Sentences with phrase «with nilotinib»
Moussa and other Georgetown researchers are planning larger clinical trials with nilotinib for patients with Parkinson's and other similar diseases including Alzheimer's disease, likely to begin this year.
https://gumc.georgetown.edu/
CML patients treated with nilotinib had fewer treatment - emergent BCR - ABL mutations than those treated with imatinib, and among patients who did have a mutation, those treated with nilotinib had reduced rates of progression to accelerated phase and blast phase of the disease.
GUMC says its researchers are now planning larger clinical trials with nilotinib for patients with Parkinson's and other similar diseases including Alzheimer's disease, likely to begin in 2016.
Not exact matches
Pagan said that a larger, more comprehensive study must be done before determining the drug's true impact, but if the drug's effectiveness is confirmed in such tests, nilotinib could become the first treatment to impede the killing of brain cells that's consistent with Parkinson's, according to NPR.
«Although TKIs such as the first - generation TKI imatinib mesylate (IM) and the second - generation TKIs dasatinib and nilotinib have markedly improved the prognosis of patients with chronic phase CML, a cure remains elusive.
One such agent nilotinib (Tasigna ® by Novartis), used to treat leukemia, is being studied in patients with Parkinson's and Alzheimer's diseases.
Also, nilotinib was not compared with a placebo or other medications used to treat Parkinson's in the study.
Researchers say that use of nilotinib, in doses much smaller than those used to treat cancer, was welltolerated with no serious side effects.
Moussa conducted the preclinical research that led to the discovery of nilotinib for the treatment of neuro - degenerative diseases, then partnered with Pagan for the clinical study.
Teva concluded that since the approval of nilotinib was based upon an exemption granted under Article 8 (3) with regard to the first orphan product (imatinib), it should not be entitled to same scope of orphan exclusivity as imatinib and thus should not be considered a hurdle towards the approval of generics referencing imatinib.