The identification of quantitative trait loci (QTL) for heat tolerance in the most promising donors and tagging
these with molecular markers that could be used in selecting for the trait (s) could effectively offset the difficulty of screening cultivars in the field due to the unpredictability of heat stress occurrence during flowering.
These researchers looked for associations
with molecular markers and environmental factors, including dietary habits, physical activity, biorhythms, psychosocial characteristics, and exposure to environmental pollutants.
Six Xa genes have been tagged
with molecular markers and used to help identify new resistant lines, resulting in the release of resistant varieties in several countries.
Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in western, northern, and eastern Cambodia, 2011 - 2012: association
with molecular markers.
Current explorations into the molecular underpinnings of cell circuitry are leveraging multiple data types including expression profiling and epigenetic analysis leveraging RNA - seq and CHiP - Seq coupled
with molecular markers and cellular phenotypes.
The favorable genes or alleles will be tagged
with molecular markers for marker - assisted selection.
«Initially, the cell identifies all potential replication origins
with a molecular marker.
Not exact matches
Since older people have greater potential for improving their fitness than younger people, a follow - up study conducted by a research group headed by doctor and
molecular biologist Helmuth Haslacher from MedUni Vienna, in collaboration
with Robert Winker's team from the Health and Prevention Center of the Healthcare Institution for City of Vienna employees, took blood samples from 47 marathon runners before an ergometer test, in order to carry out laboratory tests to determine levels of analytes, including inflammatory
markers, muscle and liver parameters.
With the aid of DNA
markers, we now know which gene is responsible for which
molecular feature.
Global gene expression studies found that the LPA - treated mice shared many similar
molecular markers as those found in humans
with schizophrenia.
The researchers showed that the latest approach to epidemiology worked to track both HIV infections and levels of prostate - specific antigen, a
molecular marker associated
with prostate cancer.
A chromosome - specific BAC library was used to assemble 82 % of the chromosome into 1036 contigs that were anchored
with 1443
molecular markers, providing a major resource for genetic and genomic studies.
If patients who respond well have a particular
molecular signature, investigators can include more people
with those
markers in the trial and stop treatment for those who don't respond well.
Molecular markers — pieces of DNA that «mark» a specific gene — allow researchers to comb the genetic blueprint of a plant, match the sequence
with a certain trait using computer programs, and develop seeds.
«Our data agree
with the notion of high evolutionary rate - heterogeneity of
molecular markers in plants.
The biopsies come from patients diagnosed at the University Hospitals of Cruces and Basurto.The aim is «to find a combination of
molecular markers that will enable us to come up
with the diagnosis and prognosis of the melanoma in the most effective way possible.»
Plant breeding research elsewhere in the world has benefited from advances in genomics and
molecular markers, but plant breeding scientists in China do not work closely
with researchers in those areas, says Carl Pray, an agriculture, food, and resource economics expert at Rutgers University in New Brunswick, New Jersey, who has worked in China.
At Monsanto, the practice has become so common that, in a recent paper, the firm said «
molecular marker assisted breeding is becoming our conventional breeding process,» noting that many of its commercial crops are derived
with the process.
With the advent of more and more sophisticated ways to measure genetic variation and relatedness using
molecular markers, such as allozyme polymorphisms and DNA - based
markers, not only can individuals be tracked as to their parentage, but changes in allele patterns over time and thus the effects of evolution on populations can be «seen» in the genetic information.
The approach combines clinical factors and the
molecular markers associated
with the different medulloblastoma subtypes to guide how radiation and chemotherapy are combined
with surgery.
After 12 years of traditional breeding
with the help of
molecular markers, he has created a new rainbow - streaked tomato less prone to cracking and also endowed
with 12 disease - resistant genes.
Professor David Wraith, who led the research, said: «Insight into the
molecular basis of antigen - specific immunotherapy opens up exciting new opportunities to enhance the selectivity of the approach while providing valuable
markers with which to measure effective treatment.
Rats born of hypoxic pregnancy
with no vitamin C treatment showed increased thickening of the walls of the aorta — up to 170 % above normal — and
molecular markers of disease, such as an increase in the heart's heat shock proteins, a signal of cardiac oxidative stress.
Large - scale resequencing of the first ESTs and subsequent genotyping of single nucleotide polymorphisms in large populations expanded the available
molecular marker resources and provided a basis for examining their association
with traits of interest (Eckert et al. 2013).
The booklet discusses in detail and in simple language agricultural biotechnology as it compares
with conventional breeding, the agricultural biotechnology tools used in crops such as tissue culture and micropropagation,
molecular breeding and
marker - assisted selection, and genetic engineering and GM crops.
Working closely
with more than 200 data contributors, WWARN is able to use this powerful resource to perform pooled analyses that uncover new insights into the emergence and spread of malaria drug resistance, including evaluating the efficacy of antimalarial combination therapies (ACTs), and examining whether known
molecular markers can predict clinical outcomes.
But the new data reveals that oRGs bring a support group
with them: The cells express genes for surface
markers and
molecular signals that enhance their own ability to proliferate, the researchers found.
These goals will be achieved through collaboration
with faculty from MDL and other laboratories, and participation in both the new clinical test evaluation process overseen by the virtual
Molecular Targets and
Markers Testing Facility, and in the division's clinical laboratory test governance.
The primary tumor location was an independent prognostic
marker in patients
with RAS wild - type metastatic colorectal cancer after adjusting for age, gender, synchronous / metachronous disease, consensus
molecular subtype, and microsatellite instability and
molecular status, according to the results of an analysis (abstract 3503) of data from CALGB / SWOG 80405 presented at the 2017 American Society of Clinical Oncology (ASCO) Annual Meeting.
To address the pressing question of identifying
molecular markers, TRAC has partnered
with the MRC Centre for Genomics and Global Health to conduct large - scale genomic analyses to identify mutations associated
with ART - R.
To hunt for possible
molecular markers, researchers started
with an African strain of P. falciparum parasites that had been repeatedly exposed to artemisinin until it was able to survive high doses of the drug in the lab.
With multiyear field studies, Xue identified plant traits related to drought tolerance, which can be used by breeders to develop drought - tolerant wheat cultivars and geneticists to screen
molecular markers and speed the breeding process.
Those
with uninformative cytogenetic or
molecular markers with negative minimal residual disease at the end of induction were noted to experience the most benefit (nearly 2-fold benefit from receiving a fifth dose of chemotherapy) vs. those
with favorable cytogenetic and
molecular features who did not experience benefit from receiving a fifth dose of therapy.
December 13, 2011
Molecular markers can predict spread of cancer, guide treatment
Molecular markers found in cancer cells that have spread from a primary tumor to a limited number of distant sites can help physicians predict which patients
with metastatic cancer will benefit from aggressive, targeted radiation therapy.
If you collect fluid from inside the pelvis of women
with endometriosis, there are at least 13 different
markers of inflammation that create a
molecular signature of endometriosis.