There's little experience
with oseltamivir against H5N1, however.
Not exact matches
Jefferson, a physician based in Rome and prominent member of the Cochrane Collaboration, was charged
with reviewing studies of the antiflu drug
oseltamivir, sold as Tamiflu, during the height of the avian flu scare in 2005.
They describe virus strains
with mutations known to confer high resistance to
oseltamivir, which they isolated from a 13 - year old girl and a 35 - year old woman killed by H5N1.
In October, researchers reported the first known case of partial
oseltamivir resistance in a 14 - year - old Vietnamese girl infected
with H5N1.
The transmissible viruses were sensitive to the antiviral drug
oseltamivir and reacted well
with antisera raised against H5 influenza vaccine strains.
The virus
with this mutation remains sensitive to the antiviral drugs,
oseltamivir and zanamivir, and studies show that currently available pandemic vaccines confer protection.
Animals displaying clinical signs were quarantined and aggressively treated by veterinarians
with supplemental oxygen, anti-inflammatory medications, bronchodilators (nebulized albuterol), broad - spectrum antibiotics, and antivirals (
oseltamivir and / or ribavirin).
Unnecessary use of anti-viral medications leads to resistance within the influenza virus population so it is important that medications such as
oseltamivir not be used for infections which are not life - threatening in nature or which are likely to resolve
with routine supportive care.