Structural eye anomalies (in particular,
microphthalmia and coloboma), cataracts, intraocular calcifications, and posterior ocular findings have been reported in infants
with presumed and laboratory - confirmed prenatal ZIKV infection; however, posterior findings have been the most prevalent.21,25,28,33,35,36,41 - 43 Case series report chorioretinal atrophy, focal pigmentary mottling of the retina, and optic nerve atrophy / anomalies.28, 34,37,41 - 43,55 Series of 20 or more infants
with presumed ZIKV - associated microcephaly report ocular findings in 24 % to 55 %.28, 33,42 In one study, testing for ZIKV IgM was performed in 24 of 40 infants (60 %)
with microcephaly and the results were positive in the cerebrospinal fluid in 100 % of those tested.42 The proportion of infants
with ocular lesions did not differ in those
with and without testing.42 In that series, first trimester maternal infection and smaller head circumference significantly correlated
with the presence of abnormal ocular findings.42
Merle colored Pomeranians often deal
with deafness, ametropia, colobomas, intraocularal pressure and
microphthalmia.