Sentences with phrase «with key phases»

They assessed gene activity at time points known to correspond with key phases of disease: the «induction phase,» the time before the peak level of photoreceptor cell death; the «execution phase,» when the highest rates of photoreceptor cell death occur; and the «chronic phase,» during which photoreceptor cell death continues at somewhat reduced levels.

Not exact matches

What I have learned from many years of working with tech - enabled growth companies; on both sides of mergers and acquisitions; and angel, private equity and venture capital investments, is that accretion of IP value is the key element to supporting overall enterprise value — representing scalability in phases of rapid growth and supporting attractive multiples during the fundraising and exit phases.

Airbus is drawing up contingency plans to phase out production of the world's largest jetliner, the A380 superjumbo, if it fails to win a key order from Dubai's Emirates, three people familiar with the matter said.

Key benefits include the logistical ease of working with local companies, during both the construction phase and the ongoing servicing of a project.

Companies can also keep setting up new PUP plans for key executives, with revised goals that make sense for the company in its latest growth phase.

On June 6 Finance Minister Jim Flaherty reintroduced his spring federal budget, which was never passed in the rush to an election, with a key twist: Flaherty added a measure to phase out the $ 2 - per - vote subsidy to political parties by 2015 - 16.

For entrepreneurs who successfully complete the education phase, the Entrepreneurs in Residence (EIRs) at MaRS and partner organizations in the Ontario Network of Excellence (ONE) will provide mentoring, along with the key support services that are typically required for the successful launch and operation of a new business.

In August, Mr. Flaherty met with his advisory panel as well as selected business representatives and academics to discuss key issues facing Canada and «to shape the policies and initiatives of the next phase of Canada's Economic Action Plan».

For example, what level of capital will be needed to get to a working prototype or to the beta phase with a key customer?

Entrepreneurs who are on their way with their businesses, and are looking to succeed in the next phase of development of their endeavor often ask me: «What is the key to turn a small startup into a large - scale business?

Those unfamiliar with Whitehead's systematic terminology in Process and Reality may wish to read Donald Sherburne's explanation in A Key to Whitehead's Process and Reality.2 He explains how Whitehead's categories apply to the various phases of concrescence of an actual entity.

Led by Su Birch, former CEO of Wines of South Africa (WOSA), the campaign is targeting EU trade in the first phase of its activities, but will be expanding its communication to include wine lovers in key markets across the region with a follow - up social media strategy.

Highly innovative, fully integrated packaging supplier with impressive in - house set up is recruiting for a Flexo Printer to join their outstanding operation and play a key role in the next important phase of growth.

CGF is urging all consumer goods companies to phase out harmful hydrofluorocarbons (HFCs) focusing on four key points; the installation of new refrigeration equipment in markets where viable, engagement with stakeholders to overcome barriers in markets where installation is not currently viable, reduction of the environmental impact of existing refrigeration systems and the development of individual targets and action plans to measure the first three points.

«As we reflect on a decade of business, having increased sales (+60 %), and reinforced our relationships with key distributor partners we have readied the company for a bright future as we prepare for the next phase of growth.»

A World Rugby delegation, led by Chief Executive Brett Gosper and Tournament Director Alan Gilpin, met with FFR President Bernard Laporte and leading officials of the FFR to further key areas of delivery within the initial establishment phase, including:

The keys to managing this phase effectively are to alternate rest with activity.

Practically, the lack of time and resources during the transition will make the EU the overwhelming priority; politically, other countries will want to wait and see what kind of deal we strike with the EU before negotiating their deal with us, and thereby also increase their leverage; and legally, we will almost certainly be remaining in the customs union as a result of the phase one deal, with the key prize of agriculture tariffs and standards already guaranteed to be out of our hands.

«In the second phase of the project, we will be deploying 10,000 HD cameras, world class e-Government solution and data centre solution, one key alarm, metro fibre network to serve as backbone for communication and unified communications with smart phones for first respondent agencies such as police, fire service, Lagos State Traffic Management Authority (LASTMA), Lagos State Ambulance Service (LASAMBUS), Vehicle Inspection Office (VIO), among others.»

He, along with Rep. Daniel Donovan, Mayor Bill de Blasio and Borough President James Oddo announced Tuesday that by skipping that step, the project has moved into the key design phase.

Several key areas were still not completely resolved, with legislators and lobbyists following the process indicating that there were last - minute tinkers with the way the minimum wage would be phased in.

«The key to this metamaterial and metadevice is vanadium dioxide, a phase change crystal with a phase transition that is triggered by temperatures created by an electric current,» said Lei Kang, research associate in electrical engineering, Penn State.

Instead of a detailed waveform required with tonometry, their method needs just the shape of a patient's pulse wave for the mathematical model, called intrinsic frequency, to calculate key variables related to the phases of the patient's heartbeat.

A key aspect of the fly's sound localization system is that its eardrums beat out of phase with each other.

Environmental management can potentially devise separate strategies to target key phases in the lifecycle of males and females, respectively, with the aim of minimising the influence of climate change on their development and ultimately the success of the species.»

A key test will come with a Phase IIb study by Benevolent to assess a previously unsuccessful compound from Johnson & Johnson in a new disease area - this time for treating Parkinson's disease patients with excessive daytime sleepiness.

With the completion of the first phase of the Human Genome Project in 2000, and the advent of sequencing technologies that can detect gene variations such as single nucleotide polymorphisms (SNPs), for the first time scientists have the tools in hand to find the key immune genes and genetic networks that play roles in vaccine response.

«We are really excited to now be moving forward with the next phase of our trial, which will be a key step in the evaluation of olaparib in advanced prostate cancer.»

The surface, and in particular the interaction of molecular radicals with the surface, plays a key role for both, entropy and selective dissipation, highlighting fundamental differences of surface - supported reactions compared to gas - phase or solution chemistry.

Our group has 3 major goals: Develop novel therapeutic approaches based on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple myeloma

Because the polyT repeat is reported as the key variant to define TOMM40 clades A and B, 12 we used this marker and APOE isoform information to perform analyses based on phylogenetic groups as described by Roses et al. 12 Haplotype phase was estimated using PHASE software.22 The phylogeny, which represents the evolutionary relatedness of the haploytpes, was estimated using neighbor - joining with 10 000 bootstrapping replicates in the CLC DNA workbench (CLC bio, Aarhus, Denmark)(Supplemental Figure 3; http://neuroscienceresearch.wustl.edu/Pages/cruchaga2011.aphase was estimated using PHASE software.22 The phylogeny, which represents the evolutionary relatedness of the haploytpes, was estimated using neighbor - joining with 10 000 bootstrapping replicates in the CLC DNA workbench (CLC bio, Aarhus, Denmark)(Supplemental Figure 3; http://neuroscienceresearch.wustl.edu/Pages/cruchaga2011.aPHASE software.22 The phylogeny, which represents the evolutionary relatedness of the haploytpes, was estimated using neighbor - joining with 10 000 bootstrapping replicates in the CLC DNA workbench (CLC bio, Aarhus, Denmark)(Supplemental Figure 3; http://neuroscienceresearch.wustl.edu/Pages/cruchaga2011.aspx).

I know that nutrition is key with losing body fat and I eat relatively well, most of the time anyway my problem is, I have put on a lot of unwanted bodyfat by not eating «clean» during my bulking up phase, I'm now a lot bigger than I would like and am going to start doing fasting training two / three times a week, and on the days I am training weights I already do 10/15 HIT training followed by a fast paced uphill walk, would this help me achieve my goals?

However understanding the technical key points of each phase of the Power Snatch technique will help you identify the weakest link in the chain and address this weakest link with appropriate corrective exercises.

To help you be successful we have 27 videos with key information regarding the various phases and recipe demonstrations.

With Scott Derrickson tapped to direct «Dr. Strange,» one of the key films in place for Marvel Studios» Phase III

A key way of doing this in the third and fourth grades is during the brainstorming phase [before students write] is to let the kids who want to and who think visually and graphically draw with colored pencils.

There are several key aspects here that are often overlooked - the point of an MVP is that you need to put it in front of users as soon as possible in order to get real «actionable» feedback that you can then feed back into your next phase of development (learn)-- thus asking the right questions — to gain «actionable metrics» — actual figures that will help you with your development is vital (rather than «vanity metrics» — numbers that sound good, but can't be used to improve the product).

It guides central office staff through a series of questions to generate information to use in discussions with key district leaders and helps districts identify the first phases of the transformation process based on such considerations as ease or urgency.

In one case study, children were grouped by phonics phases across the school, meaning some key stage 2 children were placed with others in key stage 1.

With dozens of specific tools organized around key phases of instruction, Tools for Thoughtful Assessment meets this challenge directly, and provides administrators with tools to help all teachers meet their needs, their students» needs, and their professional development goWith dozens of specific tools organized around key phases of instruction, Tools for Thoughtful Assessment meets this challenge directly, and provides administrators with tools to help all teachers meet their needs, their students» needs, and their professional development gowith tools to help all teachers meet their needs, their students» needs, and their professional development goals.

A self assessment that is aligned to each phase and domain of design that tracks a designer's current knowledge / understanding / experience with a given outcome as well as his / her completion of a key product or process associated with this outcome.

However, where these settings undergo significant change, for example through merging with another school or by adding a new phase or a key stage, they will normally have a section 5 inspection as their next inspection instead of a short inspection.

The aim of this resource is to provide you with an overview of: — the key phases and activities involved in a performance and development cycle — your role in the performance and development cycle — the resources that will support you in each of the phases.

The Tennessee Department of Education worked with BloomBoard to design a phased approach to implementing micro-credentials that allowed for effective asynchronous collaboration and aligned to the key competencies they identified.

Plastic Logic, which was founded by two Cambridge University professors 10 years ago, is planning a two - phased entry into the market that will begin in the second half of 2009 with pilots and trials with «key partners».

Diging out with my mortgage loan and wondering when ou when will I have any dividend income have to cut my expenses, but its hard to do, but key to success is to have goals right then you can move to phase two, implementing them http://www.mypersonalfinance.org/?p=30

«It is key to work with someone who is knowledgeable about distribution in this phase of life,» said Till.

The key formula to reaching this level is to pass through phases one and two and stick with your site with the same level of commitment over a significant period of time.

-- A new full 100 - hour Japanese Tactical RPG for Android — Enhanced battle system including special chain skills, break and overkill — High level of freedom: explore the world to progress through the story in any order you wish — Use various actions to modify the battle field during exploration phases — Create over 200 different items and skills — Capture monsters and have them fight in your party — High resolution graphic assets — Support for touch & keyboard with key mapping — Xperia Play optimized

Open Beta is the phase in which everybody can take part at no cost, with no key required.