Sentences with phrase «with nucleic acids»

The new methods allowed them to catch proteins in the act of binding to RNA, and also identify what part of the protein was in contact with the nucleic acid.

Together with his principal investigator (PI), he had realized the commercial potential of modifying nanoparticles with nucleic acids to create targeted, personalized medicines for a myriad of diseases.

The exterior of the nanoparticle is coated with nucleic acids that act as targeting agents, drawing the delivery system to the retina and facilitating uptake by RPE cells.

«Many of the compounds or drugs on the market are those that interfere with nucleic acids,» Dimmock said.

A team led by Beatrice Hahn, professor of medicine at the University of Alabama in Birmingham, has now detected antibodies against the HIV - 1 precursor — along with nucleic acids from the virus itself — in the scat of wild chimps.

Scientists are also breaking ground with nucleic acid platforms that have the potential to deliver cancer vaccines, for neoantigens and other targets.

Mirkin is director of the research group that invented the chemistry for conjugating DNA and nanoparticles and a pioneer of the concept of programmable colloidal crystallization with nucleic acids.

That vision tells us we can do an awful lot with nucleic acids, be it RNA or DNA.

An autoimmune disease in which autoantibodies specific for DNA, RNA or proteins associated with nucleic acids form immune complexes.

The co-delivery of small molecular drugs with nucleic acids can improve gene transfection efficiency, reduce side - effects of these drugs, and achieve the synergistic effect of drug and gene therapy for the more effective treatment of cancer.

* Experience with nucleic acid isolation / amplification of virus isolates from tissues and infected cell culture.

And with nucleic acids, he investigated the effects of pH and especially temperature on the native properties of DNA, initiating the technique of thermal melting analysis of nucleic acid molecules and thereby contributing to an understanding of their thermodynamics and the conformational differences between duplex DNA and single - stranded RNA (5, 6).