Sentences with phrase «with large price increases»

Not exact matches

U.S. consumer prices increased in January, with a gauge of underlying inflation posting its largest gain in 12 months, bolstering views that price pressures will accelerate this year.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

With house prices representing a larger share of assets for the bottom three fifths of Americans, this helped increase the differences in wealth between the top and the bottom.

The increases in credit and house prices were inter-related, with credit availability fuelling the price rises, while rising house prices meant people had to borrow larger amounts to achieve home ownership.

Administration officials said they were tailoring the list to minimize price increases for consumers, who buy large quantities of goods from China, and were focusing in part on strategic industries China is attempting to build up with state support.

On the other hand, the earlier increases in dwelling prices were very large, and even with the latest data showing declines, a big cumulative rise in wealth has occurred over the past decade, most of which has not been tapped.

Zero fee trading coupled with certain Chinese - US economic dynamics resulted in a large increase in price via the Chinese Bitcoin markets.

If the heat wave does in fact break and injections begin to increase more in line with the historical weekly builds the large overhang of natural gas in inventory that has been limiting any significant rally in natural gas prices this summer could possibly then turn into a deeper bout of selling.

The retail sales data for June suggest that consumers were, by then, generally well informed of the price changes, with large increases recorded in sales of goods that were expected to rise in price, such as clothing and footwear.

According to the government, signing an agreement with our eighth - largest trading partner will increase exports of Canadian agricultural goods and lower prices for Canadian consumers.

With stocks at currently high multiples on normalized earnings, that type of scenario would probably increase the odds off a deep recession and induce a much larger decline in stock prices.

Other data on Wednesday pointed to steadily rising inflation pressures, with producer prices notching their largest increase in five months in November.

Bonus: The lower the price of an financial asset the easier it is to increase with large percentages.

After a surprisingly large dip in the previous month, eurozone inflation rebounded in April, with the annual increase in core prices accelerating to its highest level since 2013.

The Wage Price Index (WPI) grew by 1.0 per cent in the December quarter, a slightly larger increase than had been seen in recent quarters, with the index 3.6 per cent higher over the year (Graph 58).

When Apple released the iPhone Plus models at the end of 2014 with the launch of the iPhone 6 Plus, it increased the price of the larger 5.5» screen model by $ 120 over the base 4.7» screen model, its first experiment with price segmentation.

To quote the report: «The three cities with the largest cumulative price increases since January 2000 are all in California: Los Angeles (138 %), San Francisco (116 %) and San Diego (115 %).»

If a sufficiently large subsidy is combined with carbon pricing, then overall average costs for a sector need not increase.

Analyst Sterling Auty initiated coverage of the company with an Overweight rating and a price target of $ 18, saying that MSS was a large market that is witnessing increasing interest from enterprise customers.

Metals X, Australia's largest tin mining company, is defying a two - year slump in prices with plans to increase output by about 14 per cent.

Every union worker is a capitalist selling his labor and attempting to increase the price he can charge for his labor by creating a larger unit of labor to bargain with.

Nomad Foods, Europe's largest frozen food producer, has reported a 1.5 % increase in revenue to $ 1.957 billion with organic revenue growth of 3.9 %, driven by 2.7 % growth in volume / mix and 1.2 % growth in price, for the twelve months ended December 31, 2017.

Even the Nigerian government had to postpone its $ 1billion Eurobond which was slated for 2016 to 2017 when a better investment environment had begun to emerge with rising oil prices, larger foreign reserves, a new economic policy document and CBN policy refinements which have significantly increased the supply of foreign currency and narrowed the gap between the various exchange rates.»

The report that landed on Sunday drew a few broad conclusions: pricing is opaque; quality and cost aren't always correlated; increased market - share often increases costs; cost - shifting — which is when hospitals with large Medicaid populations try to make up for that by charging more money to commercial insurers — doesn't happen that often.

The brain like every other human tissue is made up of and utilizes protein, so we do have to eat enough protein while the brain is growing and a small amount for daily operation, but the major metabolic price of our larger brains is the large increase in the percentage of total calories used by our brains compared to animals with smaller brain to body weight ratio.

Once again, while this increases the benefits of 529s at the bottom in a targeted manner, it comes with a hefty price - tag, and, unless the credits were quite large, is unlikely to move the needle on promoting school choice.

At some point, the ever - larger - trucks trend was sure to leave a lot of truck buyers lacking either the desire to drive such large beasts or the funds to purchase them, because with size increases also came price increases.

Not surprisingly, many truck owners don't want to deal with steep price increases, large / bulky size or poor fuel economy, and wanted something more practical.

While none of garden - variety models score the cooling, suspension and track certification upgrades shared across the newly - announced Motorsport, Magnum and Director varieties, Holden has introduced more equipment to its large sedan, a move that coincides with increased pricing.

So what does this massive price increase will bring you as an owner... firstly a totally different car, most of the exterior parts have been replaced with highly modified, totally redesigned units, mostly made from lightweight carbon fiber which actually lowers the overall weight of the Avanti Rosso with 80 kg, and that includes that massive, fixed rear wing and those large intakes above the rear wheels.

With our large e-Book catalog, Vistaar's technology will enable us to be more market and data driven in our pricing approach and in turn increase sales for our authors and our partners.

Author may purchase first order of his / her softcover edition for 50 % off list price (subsequent orders at least 30 % off list, but discount increases with larger orders)

It also comes at a very reasonable price, has the newest and best e-Ink Pearl screen with increased contrast, is very small and light (only 8.5 ounces), the battery lasts for a month, and Amazon has the world's largest e-book store, with over 750,000 titles.

The main reasons for people buying e-books online are possibly lower prices, increased comfort (as they can buy from home or on the go with mobile devices) and a larger selection of titles.

«Total stock» funds invest in a combination of small, mid-size, and large companies with varying degrees of value (meaning they focus on paying dividends) and growth (meaning they focus on increasing the price of their stock).

Graham also felt that the market responds more quickly with a price increase when an improvement is shown for a large firm than a small firm.

Katsuyama, with all of the resources of a longstanding Canadian bank, couldn't understand why his large pending trades no longer could be made without an immediate reaction of the markets (increasing prices).

Despite economic challenges, home prices in the fourth quarter remained stable in the province's largest cities, with the aggregate price of a home in Saskatoon down 0.4 % year - over-year to $ 366,933, while the aggregate price of a home in Regina increased 2.6 % to $ 340,684.

With tuition prices increasing, though, it may not mean that students will pay less for their education because many will have to take out larger loans.

With stocks at currently high multiples on normalized earnings, that type of scenario would probably increase the odds off a deep recession and induce a much larger decline in stock prices.

Our findings are consistent with those of Holderness and Sheehan (1985), who document significant price increases for firms targeted by «notorious» corporate raiders of the late 1970s and early 1980s, and also with those of Bethel, Liebeskind, and Opler (1998), who show similar results for firms targeted by individuals, rather than corporate or institutional large shareholders.

For an inverse ETF, stock returns would be positively correlated with volatility shocks — for example, large price declines in the underlying lead to large price increases in the inverse ETF.

Longer - term investors are in a position to allocate a larger portion of their portfolio to higher - risk investments like stocks than shorter - term investors because a longer time horizon is associated with lower volatilityVolatility The rate at which the price of a security increases or decreases for a given set of returns.

Historically, market tops can occur after the major market averages move into new high ground and show several days of large and increased volume with either poor price progress or actual declines in the averages.

Large private swimming pool with Solar Heating providing upto 3C increase in water temperature (optional electric heated pool at extra price), many private balconies and terraces and a covered gazebo with seating for 10 people and outside kitchen BBQ, table and chairs.

However, this $ 199.99 base price for the holidays, combined with an unexpectedly large number of software announcements for the PSVR at E3 of this year and last night's Game Awards, will only increase Sony's lead in VR.

[1] CO2 absorbs IR, is the main GHG, human emissions are increasing its concentration in the atmosphere, raising temperatures globally; the second GHG, water vapor, exists in equilibrium with water / ice, would precipitate out if not for the CO2, so acts as a feedback; since the oceans cover so much of the planet, water is a large positive feedback; melting snow and ice as the atmosphere warms decreases albedo, another positive feedback, biased toward the poles, which gives larger polar warming than the global average; decreasing the temperature gradient from the equator to the poles is reducing the driving forces for the jetstream; the jetstream's meanders are increasing in amplitude and slowing, just like the lower Missippi River where its driving gradient decreases; the larger slower meanders increase the amplitude and duration of blocking highs, increasing drought and extreme temperatures — and 30,000 + Europeans and 5,000 plus Russians die, and the US corn crop, Russian wheat crop, and Aussie wildland fire protection fails — or extreme rainfall floods the US, France, Pakistan, Thailand (driving up prices for disk drives — hows that for unexpected adverse impacts from AGW?)

While the cost is not prohibitive — the price increases with size, with a pack of the five largest bags costing $ 10 — it's certainly enough to moderate what people throw out.

Here's a few reasons why: 1) Low oil prices increase the imperative for OPEC and other countries with large oil reserves to invest in developing CDR solutions.

We return to the questions posed earlier: with fuel costs already their single largest expense, why should fuel price increases spur changes in shipping and aviation designs, equipment and practices?