Sentences with phrase «with low impact development»

Not exact matches

Actual results, including with respect to our targets and prospects, could differ materially due to a number of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and lower margins; our ability to lower costs; the risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix; risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs, including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks resulting from the concentration of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory levels, all of which could negatively affect product demand; the risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products; risks associated with ongoing litigation; and other factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Alternative protein sources may include the use of by - products currently viewed as waste or the development of new protein sources from plants, lower order animals, or single - cell organisms with a lower environmental impact compared with typical animal - based protein sources.

We are very excited at the opportunity to benefit from Mass Audubon's experience with local zoning regulations, and will greatly appreciate their help in creating new subdivision regulations that will encourage the use of low - impact development and green infrastructure,» said Hudson's Conservation Agent and Planner Pam Helinek.

Low Impact Development (LID) is a category of green infrastructure that works with nature to manage stormwater and decrease the impact of development on surface and groundImpact Development (LID) is a category of green infrastructure that works with nature to manage stormwater and decrease the impact of development on surface and gDevelopment (LID) is a category of green infrastructure that works with nature to manage stormwater and decrease the impact of development on surface and groundimpact of development on surface and gdevelopment on surface and groundwater.

We are working within the watershed to find cost - effective stormwater solutions, with a focus on Low Impact Development, or LID, which works with nature rather than against it.

The early years are tremendously important in a child's development, and right now the way we deal with the education of children in those years is very low - impact, to the point of being non-existent, in many places.

Excerpt: «With healthier outcomes with more parks, lowered impact development, light rail, mitigated sediment management with mechanical conveyance to above reservoir, Los Angeles River and Sunland - Tujungsa watershed revitalization, net - zero energy building, transit - oriented development, mixed use, pedestrian - friendly communities.&raWith healthier outcomes with more parks, lowered impact development, light rail, mitigated sediment management with mechanical conveyance to above reservoir, Los Angeles River and Sunland - Tujungsa watershed revitalization, net - zero energy building, transit - oriented development, mixed use, pedestrian - friendly communities.&rawith more parks, lowered impact development, light rail, mitigated sediment management with mechanical conveyance to above reservoir, Los Angeles River and Sunland - Tujungsa watershed revitalization, net - zero energy building, transit - oriented development, mixed use, pedestrian - friendly communities.&rawith mechanical conveyance to above reservoir, Los Angeles River and Sunland - Tujungsa watershed revitalization, net - zero energy building, transit - oriented development, mixed use, pedestrian - friendly communities.»

«This Agreement, in enhancing the implementation of the [2015 United Nations Framework Convention on Climate Change], including its objective, aims to strengthen the global response to the threat of climate change, in the context of sustainable development and efforts to eradicate poverty, including by: (a) Holding the increase in the global average temperature to well below 2 °C above pre-industrial levels and pursuing efforts to limit the temperature increase to 1.5 °C above pre-industrial levels, recognizing that this would significantly reduce the risks and impacts of climate change; (b) Increasing the ability to adapt to the adverse impacts of climate change and foster climate resilience and low greenhouse gas emissions development, in a manner that does not threaten food production; and (c) Making finance flows consistent with a pathway towards low greenhouse gas emissions and climate - resilient development.

The positive impact of sustained high levels of maternal responsivity from toddlerhood through middle childhood was true even for children with more autistic symptoms and lower nonverbal cognitive development levels.

Suburban development may present barriers to physical activity, leading to negative health impacts that counterbalance health gains associated with lower exposure to PM.

Approximately equal numbers of women and men enter and graduate from medical school in the United States and United Kingdom.1 2 In northern and eastern European countries such as Russia, Finland, Hungary, and Serbia, women account for more than 50 % of the active physicians3; in the United Kingdom and United States, they represent 47 % and 33 % respectively.4 5 Even in Japan, the nation in the Organisation for Economic Co-operation and Development with the lowest percentage of female physicians, representation doubled between 1986 and 2012.3 6 However, progress in academic medicine continues to lag, with women accounting for less than 30 % of clinical faculty overall and for less than 20 % of those at the highest grade or in leadership positions.7 - 9 Understanding the extent to which this underrepresentation affects high impact research is critical because of the implicit bias it introduces to the research agenda, influencing future clinical practice.10 11 Given the importance of publication for tenure and promotion, 12 women's publication in high impact journals also provides insights into the degree to which the gender gap can be expected to close.

Amie's research interests focus on the prevention of problem behaviors in youth, with a particular focus on identifying malleable risk and protective factors associated with the development of problem behaviors, and examining the impact of evidence - based interventions on reducing or preventing the development of such behaviors within low - income populations.

Finally, the PROSPER Act's inclusion of IMPACT Grants supports innovation by encouraging the creation, development, implementation, replication, or scaling of evidence - based practices for low - income students, students with disabilities, and first - generation students.

Nevertheless, Committee members found the evidence on the impact of high - quality pre-K and third - grade reading so compelling that members recommended making difficult choices to prioritize these areas even at the potential expense of other K - 12 funding priorities, such as lowering class sizes, investing in teacher professional development, and improving classroom technology, that have not been shown to correlate as strongly with improved student outcomes, particularly for high - need students.

Previous work on the impact of philanthropy in education terms these types of status quo investments as «lower leverage» grants, which can include funding for efforts in professional development, unrestricted or general purpose grants to schools, or special - purpose grants to fund a particular program or activity (e.g. arts enrichment).4 The contrasting approach — the «higher leverage» investment — is investment with the potential to exert systemic influence on public education, which can be divided into two broad categories: 5

Table 2 Charters with Lowest Administrative Costs Per pupil Charter Enrollment Administration / Pupil Flagstaff Montessori, LLC 257 $ 0 Premier Charter High School 3,217 $ 128 Ed Ahead, Inc. 82 $ 240 Noah Web Pima 281 $ 286 The Odyssey Preparatory Academy, Inc. 2,641 $ 319 Akimel O'Otham Pee Posh Charter School 181 $ 330 James Madison Preparatory School 184 $ 373 Educational Impact, Inc. 201 $ 393 EDUPRIZE SCHOOLS LLC 3,630 $ 417 Hillcrest Academy 106 $ 432 Montessori Education Centre — Charter School 462 $ 436 El Centro for the Study of Primary and Secondary Education, Inc. 63 $ 537 CAFA, Inc., dba Learning Foundation Performing Arts Alta Mesa 252 $ 538 Friendly House Inc. 397 $ 550 Self Development Charter School 461 $ 555 Carden of Tucson, Inc 129 $ 557 Global Renaissance Academy of Distinguished Education 93 $ 563 Satori, Inc. 169 $ 605 Ridgeline Academy 609 $ 633 Happy Valley School Inc. 464 $ 670 Empower College Prep 377 $ 680 CAFA, Inc. 214 $ 682 Heritage Academy, Inc. 650 $ 691 P.L.C. CHARTER SCHOOLS 1.134 $ 711 Benchmark School, Inc. 417 $ 736 Horizon Community Learning Center 799 $ 753 American Basic School 880 $ 758 Pioneer Preparatory School Challenge Foundation 628 $ 769 East Valley Academy 23 $ 776 Benjamin Franklin Charter School 2,850 $ 781

The TIFIA JPO is closely monitoring the traffic volumes and toll revenues generated by the project, which are considerably lower than the forecast in 2005, and are working with the concessionaire and other lenders to evaluate the impact of these developments which will ultimately likely require financial restructuring of the project.

Digital disruption, as described in James McQuivey's book, Digital Disruption, is the use of digital resources for the specific purpose of providing more value at «a lower cost, with faster development times, and greater impact.»

The Great and Powerful Digital Disruption Digital disruption, as described in James McQuivey's book, Digital Disruption, is the use of digital resources for the specific purpose of providing more value at «a lower cost, with faster development times, and greater impact.»

Klein is a recognized industry leader in the research, development and implementation of energy efficiency and renewable energy with noteworthy projects in energy storage, smart grid, demand response, and tidal, geothermal, wind, solar and low impact hydro generation.

This will encourage development of sustainable, low - carbon fuels that avoid conflict with food production and minimize harmful environmental impacts.

Climate Finance is urgently needed to enable developing countries to deal with the impacts of climate change, build climate resilience, and shift to low carbon development pathways.

This analytical document suggests that while the Clean Development Mechanism (CDM) has been successful with mitigating the impacts of large - scale industrial projects, small - scale community - based projects, such as those in the waste management sector have been overlooked due to their low mitigation potential.

Development of high voltage direct current cables and transmission systems — Although initial loss of electricity of DC cables is higher than for AC, there is no incremental loss of electricity as the length of the cable increases, making it possible to build offshore wind farms in very windy areas and transmit the energy over vast distances to areas with poor wind regimes, and to combine wind generators from different areas to reduce the impact of low - wind days and the need to use backup hydrocarbons on those days

Last but not least, the development of artificial intelligence, big data and machine learning solutions will allow both the lawyers and their clients to work differently: we will become «augmented professionals», working with powerful tools at a lower cost, thereby enhancing effectiveness to identify risks and opportunities to reduce the impact on businesses.

Bradley and others, Impact of the Infant Health and Development (IHDP) on the Home Environments of Infants Born Prematurely and with Low Birthweight (see note 40).

Mild ID during pregnancy might have an impact on brain development, despite maintained normal thyroid hormone levels.19 — 22 In the UK, a longitudinal study19 found 8 - year - old children have an increased risk of being in the lowest quartile of verbal IQ, if their mothers had mild ID in early pregnancy, than children of mothers with normal iodine nutrition.

The concept of resilience and closely related research regarding protective factors provides one avenue for addressing mental well - being that is suggested to have an impact on adolescent substance use.8 — 17 Resilience has been variably defined as the process of, capacity for, or outcome of successful adaptation in the context of risk or adversity.9, 10, 12, 13, 18 Despite this variability, it is generally agreed that a range of individual and environmental protective factors are thought to: contribute to an individual's resilience; be critical for positive youth development and protect adolescents from engaging in risk behaviours, such as substance use.19 — 22 Individual or internal resilience factors refer to the personal skills and traits of young people (including self - esteem, empathy and self - awareness).23 Environmental or external resilience factors refer to the positive influences within a young person's social environment (including connectedness to family, school and community).23 Various studies have separately reported such factors to be negatively associated with adolescent use of different types of substances, 12, 16, 24 — 36 for example, higher self - esteem16, 29, 32, 35 is associated with lower likelihood of tobacco and alcohol use.

(Athena A. Drewes, PsyD, registered play therapist supervisor, director of clinical training, Astor Services for Children & Families) Advances in our understanding of the sequential nature of brain development and the impact of trauma on this development have ignited considerable interest in finding therapies that are effective with lower brain region dysfunction.

Faced with risk factors such as high poverty rates and domestic violence and low preschool enrollment, Denver is leveraging its community assets and collective impact expertise to create a trauma - informed system that supports social - emotional development.

The NCB Financial Group also works in a strategic alliance with NCB Capital Impact, a non-profit Community Development Financial Institution created under the same act of Congress as NCCB with particular focus on impacting low and moderate income communities.

In previous comment letters to the EPA on this issue, NAR recommended that the Agency not move forward with lowering the permitting thresholds, because of the fact that large office and apartment buildings could be included and be required to obtain a permit to emit CO2, which would have a detrimental impact on commercial real estate markets and economic development.