Sentences with phrase «with nanomolar»

For stable, yet reversible protein immobilization we have developed tris (nitrilotriacetic acid)(tris - NTA), which binds oligohististidine - tagged proteins with nanomolar affinity due to multivalent interactions (1, 2).

They identified 24 molecules with nanomolar potency against both parasites, 30 molecules causing delayed death (in toxoplasma), out of which three interfere with apicoplast segregation, an essential process for the formation of new daughter cells.

Not exact matches

Statins are HMGR inhibitors with inhibition constant values in the nanomolar range that effectively lower serum cholesterol levels and are widely prescribed in the treatment of hypercholesterolemia.

After affinity maturation, two of the designed proteins, HB36 and HB80, bind H1 and H5 HAs with low nanomolar affinity.

Chemotype Evolution has identified nanomolar inhibitors of kinases and protein - protein interactions starting from molecules with micromolar to millimolar potency.