Sentences with phrase «with normal brain cells»

DIPGs are known as one of the most challenging tumors to treat because cancer cells are intimately intermingled with normal brain cells in a part of the brain that can not be surgically resected.

Not exact matches

The latest findings show that genetic defects in the body's ability to manufacture carnitine might be associated with an increased risk of autism because carnitine deficiency interferes with the normal processes by which neural stem cells promote and organize embryonic and fetal brain development.

«This is the first demonstration that cells carrying a genetic disease are capable of spreading into the normal mammalian brain and lead to the manifestation of behavioral abnormalities associated with the disease,» says Francesca Cicchetti, professor at the Université Laval Faculty of Medecine and researcher at Centre de recherche du CHU de Québec - Université Laval.

Work on animals has suggested that ultrasounds can in fact interfere with fetal brain development, derailing the normal movements of cells that populate the brain.

In addition, the researchers looked at brain samples of deceased patients with MS and found increased numbers of GM - CSF - producing cells in comparison to normal brain samples.

He plans to continue using optogenetics to pin down circuits of brain cells responsible for disease and to combine that knowledge with the colorful circuit images to home in on which wires need to go where to establish normal communication.

When scientists were able to prevent the excessive neurogenesis which occurs within days of the injury with a drug similar to one under trial for chemotherapy treatments, the rate of birth of new brain cells went back to normal levels and risk for seizures was reduced.

In the absence of pain, morphine interferes with normal body function and is viewed as a pathogen, activating the brain's innate immune cells and causing the release of inflammatory chemicals such as cytokines.

This turned out to be a normal protein in the cells of organisms throughout the animal kingdom — but in brains infected with scrapie and related diseases it turns up in both a normal, soluble form and an abnormal, insoluble form which accumulates in deposits that eventually kill the cells.

Normal and cancerous brain cells interfaced with graphene show different activity levels under Raman imaging.

Normal mice with p16 had fewer neural stem cells in one part of the brain and fewer new neurons in the olfactory bulb, again demonstrating p16's ability to inhibit regeneration.

Working with the brains of six normal children and seven autistic children ages 2 to 16, most of whom died of drowning, Courchesne has studied neurons under the microscope and even counted the number of neural cells in different tissue samples.

As with many other epileptic syndromes, LKS children often resume normal brain activity around age 15, when the brain cells are reaching toward maturation, perhaps spurred by hormonal change.

Working with Bhaduri, who has a background in statistics and bioinformatics, Pollen and Nowakowski began exploring how specific classes of neurons and stem cells in the developing brain contribute to normal brain growth as well as to neurodevelopmental disease, and have begun to build a comprehensive, open - source atlas of gene expression across the developing brain, which they hope will serve as a resource for other scientists.

The new study combined two methods: So - called «patch recording» of tiny voltages in single frog brain cells and how the voltages change in response to sounds of different lengths, and the administration of drugs that block neurotransmitters — a way to learn how brain cells respond to sound with and without the normal neurotransmitters.

To see what was happening in the brains of these ankyrin - G mutant mice, the researchers analyzed the cell components in inhibitory synapses connecting with pyramidal neurons, finding that two proteins known as GAT1 and GAD67 — responsible for making the neurochemical GABA that dials back nerve impulses — were at much lower levels in the synapses on pyramidal neurons in ankyrin - G mutant mice than in normal mice.

«More importantly, a retrovirus can infect only dividing cells such as reactive glial cells, but it does not affect neurons, which makes it ideal for therapeutic use with minimal side effect on normal brain functions.»

They observed a significant decrease in the number of proliferating stem cells in the brains of HIV / gp120 - mice compared with similar tissue from normal, wild - type mice.

In the mutant ferret, neural progenitor cells form abnormal clumps (in box) and differentiate earlier in the developing brain compared with the normal ferret.

The key to more effective treatment for glioma is to get to grips with the glioma stem cells, which share many characteristics with the normal neural stem cells in the brain.

In their experiments the researchers measured acidity in the endosomes of brain cells of normal mice and in mice with mutations in the NHE6 gene.

Moreover, when analyzed with gene expression patterns of normal brain cells, the four GBM subtypes associate with different cell lineages.

This program has provided the first comprehensive picture of how a gene normally associated with cancer can influence development, survival and normal function of brain cells central to age - associated neurodegenerative disorders such as Parkinson's disease.

Thank the anthocyanins (antioxidants that lend berries their hues); these substances may work with other compounds in the fruit to block enzymes that short - circuit normal communication between brain cells.