Sentences with phrase «with large numbers of samples»

Unfortunately, with large numbers of samples and increasingly dense genomic data, this two - step approach carries a significant computational burden.

We've had to deal with a large number of samples over a short period, working long hours and sometimes weekends to get results.»

Not exact matches

One of the first such studies25 linked slapping and spanking in childhood with psychiatric disorders in adulthood in a large Canadian sample, and its findings have since been supported by an ever - growing number of studies.

The MGH team has assembled a large number of DNA samples from HD patients who contributed them for research to the Massachusetts HD Center Without Walls and through collaboration with the Huntington Study Group.

Tissue engineers have been unable to grow epidermis with the functional barrier needed for drug testing, and have been further limited in producing an in vitro (lab) model for large - scale drug screening by the number of cells that can be grown from a single skin biopsy sample.

The assay was implemented in five countries and tested using a large number of clinical samples from travelers and patients living in areas with a high level of exposure to Zika virus and other flaviviruses.

Researchers from the University of Leicester's Department of Cancer Studies and Molecular Medicine, in collaboration with Cleaver Scientific Ltd., have developed a novel, high throughput method of performing the assay which is set to overcome this problem and to push down the costs of processing large numbers of samples.

By looking at the changes in healthy food availability in a sample of food stores in the city of Baltimore between 2006 and 2012, researchers found that corner stores, particularly in neighborhoods with large numbers of black residents, were modestly but significantly more likely to carry a larger number of those healthful choices.

Twenty - four hours after the injection, the researchers saw large numbers of immune system white blood cells in tissue samples of the rodent brains near the site of injury of those mice injected with the cytokine IL - 1b, but not in the brain tissue of the control group of mice.

With its large sample size, this study had the power to find copy number variants with large effects that occur in more than 0.1 percent of schizophrenia caWith its large sample size, this study had the power to find copy number variants with large effects that occur in more than 0.1 percent of schizophrenia cawith large effects that occur in more than 0.1 percent of schizophrenia cases.

The authors caution that their study was conducted in a country with strong social welfare supports and that while the sample overall was large, the number of children with many symptoms of ADHD was relatively small.

Although none of the German Neolithic samples carries the copy number expansion of the AMY2B gene associated with starch digestion, we find that this gene is present in three copies in NGD, though this is due to a large segmental duplication that is shared with multiple modern dogs, an event separate from the tandem AMY2B duplications.

To test the two hypotheses, we needed to compare Ötzi's mitochondrial DNA with a larger number of modern samples.»

As outlined below, we used a microfluidic quantitative PCR (qPCR) system to elucidate the gene expression profiles of individual human oocytes and small numbers of cumulus cells using a combination of a large number of samples and targets [12], and then extended our studies via the use of parthenogenesis, in conjunction with gene expression profiling, as a functional assay of cytoplasmic maturation of oocytes.

Most published studies entailed small number of subjects; well - designed studies with larger sample sizes are needed to ascertain how this test can reduce clinical diagnostic uncertainty or impact treatment planning.

Although the study had a large sample size, the number of exposed ASD cases was not large enough to provide a stable statistical estimate of the trimester - specific HR associated with influenza infection.

The study provides a large number of cases (children with ASD) and controls (typically developing, or TD, children), along with blood samples from mothers when their children were 2 to 4 years old.

Running as facility of this size requires a massive amount of support and we work closely with the library preparation team that supplies large numbers of DNA templates in a from ready to be sequenced, the Institute's IT team that maintains the extensive amount of compute and storage infrastructure necessary, sequencing informatics which develops software tools to process, analyse, store and track all the data, projects and samples for the Illumina pipeline and the development team which invents novel and improved protocols to take better advantage of this new technology.

For the first time, customers can analyze large sample numbers at reasonable cost in short time with ultra-broad coverage of lipids absolutely quantified to develop new products in medical, nutritional and cosmetics markets.

In general, survey results based on larger numbers of observations are more precise, that is, less prone to sampling variance than those made across groups with fewer numbers of observations.

Even with a sample this large, the number of students attending other religious and secular private schools is still quite small (80 and 102 cases, respectively).

In general, survey responses based on larger numbers of observations are more precise, that is, less prone to sampling variance, than those made across groups with fewer numbers of observations.

For a large number of students, this may include reviewing sample term papers with the format to get a better idea of what to produce.

Tracking a large bond index is difficult and expensive, so index funds pegged to the DEX Universe always use «representative sampling,» selecting a smaller of number bonds with similar overall characteristics.

Naturally, sample size is crucial because skill only surfaces with a large number of observations.

(2) From the group of borrowers identified under paragraph (d)(1) of this section, the data manager identifies a sample that is large enough to derive an estimate, acceptable at a 95 percent confidence level with a plus or minus 5 percent confidence interval, for use in determining the number of borrowers who should be excluded from the calculation of the program cohort default rate due to improper loan servicing or collection.

You keep repeating that a sample size of 100 is small etc etc, but there is a very famous theorem in statistics called «Law of large numbers» that actually will disagree with you.

It was perhaps a bit small, with a sample size of 122 fledglings, but that number is large enough to be at least indicative, although not conclusive.

So far this mutation has been detected in this breed only, with an estimated carrier frequency of 25 % based on a large number of samples collected form dogs originated from Finland, Sweden, United Kingdom and United States.

the collection of a large number of skin samples from marked individual for DNA extraction and analysis, that should permit a better understanding of the genetic structure of the local population of Sea Lion Island, and a first asessment of the relationships of the Falklands population with other populations of the South Georgia stock

-- Strong Law of Large Numbers: The sample mean of any infinite sequence of independent and identically distributed (iid) random variables with mean x converges almost surely to x.

Furthermore, RMSE often increases with increasing geographic area and / or time period being analyzed because larger sampling domains are more likely to contain greater numbers of outliers [Willmott and Matsuura, 2006].

The PDF has been computed in the same way (apart from the reciprocal relationship) as the climate sensitivity PDF in Figure 2 in the original paper, using the same data and error distribution assumptions but with a larger number of random samples to improve accuracy.

In FD - based composite analysis, workers are inevitably met with a choice of developing either a small sample with a select group of large events or a large sample with less event discrimination, since the number of large FD events (> 8 % CR flux reductions) is quite limited.

Frequentists are comfortable dealing with PDFs that are computable from a large number of samples and estimates of error.

As to how fractions of a degree are measured, I would strongly suggest looking at the Central Limit Theorem and the reduction of errors and deviations with large sample numbers.

In an unbiased projection, with a sufficiently large number of samples, overestimates would constitute approximately 50 % of the estimates.

Its large number of observations (32,800 in 2008 and 55,400 in 2010) provide sufficient samples of the non-immigrant sub-population, with 339 non-citizen respondents in 2008 and 489 in 2010.

With such a large sample of data drawn from a number of evaluations that a human expert would take years to complete, big data enables Renoir to uncover new insights.

Among the limits of the present study, it is possible to point out the necessity: 1) to replicate this investigation with a large number of Italian healthy adolescents for the representativeness of the sample; 2) to adopt the double analysis both for positive and negative affect, considering that literature review seems to indicate these two aspects as separate but equally important variables; and, finally, 3) to carry out a longitudinal study, from early adolescence to young adulthood, in order to emphasize the change in these aspects of youth development.

Nevertheless, given the large number of coefficients examined, the significant association of SAD with reduced odds of a suicide attempt among planners should be considered no more than provisional until replicated in independent samples.

Studies with smaller sample sizes showed a larger effect size than studies with larger numbers of subjects.

With regard to the sample size required for valid application of this modeling approach, we are hesitant to speak of sufficient sample sizes, since a large number of observations with little score variation over time (as in our second empirical application) does not necessarily provide richer information than a smaller sample with more fluctuatiWith regard to the sample size required for valid application of this modeling approach, we are hesitant to speak of sufficient sample sizes, since a large number of observations with little score variation over time (as in our second empirical application) does not necessarily provide richer information than a smaller sample with more fluctuatiwith little score variation over time (as in our second empirical application) does not necessarily provide richer information than a smaller sample with more fluctuatiwith more fluctuations.