The most common cancer types were breast (8), lung (3) and prostate (3),
with other cancer types including endometrial, lymphoma, ovarian, rectal and renal cancer.
The researchers» study also found that, compared with patients
with other cancer types, patients with breast cancer were 3.7 times less likely to develop PTSD at six months, but not at four years.
Not exact matches
In the most recent of these reports (in the latest issue of Science), Dr. Jennifer Wargo, a surgeon and research scientist at M.D. Anderson, along
with several dozen colleagues at
other institutions, reveal that the composition of a patient's gut microbiota can significantly influence whether he or she responds to an immune checkpoint inhibitor — the
type of
cancer immunotherapy that releases the emergency brakes in the car analogy above.
There's still much more work to do
with other types of
cancer, but the overall trajectory is pointing in the right direction.
Effective PARP inhibitors are particularly sought after by drugmakers because of their potential to be used in combination
with other types of
cancer treatments to create new breakthroughs in treatments.
The two companies plan to develop drugs to fight multiple
cancer types, either alone or in combination
with their
other cancer treatments.
It is also used
with surgery and
other medicines for managing certain
types of thyroid
cancer.
The village has seen elevated levels of unusual
types of
cancers and
other medical conditions consistent
with unhealthy PFOA levels.
The vaccination protects against infection from the two
types of Human Papilloma Virus that cause seven in 10 cases of cervical
cancer, as well as two
other types of the virus linked
with genital warts.
In the Cell study, Dr. Massagué,
with Fellow Manuel Valiente, PhD, and
other team members, found that in mouse models of breast and lung
cancer — two tumor
types that often spread to the brain — many
cancer cells that enter the brain are killed by astrocytes.
They also report that inhibition of the FA pathway coupled
with chemotherapy maybe be useful for treating
other types of
cancer.
Fior and colleagues plan to do that
with a larger group of colorectal
cancer patients and
with patients who have
other types of
cancer, such as breast
cancer.
Other researchers have already loaded hollow origami structures
with drugs to target specific
types of
cancer cells, created DNA «robots» that walk across surfaces, and mimicked the shape of viruses.
Even more than
other types of
cancer, melanoma is a disease of aging,
with older patients more frequently diagnosed
with the disease and having a worse prognosis.
«Our findings suggest that this new drug combination would also help patients
with this
type of aggressive breast
cancer as well as
other cancers, such as lung, prostate and ovarian
cancers,» Dr. Rassool says.
«The challenge is finding targets that exist on
other types of
cancer cells but not on normal cells,» says pediatric oncologist Stephan Grupp of the Children's Hospital of Philadelphia, who worked
with Porter on testing the treatment in mice.
He also plans a multicenter / multinational study of patients
with melanoma or
other types of
cancer, to examine the effect of long - term CPAP therapy on those also diagnosed
with sleep apnea.
«Pelvic RT after chemotherapy may be more beneficial in treating this form of ovarian
cancer compared
with other types,» Dr. Small said.
«Not only could the test have a major impact on treatment of prostate
cancer, but it could also be adapted to open up the possibility of precision medicine to patients
with other types of
cancer as well.»
T - rays offer hope for improved detection of
cancer, including skin
cancers like melanoma, because they track molecular signatures of malignancy that are not easily seen
with other types of scans.
«We've had luck
with other types of
cancer in removing the brakes on the immune system to allow it to fight the tumors, but this has not been the case
with glioblastoma,» said study author Anhua Wu, MD, PhD, of the First Hospital of China Medical University in Shenyang, China.
Purushotham points out, «The feasibility of intraoperative CLI as shown in this study, in combination
with the wide applicability of F -18-FDG across a range of solid
cancers, provides a stepping stone for clinical evaluation of this technology in
other solid
cancer types that also experience incomplete tumor resection due to close or involved margins.»
Cancer stem cells are strongly associated
with the growth and recurrence of all
cancers and are especially difficult to eradicate
with normal treatment, which also leads to tumours developing resistance to
other types of therapy.
This
type of integrated care model is more common in
other medical disciplines, Woolf - King said, citing pediatric oncology as an example in which recommendations have been established as part of standard care to assess mental health routinely and over time for parents of children
with cancer.
When scientists reported 2 years ago that mice
with certain gut bacteria responded best to a powerful new
type of
cancer drug,
other researchers were intrigued but cautious — mice, after all, aren't humans.
The research team
with international collaborators analysed more than 100 patient samples from ovarian and
other cancer types to discover a distinct population of cells found in some tumours.
Along
with the drug
types mentioned above,
other categories that blocked viral entry included estrogen receptor modulators used against
cancer and serotonin reuptake inhibitors used to treat depression.
More than half of patients had at least one
type of HPV DNA detectable in their oral rinses, including HPV16, the viral
type most commonly associated
with oral and
other cancers.
A nanoparticle drug - delivery system that combines two complementary
types of anticancer treatment could improve outcomes for patients
with pancreatic
cancer and
other highly treatment - resistant tumors while decreasing toxicity.
The team also found that there were also cases of
other cancer types in families
with these hereditary mutations such as leukemias and brain tumours.
Ovaries contain high levels of stress hormones compared
with other organs, but Sood plans to investigate whether the stressors could still be involved in
other types of
cancer.
Although breast
cancer was the initial focus and featured in the study published online today, the team has also conducted experiments
with other types of solid tumors,
with similar results.
«Since patients
with many
types of
cancer have elevated levels of myeloisd cells in their blood, it's possible that
other tumors could have a similar interaction
with bone to increase myeloid cell production.»
Similar
types of reminders have been done
with other preventive services such as colon and breast
cancer screenings and flu shots.
She also believes the drug could potentially be used for patients
with other types of
cancer that degrade bones, or for non-
cancer-related osteoporosis.
Researchers investigating pediatric low - grade gliomas (PLGG), the most common
type of brain tumor in children, have discovered key biological differences in how mutated genes combine
with other genes to drive this childhood
cancer.
For this purpose, the researchers used the computational tool IMPACT, developed in the Tan lab, to sort functional from missense mutations and to cross-reference candidate mutations
with those previously reported in
other cancer types.
Patients
with other types of
cancer have reported similar problems.
Obesity is associated
with and contributes to a shortened life span,
type 2 diabetes, cardiovascular disease, some
cancers, kidney disease, sleep apnea, osteoarthritis and
other conditions.
However, lingering infections
with a subset of about 19 «high - risk» HPV
types can lead to the development of cervical
cancer or
other genital / anal
cancers.
Additionally, the prognosis for patients
with TNBC is usually poorer than for those
with other types of breast
cancers.
The research team is also developing and testing the system for use by people
with other types of
cancer and long - term conditions such as heart failure.
To explore this idea, Hopkins oncologists Dung Le, Luis Diaz, and
others looked for mismatch repair mutations in tumor samples from patients
with advanced colon
cancer and
other cancer types whose tumors had stopped responding to
other treatments.
Of 10 patients
with other types of
cancer — including pancreatic, prostate, and uterine — who had mismatch repair mutations, in seven their tumors shrank or remained stable; the
other three progressed.
The results show that generation of an optimal immune response to
cancer requires cooperation between two
types of memory T cell — one circulating in the blood and the
other resident in tissues — that can be reactivated
with current immunotherapy strategies.
Tumor profiling can also reveal rare mutations and
other changes that make some
cancers unusually responsive to targeted drugs — knowledge that can be applied to patients
with a variety of
cancer types.
«What we think this might mean is that these de novo, new, genetic changes may be more relevant to early onset
cancers with an impact on fertility,» says Stadler, since testicular
cancers more often occur during reproductively active years than the
other cancer types.
«We're recommending that we do an additional trial to confirm these results and see how it would extend to
other populations,» says Clark, in particular women and those
with certain
cancer types.
PD -1-blocking agents such as nivolumab, pembrolizumab and atezolizumab are part of a class of drugs known as checkpoint inhibitors, and many
cancer researchers are now trying to figure out how to enhance their activity by combining them
with other types of drugs.
Jacks» lab is now investigating the roles of genes associated
with other types of lung
cancer, such as small cell lung
cancer.