Sentences with phrase «with myosin»

His recently published work defined the role of Rab11a and Rab8a interactions with myosin Vb in the development of severe neonatal diarrhea in children with Microvillus Inclusion Disease and he has recently published work on the phenotypes of mouse models of MYO5B KO.

This is a still image from a video showing the interaction of filamentous actin (mApple - F - tractin, purple) with myosin IIA bipolar head groups (EGFP, myosin IIA, green) at 20 - second intervals for 100 time points, as seen with high - NA TIRF - SIM.

Not exact matches

These findings suggest that the therapeutic protein was able to interact normally with its binding partners among the USH1 molecular complex (the proteins cadherin 23, protocadherin 15, myosin VIIA and harmonin), as required for the mechanoelectrical transduction apparatus of the hair bundle to function correctly.

Interestingly, Myh9 is also mutated in human head and neck cancers, and low expression of myosin IIa correlates with poor prognosis for the patient,» says Fuchs.

Force Dependent Biotinylation of Myosin IIA by α - Catenin Tagged with a Promiscuous Biotin Ligase.

Myosin - V Is Activated by Binding Secretory Cargo and Released in Coordination with Rab / Exocyst Function.

A ring composed of actin filaments and myosin motor proteins pinches the cell apart, producing two daughter cells with equal amounts of cellular components.

MYH6 encodes one form of myosin, a major component of the contractile system of the heart, and was recently associated with the function of the conduction system of the heart by studies from deCODE and others.

We applied our technique to the study of molecular motors, using myosin II from fast skeletal muscle, and to protein - DNA interaction, for the lactose repressor (LacI) interaction with DNA.

The atomic structures of the cardiac myosin motor domain, with and without bound omecamtiv mecarbil, were determined using X-ray crystallography.

Stress fi bers of Hela cell: Antibody staining with Alexa Fluor 488 (green) for actin, Alexa Fluor 568 (red) for myosin heavy chain.

The interaction occurs principally in the biosynthetic and secretory pathways (Sans et al 2001) and SAP97 provides a linkage between the AMPA receptor subunit and the microtubule - based transport mechanisms, via an interaction with the motor protein myosin VI (Wu et al 2002).

For example, clusters containing genes that are upregulated during the course of ES cell differentiation (Table 3) include in order of time of expression: cluster 30 that represents genes which take part in the formation of the three embryonic germ layers during gastrulation, i.e., Goosecoid, Cerberus like 1 homolog, Wnt3, Mesp1, Mixl1, mEomes and Even - skipped 1; cluster 15 containing molecular regulators of early mesoderm development including Bmp2, Bmp5, Msx1, Msx2, Cripto, Tbx20, Hey2, Smad6, Vegfr2 (Kdr), Foxf1 and Hand1; cluster 20, which comprises regulatory and structural genes linked to hemopoiesis such as Gata1, Nfe2, Klf1, Tie1, hemoglobins (Hba - x, Hbb - b1) and Glycophorin A; cluster 12, which is rich in genes involved in cardiac development, e.g., Mef2c, Myl4, cardiac Troponin T2, Tropomodulin 1, myosin binding protein C, Bves, Angiopoietin 1 and Angiopoietin 2; and, cluster 4, which consists mostly of genes associated with neuronal development and differentiation, for example, Neurog1, Neurog2, Olig2, Nkx6.1, Neurod4, Pou3f2, Pou3f4, Cacna2d3, Cacng4, Kcnq2 and EphA5.

The myosin II signaling allows T cells to make selective contacts with the adhesive substrates, enabling rapid movement (Jacobelli et al., 2010).

Following this comment, we examined the dependency of ROCK / myosin II in the LPA - mediated T cell motility in a collagen matrix and found that LPA - induced T cell motility was abrogated by the treatment of T - cells with blebbistatin or the Rho kinase inhibitor Y27632.

Skeletal muscle has different types of muscle fibres with distinct variants of ATP - dependent motor proteins or Myosins.

Sarcomeres perform the muscle's contraction with the help of the contractile proteins myosin and actin, which cause the sarcomere to shorten.

No adequate explanation of this phenomenon has yet been given; but the low basal metabolic rate of whale muscle (Benedict, 1958), in combination with the high content of oxymyoglobin in vivo (cf 4.3.1), may permit aerobic metabolism to continue slowly for some time after the death of the animal, whereby ATP levels can be maintained sufficiently to delay the union of actin and myosin in rigor mortis.

You can screen for an autoimmune reaction in the heart with a blood serum antibody panel that checks for antibodies to myocardial peptide or alpha - myosin.