Not exact matches
She also plays an active part in the Trevor Project and has worked
with the L.A Gay & Lesbian
Center concerning homeless LGBT youth, has conducted fundraising for Susan G. Komen in honor of October being Breast
Cancer Awareness month and recently
led this year's 30th annual Aids Walk Los Angeles, cutting the starting ribbon for over 25,000 walkers.
That's how Charles Sawyers, a 2009 Lasker Award winner and chair of human oncology and pathogenesis at Memorial Sloan - Kettering
Cancer Center in New York City, made the connection
with Bristol Myers Squibb (BMS) that
led to second - generation treatments for chronic myeloid leukemia (CML).
And a team
led by Moss and U. of C. Medical
Center assistant professor of medicine Patrick Singleton as well as other groups, have also given drugs that block opioid receptors to mice
with cancer.
«These findings suggest that many men
with intermediate risk prostate
cancer can be well managed with seed implant alone and do not require the addition of external beam radiation,» said Bradley Prestidge, MD, lead author of the study and Medical Director of the Bon Secours Cancer Institute at DePaul Medical Center in Norfolk, Vir
cancer can be well managed
with seed implant alone and do not require the addition of external beam radiation,» said Bradley Prestidge, MD,
lead author of the study and Medical Director of the Bon Secours
Cancer Institute at DePaul Medical Center in Norfolk, Vir
Cancer Institute at DePaul Medical
Center in Norfolk, Virginia.
«Prior studies have suggested that poor baseline mental health can
lead to more significant postoperative complications possibly due to impaired immune response associated
with higher levels of stress,» explained Scott M. Gilbert, MD, MS, of the H. Lee Moffitt
Cancer Center, Tampa, FL. «This may delay both wound healing and the ability to fight infection in the postoperative state, for example.
Led by associate professor of pathology and Yale
Cancer Center member Don Nguyen, PhD, the researchers analyzed RNA from patients
with disease that was limited to the lungs as well as
cancers that had spread.
«This study demonstrates that targeted fusion - guided biopsy could significantly enhance our ability to identify patients
with high - risk prostate
cancers that need more aggressive treatment,» says
lead author Mohummad Minhaj Siddiqui, MD, assistant professor of surgery at the University of Maryland School of Medicine and director of urologic robotic surgery at the University of Maryland Marlene and Stewart Greenebaum
Cancer Center.
The realization that «
cancer is complicated, and no single institute, country, or even continent would be able to deal
with it,»
led to the Stockholm Declaration, a commitment to join forces signed by the directors of 18 European
cancer centers.
«One criticism of the PARP drugs is they are not active in patients who have developed resistance to other therapies, but we found veliparib appears to be effective in some platinum - resistant patients
with recurrent or persistent disease,» said Robert L. Coleman, MD,
lead author of the study and professor and vice chair of clinical research at the University of Texas MD Anderson
Cancer Center, Houston.
«The phi test helps physicians distinguish prostate
cancer from benign conditions by utilizing three different PSA markers (PSA, freePSA and p2PSA) as part of a sophisticated algorithm to more reliably determine the probability of
cancer in patients
with elevated PSA levels,» said Kevin Slawin, MD, director, Vanguard Urologic Institute at Memorial Hermann Medical Group, clinical professor of Urology at Baylor College of Medicine and director of Urology, Memorial Hermann Hospital ‐ Texas Medical
Center, who performed some of the key research that
led to the development of the phi test and who also began using the test in February.
Other main contributors include Thomas Milner, professor of biomedical engineering in UT Austin's Cockrell School of Engineering and his lab members; Jialing Zhang, research associate at the Eberlin Lab at UT Austin who
led the experimental work
with other lab members; Anna Sorace, assistant professor at UT Austin's Dell Medical School; Chandandeep Nagi and Wendong Yu, professors of pathology at Baylor College of Medicine, and Jinsong Liu, professor of pathology at University of Texas MD Anderson
Cancer Center.
The immunotherapy drug pembrolizumab — already FDA - approved for other forms of
cancer - has been found to be effective in patients with metastatic triple negative breast cancer, according to an international clinical trial led by NYU Langone's Perlmutter Cancer C
cancer - has been found to be effective in patients
with metastatic triple negative breast
cancer, according to an international clinical trial led by NYU Langone's Perlmutter Cancer C
cancer, according to an international clinical trial
led by NYU Langone's Perlmutter
Cancer C
Cancer Center.
A neuro - oncology research team at Dartmouth's Norris Cotton
Cancer Center,
led by the Director Mark A. Israel, MD
with first author Gilbert J. Rahme, PhD, recently identified the transcription factor Id4 as a suppressor of tumor cell invasion in glioblastoma.
Summers and the research team,
led by Dr. Mike Jensen at the Ben Towne
Center for Childhood
Cancer Research at Seattle Children's Research Institute, are opening PLAT - 04 after discovering that of the patients who relapsed in the PLAT - 02 trial, approximately 40 percent of them relapsed with a leukemia that evolved to circumvent the CAR T cells that were reprogrammed to detect and destroy c
Cancer Research at Seattle Children's Research Institute, are opening PLAT - 04 after discovering that of the patients who relapsed in the PLAT - 02 trial, approximately 40 percent of them relapsed
with a leukemia that evolved to circumvent the CAR T cells that were reprogrammed to detect and destroy
cancercancer.
«The compelling results seen in this global study provide unequivocal evidence supporting the clinical utility of Oncotype DX to risk - stratify patients
with early stage breast
cancer, and indicate that the findings are generalizable to everyday clinical practice,» said lead author Joseph A. Sparano, MD, vice-chairman of medical oncology at Montefiore Einstein Center for Cancer Care, and professor of medicine and of obstetrics, gynecology, women's health at Albert Einstein College of Med
cancer, and indicate that the findings are generalizable to everyday clinical practice,» said
lead author Joseph A. Sparano, MD, vice-chairman of medical oncology at Montefiore Einstein
Center for
Cancer Care, and professor of medicine and of obstetrics, gynecology, women's health at Albert Einstein College of Med
Cancer Care, and professor of medicine and of obstetrics, gynecology, women's health at Albert Einstein College of Medicine.
Jeroen Roelofs, assistant professor in the Division of Biology and a research affiliate
with the university's Johnson
Cancer Research
Center,
led a study on a specific step in the assembly of proteasomes.
No one is more pleased
with the achievement — a decade in the making — than Samuel Danishefsky, a biological chemist at the Memorial Sloan - Kettering
Cancer Center in New York, who
led the team.
To this end Dr. Linding is currently
leading high - level, strategic, multidisciplinary studies of signaling network dynamics driving
cancer metastasis in collaboration with other labs at Harvard, Yale, The Jackson Laboratory, Memorial Sloan Kettering Cancer Center, MIT, and
cancer metastasis in collaboration
with other labs at Harvard, Yale, The Jackson Laboratory, Memorial Sloan Kettering
Cancer Center, MIT, and
Cancer Center, MIT, and BRIC.
In a randomized, phase 2 multi-
center clinical study,
led by Manisha Shah, MD of The Ohio State University Comprehensive
Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), investigators tested the effectiveness of the targeted therapy drug, dabrafenib (pronounced «da bRAF e nib» and marketed as Tafinlar), given alone compared with the same drug given in combination with trametinib (pronounced «tra ME ti nib,» marketed at MeKinist) to treat a subset of advanced papillary thyroid cancer patients with B - raf muta
Cancer Center — Arthur G. James
Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), investigators tested the effectiveness of the targeted therapy drug, dabrafenib (pronounced «da bRAF e nib» and marketed as Tafinlar), given alone compared with the same drug given in combination with trametinib (pronounced «tra ME ti nib,» marketed at MeKinist) to treat a subset of advanced papillary thyroid cancer patients with B - raf muta
Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), investigators tested the effectiveness of the targeted therapy drug, dabrafenib (pronounced «da bRAF e nib» and marketed as Tafinlar), given alone compared
with the same drug given in combination
with trametinib (pronounced «tra ME ti nib,» marketed at MeKinist) to treat a subset of advanced papillary thyroid
cancer patients with B - raf muta
cancer patients
with B - raf mutations.
People
with stage III colon
cancer who regularly eat nuts are at significantly lower risk of cancer recurrence and mortality than those who don't, according to a new, large study led by researchers at Yale Cancer C
cancer who regularly eat nuts are at significantly lower risk of
cancer recurrence and mortality than those who don't, according to a new, large study led by researchers at Yale Cancer C
cancer recurrence and mortality than those who don't, according to a new, large study
led by researchers at Yale
Cancer C
Cancer Center.
Data collected during a long - term health study provides additional evidence for a link between increased risk of
cancer in individuals with advanced gum disease, according to a new collaborative study led by epidemiologists Dominique Michaud at Tufts University School of Medicine and Elizabeth Platz of the Johns Hopkins Bloomberg School of Public Health and Kimmel Cancer C
cancer in individuals
with advanced gum disease, according to a new collaborative study
led by epidemiologists Dominique Michaud at Tufts University School of Medicine and Elizabeth Platz of the Johns Hopkins Bloomberg School of Public Health and Kimmel
Cancer C
Cancer Center.
«It's incredibly encouraging to find possible new options for patients
with an aggressive
cancer like triple negative breast cancer, and that studies conducted by separate teams at leading institutions agree on the implications of the findings,» said Alan Ashworth, PhD, FRS, president of UCSF Helen Diller Family Comprehensive Cancer Center, and former CEO of th
cancer like triple negative breast
cancer, and that studies conducted by separate teams at leading institutions agree on the implications of the findings,» said Alan Ashworth, PhD, FRS, president of UCSF Helen Diller Family Comprehensive Cancer Center, and former CEO of th
cancer, and that studies conducted by separate teams at
leading institutions agree on the implications of the findings,» said Alan Ashworth, PhD, FRS, president of UCSF Helen Diller Family Comprehensive
Cancer Center, and former CEO of th
Cancer Center, and former CEO of the ICR.
«Over the past several years,
with advances in technology, radiation to only the surgical bed of the resected lesion has become of interest,» said Anita Mahajan, MD, professor of radiation oncology at MD Anderson
Cancer Center in Houston and
lead author of the study.
By combining two modalities of imaging, investigators from Norris Cotton
Cancer Center at Dartmouth,
led by Keith Paulsen, PhD
with first author Michael Mastanduno and collaborators from Xijing Hospital in Xian, China, demonstrated that a dual breast exam using MRI and Near Infrared Spectral Tomography (NIRST) is feasible and more accurate than MRI alone.
«Our case studies showed similar survival
with the use of stereotactic radiation therapy compared
with surgery,» said
lead author Dr. Raquibul Hannan, Assistant Professor of Radiation Oncology and co-leader of the Kidney
Cancer Program at the Harold C. Simmons Comprehensive
Cancer Center.
The researchers,
led by Professor Bernd Pichler at the Werner Siemens Imaging
Center, worked
with dermatologists, pathologists and immunologists at the University hospitals and at the German Consortium for Translational
Cancer Research.
The research team is
led by Carl June, MD, the Richard W. Vague Professor in Immunotherapy in the department of Pathology and Laboratory Medicine and director of Translational Research in the Abramson
Cancer Center, along
with David Porter, MD, the Jodi Fisher Horowitz Professor in Leukemia Care Excellence and director of Blood and Marrow Transplantation in the Abramson
Cancer Center.
«These findings clearly point to the very important role that health care providers can play in increasing coverage
with this safe and effective vaccine,» said
lead author Linda M. Niccolai, Ph.D., associate professor in the school's Department of Epidemiology of Microbial Diseases and member of the
Cancer Prevention and Control Program of the Yale
Cancer Center.
One report, focusing on clinical trial patients
with advanced kidney
cancer treated with checkpoint inhibitors, is from scientists at Dana - Farber Cancer Institute and the Broad Institute of MIT and Harvard, led by Eliezer Van Allen, MD, of Dana - Farber and the Broad, and Toni Choueiri, MD, director of the Lank Center for Genitourinary Oncology at Dana - F
cancer treated
with checkpoint inhibitors, is from scientists at Dana - Farber
Cancer Institute and the Broad Institute of MIT and Harvard, led by Eliezer Van Allen, MD, of Dana - Farber and the Broad, and Toni Choueiri, MD, director of the Lank Center for Genitourinary Oncology at Dana - F
Cancer Institute and the Broad Institute of MIT and Harvard,
led by Eliezer Van Allen, MD, of Dana - Farber and the Broad, and Toni Choueiri, MD, director of the Lank
Center for Genitourinary Oncology at Dana - Farber.
«In addition to having a higher prevalence of triple - negative breast
cancers than Caucasian women — something that has been documented in previous studies — we found that African American women
with breast
cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor biology,» says Tanya Keenan, MD, of the MGH Cancer Center, lead author of the
cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor biology,» says Tanya Keenan, MD, of the MGH
Cancer Center, lead author of the
Cancer Center,
lead author of the study.
«
With head and neck cancer, we often clear patients of cancer only to see it come back with deadly consequences a few years later,» said lead author Julie Bauman, M.D., M.P.H., co-director of the UPMC Head and Neck Cancer Center of Excelle
With head and neck
cancer, we often clear patients of cancer only to see it come back with deadly consequences a few years later,» said lead author Julie Bauman, M.D., M.P.H., co-director of the UPMC Head and Neck Cancer Center of Excel
cancer, we often clear patients of
cancer only to see it come back with deadly consequences a few years later,» said lead author Julie Bauman, M.D., M.P.H., co-director of the UPMC Head and Neck Cancer Center of Excel
cancer only to see it come back
with deadly consequences a few years later,» said lead author Julie Bauman, M.D., M.P.H., co-director of the UPMC Head and Neck Cancer Center of Excelle
with deadly consequences a few years later,» said
lead author Julie Bauman, M.D., M.P.H., co-director of the UPMC Head and Neck
Cancer Center of Excel
Cancer Center of Excellence.
The study was
led by UCLA's Jonsson Comprehensive
Cancer Center member Dr. Joanne Weidhaas in collaboration
with colleagues at the NRG Oncology RTOG.
«There has been a great deal of debate about the effectiveness of bevacizumab in treating patients
with glioblastoma,» says
lead author Derek Johnson, M.D., a neuro - oncologist at Mayo Clinic
Cancer Center.
A group
led by Eleanor Rogan, a
cancer researcher at the University of Nebraska Medical
Center in Lincoln, took samples of healthy breast tissue from women
with and without
cancer and measured the amounts of estrogen derivatives.
A multi-institutional international study
led by scientists at The University of Texas MD Anderson
Cancer Center has revealed new information about how molecules called long non-coding RNAs (lncRNA) interact
with HIF - 1, a signaling pathway that is overexpressed in many
cancers.
A multi-
center study
led by Fred Hutchinson
Cancer Research Center has found that high - dose supplementation with both the trace element selenium and vitamin E increase the risk of high - grade prostate c
Cancer Research
Center has found that high - dose supplementation
with both the trace element selenium and vitamin E increase the risk of high - grade prostate
cancercancer.
«We already know that coordinated, patient -
centered palliative care improves care quality, enhances survival, and reduces costs for persons
with cancer,» said R. Sean Morrison, MD, Director of the National Palliative Care Research
Center and Professor of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai and
lead author of the study.
«We urgently need markers to predict which therapies are going to be effective and which will not be effective in individual patients
with advanced prostate
cancer,» said lead study author Emmanuel Antonarakis, MD, an assistant professor of oncology and urology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins in Baltimore, Md. «AR - V7 testing may be extremely valuable in guiding treatment decisions for men with hormone - resistant disease in the near future.&
cancer,» said
lead study author Emmanuel Antonarakis, MD, an assistant professor of oncology and urology at the Sidney Kimmel Comprehensive
Cancer Center at Johns Hopkins in Baltimore, Md. «AR - V7 testing may be extremely valuable in guiding treatment decisions for men with hormone - resistant disease in the near future.&
Cancer Center at Johns Hopkins in Baltimore, Md. «AR - V7 testing may be extremely valuable in guiding treatment decisions for men
with hormone - resistant disease in the near future.»
«We wanted to see whether very - large - scale screening across a diverse collection of
cancer cell lines and a large number of drugs could yield new combinations for patients with cancer,» says Adam Friedman, MD, PhD, of the CBRC and the MGH Cancer Center, who led the
cancer cell lines and a large number of drugs could yield new combinations for patients
with cancer,» says Adam Friedman, MD, PhD, of the CBRC and the MGH Cancer Center, who led the
cancer,» says Adam Friedman, MD, PhD, of the CBRC and the MGH
Cancer Center, who led the
Cancer Center, who
led the study.
«Historically, when treating early lung
cancer with radiotherapy, progression at the site of the primary tumor was the most common failure resulting in suffering and death,» said
lead study author Robert Timmerman, MD, professor and vice chair of the department of radiation oncology at the University of Texas Southwestern Medical
Center in Dallas.
«More and more patients are being cured of lung
cancer,
with both surgery and radiation as good treatment options,» said
lead author Nirav S. Kapadia, MD, of Dartmouth - Hitchcock Medical
Center in New Hampshire.
The study,
led by Deborah Armstrong at the Johns Hopkins Kimmel
Cancer Center in Baltimore, Maryland, builds upon evidence from eight other clinical trials showing an overall survival benefit of approximately one year for women treated with IP chemotherapy after «optimal debulking» — surgery to remove most, if not all, of the cancer in the ab
Cancer Center in Baltimore, Maryland, builds upon evidence from eight other clinical trials showing an overall survival benefit of approximately one year for women treated
with IP chemotherapy after «optimal debulking» — surgery to remove most, if not all, of the
cancer in the ab
cancer in the abdomen.
A team
led by epidemiologist Larry Clark of the Arizona
Cancer Center in Tucson had observed lower rates of skin cancer among people with high levels of sel
Cancer Center in Tucson had observed lower rates of skin
cancer among people with high levels of sel
cancer among people
with high levels of selenium.
Taking the focus off pain management and specific post-treatment symptoms, and putting it on quality of life defined as «active engagement,» a team from Dartmouth's Norris Cotton
Cancer Center, led by Mark T. Hegel, PhD with first - author Kathleen D. Lyons, ScD, established and tested a new paradigm for working with breast cancer surv
Cancer Center,
led by Mark T. Hegel, PhD
with first - author Kathleen D. Lyons, ScD, established and tested a new paradigm for working
with breast
cancer surv
cancer survivors.
Stahlberg currently
leads high - performance computing at the Frederick National Laboratory, working
with the National
Cancer Institute
Center for Biomedical Informatics and Information Technology.
This helps to relieve some of the stress new patients and their families may experience
leading up to that first appointment
with a
Cancer Center doctor.
Based on our findings, the occurrence of
cancer is much higher in adults over 75 years of age compared
with the proportion of patients in this age group who enroll in clinical trials,» said
lead study author Bindu Kanapuru, MD, medical officer in the Division of Hematology Products, Office of Hematology and Oncology Products in the US Food and Drug Administration's (FDA)
Center for Drug Evaluation and Research, who presented the results at the 59th American Society of Hematology (ASH) Annual Meeting and Exposition, held December 9 — 12 in Atlanta.
In a recent multi-institutional phase II trial of Onyx - 015
led by investigators at University of Texas M.D. Anderson
Cancer Center, 30 patients with advanced head and neck cancer, most of whom had failed surgery or radiation therapy, were tr
Cancer Center, 30 patients
with advanced head and neck
cancer, most of whom had failed surgery or radiation therapy, were tr
cancer, most of whom had failed surgery or radiation therapy, were treated.
«The primary goal of GEP testing is to identify patients at high recurrence risk who will benefit from chemotherapy, while allowing patients
with a low recurrence risk to forego chemotherapy, potentially offsetting the test costs
with savings from reductions in chemotherapy use,» wrote authors
led by Young Chandler, PhD, of the Georgetown Lombardi Comprehensive
Cancer Center in Washington, DC.
Quizartinib inhibits FLT3 kinase activity and induced about a 50 % composite response rate among patients
with FLT3 - ITD mutations in phase I and II studies, said
lead author Mahesh Swaminathan, MD of the University of Texas MD Anderson
Cancer Center in Houston.