Sentences with phrase «with multiple cell»

Not exact matches

Users can connect with one cell or multiple cells.

Reports from the company's bankruptcy filings indicate conversations with multiple companies that could potentially acquire the bankrupt cell and module maker.

The third order (lower scale) is common for these 2 dosing and high - multiple blood - sampling days (days 1 and 8), with each cell on the time axis representing 1 h.

My daughter's and my diagnosis with a Mast Cell Disorder has lead me to do some research into mast cell disorders and how they relate to these other diseases, especially since my daughter also has tree allergies, celiac disease and ADHD; I have EoE, environmental and other severe food allergies; and my son has a diagnosis of multiple life threatening food allergies, eczema, environmental allergies and astCell Disorder has lead me to do some research into mast cell disorders and how they relate to these other diseases, especially since my daughter also has tree allergies, celiac disease and ADHD; I have EoE, environmental and other severe food allergies; and my son has a diagnosis of multiple life threatening food allergies, eczema, environmental allergies and astcell disorders and how they relate to these other diseases, especially since my daughter also has tree allergies, celiac disease and ADHD; I have EoE, environmental and other severe food allergies; and my son has a diagnosis of multiple life threatening food allergies, eczema, environmental allergies and asthma.

Juan Carlos Izpisúa Belmonte of the Salk Institute in La Jolla, California, knew that stem cells are more useful for gene therapy than ordinary cells, because they produce multiple daughter cells with the modified genes.

Analyzing a database of nearly 800 multiple myeloma patient samples, they discovered that 162 patients with low ADAR1 levels in their tumor cells survived significantly longer over a three - year period compared to 159 patients with high ADAR1 levels.

However, Stephen Back, a neurologist at the Oregon Health and Science University in Portland, points out that there is not yet proof that myelin - producing cells are stuck in arrested development in infants with brain injuries, although this has been shown both in mice and in adults with multiple sclerosis.

They also found AXIN2 in the damaged nerve cells of adults with multiple sclerosis, a disease in which the immune system attacks myelin.

In the high magnification colorized image of atomic structure in multiple layers typical for a solar cell, the junction of a layer of the transparent hole - conducting material (primarily yellow) with an electron - conducting layer (primarily green) is shown.

Although blood cells serve multiple roles in the body and have complex interactions with other cellular materials, most synthetic blood products have aimed to just stick to the bare basics — shuttling oxygen from the lungs to different vital organs and then bringing carbon dioxide back to the lungs to be exhaled.

As a patient's BMI increases, fat cells communicate with multiple myeloma cells, researchers found.

Researchers have designed a nanoparticle - based therapy that is effective in treating mice with multiple myeloma, a cancer of immune cells in the bone marrow.

In humans, a comparison of bone marrow from 14 normal bone marrow donors, 35 multiple myeloma patients and 11 patients with a noncancerous condition called monoclonal gammopathy of undetermined significance (MGUS) showed that Runx2 levels were significantly higher in the multiple myeloma cells.

Researchers at Washington University School of Medicine in St. Louis have developed a nanotherapy that is effective in treating mice with multiple myeloma, a cancer of bone marrow immune cells.

For this analysis, 605 patients with newly diagnosed multiple myeloma and treated with continuous lenalidomide (brand name Revlimid) following autologous stem cell transplant were compared to 604 patients who were treated with placebo or no maintenance.

«Lenalidomide maintenance following autologous stem cell transplant can now be considered a standard of care for people with multiple myeloma,» says Dr. McCarthy, senior author on the meta - analysis and Principal Investigator of the U.S. study, CALGB (Alliance) 100104.

Treatment for advanced melanoma has seen success with targeted therapies — drugs that interfere with division and growth of cancer cells by targeting key molecules — especially when multiple drugs are used in combination.

Comparing the metastasized tumors with the original breast tumors, the researchers were surprised to learn that multiple, slightly genetically different cells from the original site had broken away together and established the new tumors.

To become a full - blown cancer (as opposed to a cell with a single, potentially threatening mutation — a genetic risk factor for becoming a cancer) requires the accumulation of five to ten mutations, and statistically that requires multiple rounds of cell division and selection.

PTEN tagged with multiple ubiquitin molecules can then be recognized and destroyed by the cell's protein degradation machinery.

Think sperm with multiple tails, no tails at all or in the case of one fruit fly, sperm that are nearly 6 cm long — roughly a thousand times longer than a human sperm cell.

To use these cells to develop new treatments for MS, Zack is working with Peter Calabresi, M.D., professor of neurology and director of the Johns Hopkins Multiple Sclerosis Center.

But like the medieval alchemists, today's cloning and stem cell biologists are working largely with processes they don't fully understand: What actually happens inside the oocyte to reprogram the nucleus is still a mystery, and scientists have a lot to learn before they can direct a cell's differentiation as smoothly as nature's program of development does every time fertilized egg gives rise to the multiple cell types that make up a live baby.

And each cell has thousands of connecting points to other cells with multiple branches.

If metastatic cancers are most often made up of cells with different genetic drivers, perhaps researchers should be targeting the primary tumor with multiple drugs to contain the cancer.

«The treatment of multiple myeloma has improved significantly in recent years with the introduction of therapies such as proteasome inhibitors [which interfere with tumor cells» protein - disposal system] and potent immuno - modulatory agents,» said the paper's senior author and lead investigator, Paul Richardson, MD, clinical program leader and director of clinical research at Dana - Farber's Jerome Lipper Multiple Myeloma Center, and the R.J. Corman professor at Harvard Medicalmultiple myeloma has improved significantly in recent years with the introduction of therapies such as proteasome inhibitors [which interfere with tumor cells» protein - disposal system] and potent immuno - modulatory agents,» said the paper's senior author and lead investigator, Paul Richardson, MD, clinical program leader and director of clinical research at Dana - Farber's Jerome Lipper Multiple Myeloma Center, and the R.J. Corman professor at Harvard MedicalMultiple Myeloma Center, and the R.J. Corman professor at Harvard Medical School.

«We found that these include multiple locations for nerve cells in the brainstem that innervate the heart with insulated fibres that conduct rapid impulses, causing an instantaneous cardiac response to each air - breath.»

Cell phones would thrum with multiple messages to seek shelter while local meteorologists broadcast similar warnings on television and radio.

New research led by UC San Francisco scientists has revealed that mutations in a gene linked with brain development may dispose people to multiple forms of psychiatric disease by changing the way brain cells communicate.

The scientists discovered that dinaciclib, by interfering with UPR activation, caused multiple myeloma and myeloid leukemia cells to initiate a form of cell suicide known as apoptosis when exposed to agents that induced ER stress.

«T - cell receptor therapy achieves encouraging clinical responses in multiple myeloma: NY - ESO T cell receptor therapy found to be safe, with no cytokine release syndrome cases.»

To turn these cellular LEGOs into arrays of organoids that can be used for research, Gartner's team lays down the cells in layers, with multiple sets of cells designed to stick to particular partners.

Results from a clinical trial investigating a new T cell receptor (TCR) therapy that uses a person's own immune system to recognize and destroy cancer cells demonstrated a clinical response in 80 percent of multiple myeloma patients with advanced disease after undergoing autologous stem cell transplants (ASCT).

Cells can be incubated with several sets of DNA bar codes to specify multiple allowable partners.

Dor's own group reports this week that its technique for tracing the origin of circulating DNA detected the expected type of cell death in people with pancreatic cancer, type 1 diabetes, multiple sclerosis, and brain injuries.

«Multiple myeloma patient study shows promise for natural killer cells: Phase I study included combination with high - dose chemotherapy and stem cell transplantation.»

The finding that normal fertilization can result in embryos containing cells with different parental sets of chromosomes is a new mechanism for chimerism, which was previously thought to occur only as the result of fertilization errors, for example, the fusion of multiple sperm or eggs to form an embryo.

Syndax Pharmaceuticals, Inc. («Syndax,» the «Company» or «we»)(Nasdaq: SNDX), a clinical stage biopharmaceutical company developing entinostat and SNDX - 6352 in multiple cancer indications, in collaboration with The Wistar Institute and Indiana University Melvin and Bren Simon Cancer Center, today announced the publication of a preclinical report demonstrating that entinostat, Syndax's oral, Class - I histone deacetylase inhibitor, enhances the antitumor effect of PD - 1 (programmed death receptor - 1) blockade through the inhibition of myeloid derived suppressor cells (MDSCs).

Cancer cells treated with the RNA molecules never become resistant to them because they simultaneously eliminate multiple genes that cancer cells need for survival.

If the approach also works with human cells, it could eventually lead to cell therapies for diseases like inherited leukodystrophies — disorders of the brain's white matter — and multiple sclerosis, as well as spinal cord injuries.

Yet autoimmune cells occasionally slip past this barrier, sometimes with devastating results: In multiple sclerosis (MS), for instance, these cells destroy the nerve fibers» protective sheath, crippling their victims.

Wherry, together with his colleagues in the Parker Institute for Cancer Immunotherapy at Penn, are involved in multiple checkpoint - related trials, in melanoma, lung cancer, renal cell carcinoma, and others, including combining checkpoint blockade with radiation.

Mice severely disabled by a multiple sclerosis (MS)-- like condition could walk less than two weeks following treatment with human stem cells.

Animal studies have shown that lengthy or multiple experiences with anesthesia can lead to cell death and problems with the formation of connections among brain cells.

Mutations of RGS1 are associated with several autoimmune diseases, including multiple sclerosis, and a drug targeting cell migration has been approved to treat multiple sclerosis, he notes.

«ADRCs consist of multiple cell types with multiple potential benefits,» said Timothy D. Henry, MD, MSCAI, director, division of cardiology at the Cedars - Sinai Heart Institute and the study's lead investigator.

More proof came when the researchers inhibited Udx1 with antibodies or drugs: the egg's membrane did not harden after fertilization, and multiple sperm entered, the team reports in this month's issue of Developmental Cell.

«Mice with multiple sclerosis - like condition walk again after human stem cell treatment.»

«Because Th17 cells have been linked to a number of autoimmune diseases, including multiple sclerosis, we thought our compound might inhibit Th17 cells in type 1 diabetes and possibly interfere with disease progression,» said Solt.

After much experimentation with multiple combinations, the researchers found that adding two more signals to the mix — transcription factors called ISL1 and LHX3 — turned the skin cells into spinal cord motor neurons in about 30 days.