Sentences with phrase «with mouse models of autism»

We will present data obtained with mouse models of autism, that demonstrate the utility of the system.

Not exact matches

«The successful restoration of normal function demonstrated in the mouse models suggests that if we can develop therapies to address the loss of Mecp2,» Baylor's Zoghbi says, «we may be able to reverse neurological damage in children and adults with Rett, autism and related neuropsychiatric disorders.»
A new mouse model of a genetically - linked type of autism reveals more about the role of genes in the disorder and the underlying brain changes associated with autism's social and learning problems.
Scientists at Duke Health who developed the new model also discovered that targeting a brain receptor in mice with this type of autism could ease repetitive behaviors and improve learning in some animals.
To study the relationship between autism and subplate neuron development in mice, Kanold, Nagode and their collaborators began with a well - established mouse model of autism.
In a study published earlier this year, Jiang and other collaborators at Duke described a mouse model of autism in which they deleted a prominent autism gene called SHANK3, which is mutated in 1 percent of people with the disorder.
The mouse models of autism on a normal lab diet (with a medium glycemic index) are already known to generate fewer new neurons, and some of their existing cells and neuronal connections are abnormal compared with those of normal mice.
By demonstrating that a widely used mouse model of autism does have gastrointestinal problems, and that these problems are associated with behavioral symptoms, the new research «shows us something fabulous,» says Betty Diamond, an immunologist at the Feinstein Institute for Medical Research in Manhasset, New York.
Researchers Daniel Nagode and Patrick Kanold, together with their colleagues, used a well - established mouse model of autism, which involves injecting valproic acid (VPA) on mouse embryos during day 12 of their 20 - day gestational period.
This study therefore characterizes the structural and cellular bone phenotype in a mouse model of autism that can be further utilized to investigate therapeutic avenues to treat bone fractures in children with autism.
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