Not exact matches
In addition, cohousing coprophagic mice harboring
transplanted microbiota from discordant pairs provides an opportunity to determine which bacterial taxa invade the gut communities of cage mates, how invasion correlates
with host phenotypes, and how invasion and microbial niche are affected by human diets.
Using fecal
transplants, researchers transferred
microbiota from IBS patients
with or without anxiety into germ - free mice.
Liver cirrhosis is a leading cause of morbidity and mortality,
with complications such as HE resulting in recurrent emergency hospitalizations, irreversible brain injury, and a poor prognosis.2 - 5 There is some evidence that HE patients have a reduced relative abundance of certain beneficial gut
microbiota (e.g. Lachnospiraceae and Ruminococcaceae) and an enrichment of potentially pathogenic Enterobacteriaceae ¬ - a microbial profile that has been linked to cognitive impairment and systemic inflammation in cirrhotic patients
with HE.1 Faecal
microbiota transplants have been used successfully to correct dysbiotic conditions such as recurrent Clostridium difficile and ulcerative colitis,6 - 8 and a preliminary report suggested that FMT may be promising in the management of HE.9
They found that Harlan mice
transplanted with Jackson
microbiota copied the anti-tumor response and tumor growth of Jackson mice.
Probiotics / prebiotics / antibiotics Tacrolimus concentration to dose ratio in solid organ
transplant patients treated
with fecal
microbiota transplantation for recurrent Clostridium difficile infection.
Scientists are excited by recent success
with fecal
microbiota transplants (FMT), transfer of healthy fecal matter into ailing patients, notably those
with clostridium difficile (C. diff), a bacterial infection acquired after antibiotics, often in hospitals, that kills more than 15,000 people a year.
Like an organ
transplant, fecal
microbiota transplantation begins
with finding a donor, often a family member.
With antibiotics in particular, however, there is evidence of localized permanent extinction — in other words, some species of microorganisms never recover post-antibiotic, and can not be «reinoculated» unless you undergo the arduous and expensive process of fecal
microbiota transplant (FMT).
In this follow - up interview
with Glenn Taylor of the Taymount Clinic in the U.K., we discuss the latest developments in fecal
microbiota transplant (FMT).