity in rats with cerebral ischemia - reperfusion.

â $ œWe have found neuroprotective compounds that can limit damage to the brain during ischemia associated with stroke and other brain injuries, but have minimal side effects, â $ says senior author Stephen Traynelis, PhD, professor of pharmacology at Emory University School of Medicine.

In some patients with coronary artery disease, mental stress may precipitate ischemia — a deficiency in blood flow to the heart â $ «a risk factor for adverse events and death independent of other cardiovascular risk factors such as smoking, cholesterol and diabetes.

Consistent with this finding, EPOR protein levels continued to rise for 72 h after the end of ischemia in rat retina [64].

Electrocardiography showed prolongation of the PR interval with normal QRS complexes and no indication of ischemia.

In line with previous studies12, 13,15,17,20 our analyses show that the investigation of the impact of post-mortem ischemia in tissue transcriptomes is essential to properly interpret gene expression estimates obtained from post-mortem tissue samples.

The authors highlight that these sex differences have to be considered before starting metabolically active drugs, because higher plasma glucose levels were also associated with increased glucose kinetics, in diabetic patients, and this might have clinical relevance especially during ischemia.

Dr. Losordo is internationally recognized for his groundbreaking work in the use of gene, protein, and cell therapies to promote new blood vessel growth in patients with peripheral artery disease (PAD) and critical limb ischemia (CLI).

«In this GRF - supported study, we treated retinas with three related but different, high IOP - induced ischemic conditions: preconditioning (short ischemia, causing litter injury), injurious (prolonged ischemia, severe injury), and tolerant (preconditioning followed by prolonged ischemia, protected from injury).

We then evaluated whether the encapsulation of hPSC - CDH5 + cells in PA - RGDS could enhance long - term cell survival and vascular regenerative effects in a hind - limb ischemia model with laser Doppler perfusion imaging, bioluminescence imaging, real - time reverse transcription - polymerase chain reaction, and histological analysis.

The authors report an atypical presentation of TA in a woman who presented with signs and symptoms of limb claudication and mesenteric ischemia.

The data on the prevalence of myocardial ischemia on myocardial perfusion single photon emission computed tomography (MPS) in symptomatic patients with zero CACS and low to intermediate risk probability is lacking and controversial.

Ambient levels of PM 2 days before submaximal exercise testing were significantly associated with increased ST - segment depression during the test.17 This finding suggests that air pollution exposure conveys a greater susceptibility to myocardial ischemia, as demonstrated in an experimental study of dogs exposed to CAP.175 These results also offer insight regarding the relationship between exposure to PM and the timing of AMI.11 Significant associations were identified between symptom onset and both acute (levels within 2 hours before symptoms) and subacute (previous - day average concentration) exposures to PM2.5.

Patients with critical limb ischemia have leg pain even when resting and sores that don't heal because of lack of circulation, Lookstein said.

For the study, Lookstein's team followed 53 patients with critical limb ischemia who had a total of 94 drug - eluting stents implanted to treat leg arteries that would not stay open after angioplasty alone.

Low - dose supplemental testosterone treatment in men with chronic stable angina increased exercise time preceding induced myocardial ischemia as defined by ST depression on EKG.80 Testosterone replacement therapy has also been proven to reduce insulin resistance, visceral adiposity, and cardiovascular risk.

As a result, the animals treated with blueberry, spinach, or spirulina were reported to have reduced ischemia / reperfusion - induced apoptosis and cerebral infraction.

With healthy blood circulation, the risk of a sudden blood clot (ischemia) is significantly reduced.

Endurance athletes frequently report gastrointestinal impairment during competition, which can include dangerous and debilitating conditions such as nausea, bloating, pain, vomiting, abdominal angina, bloody diarrhea, endotoxemia, hemorrhagic gastritis, and ischemic colitis.28, 29 Causes of gut distress are considered multifactorial, with gastrointestinal ischemia being important, along with mechanical position (e.g. runners versus cyclists) and nutrition.

(Closely associated with stroke, ischemia is a condition marked by insufficient blood flow to the brain.)

Those with sickle - cell anemia or congenital heart defects are at greater risk for a condition called brain ischemia or cerebral ischemia.

The greatest reason to supplement with L - carnitine is completely unrelated to weight loss; it appears to be invaluable for heart health, helping to prevent, even reverse ischemia, stabilize irregular heartbeats, reduce incidents of angina, lower triglycerides and maintain a beneficial cholesterol profile.

Diffuse pallor of dermal connective tissue with pale - staining, smudged, collagen probably results from tissue ischemia.