Mutations in E-cadherin (CDH1) were frequent across subtypes but correlated almost perfectly
with lobular tumors.
Not exact matches
Growth and development of the mammary tissues begins at around weeks three and four of gestation,
with specific ductal branching and
lobular formation.
With that, investigators say the alterations in the ERBB2 gene strongly associate with pleomorphic lobular breast cancer but not the classic form of the dise
With that, investigators say the alterations in the ERBB2 gene strongly associate
with pleomorphic lobular breast cancer but not the classic form of the dise
with pleomorphic
lobular breast cancer but not the classic form of the disease.
Utilizing the invasive breast cancer data set of 962 cases in The Cancer Genome Atlas, all breast cancers
with alterations in the CDH1 gene (that gives instructions to make a protein that causes cancer cells to stick to one another and defines
lobular breast cancers) were identified.
PELOPS: Palbociclib and Endocrine Therapy for
Lobular Breast Cancer Preoperative Study: A Randomized Phase II Study of Palbociclib
with Endocrine Therapy versus Endocrine Therapy Alone for Invasive
Lobular Carcinoma and Invasive Ductal Carcinoma
Ultrasound was found to be inferior for detecting axillary node metastasis in patients
with invasive
lobular carcinoma compared
with invasive ductal carcinoma.
Hepatitis was markedly enhanced in immunized Prf1 − / − mice compared
with control mice,
with significantly more inflammatory
lobular infiltrates (Fig. 1E).
The tempo and degree of
lobular involution varies considerably among women, but the frequency and extent of involution increases
with aging (68).