Sentences with phrase «with other cell types»

Compared with alternative protocols for biliary differentiation of hPSCs, our system does not require coculture with other cell types and relies on chemically defined conditions up to and including the generation of CPs.

I predict we will find that there are programs that link all these cells together, that when a cell is under stress it is communicating with these other cell types, leading to degeneration.

One of these tissue types, specifically the mesoderm, develops into skeletal muscle cells (along with other cell types, including cardiac muscle, kidney cells, red blood cells, and smooth muscle).

Not exact matches

The squeeze mechanism Sharei and his colleagues came up with could also be more effective than other existing ways of getting materials into cells, he says, because it works for more types of cells and materials, and presents fewer risks.

Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis disease or are human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear of lesions).

Choose an obstetrician or health care provider Interview potential doctors Contact health insurance company about coverage Start and pregnancy and birth budget Discuss financial effects of pregnancy and baby with partner Stop smoking Stop drinking Stop using street drugs Talk to your physician about any prescription medications Drink at least 8 glasses of water every day Visit the doctor at least once per month or every 4 weeks Do not dye or perm hair Stop drinking coffee and other caffeinated beverages Exercise daily Start taking prenatal vitamins Eat foods rich in folic acid Eat iron rich foods Increase daily intake of whole grains, fruits and vegetables Nap as much as possible as fatigue is common Eat fish with low levels of mercury no more than 2 days per week Do not eat undercooked meats Do not eat unpasteurized dairy producs Do not eat cold cut deli meats Allow someone else to clean out the kitty litter, if applicable Limit exposure to chemicals Try to limit stress and tension Complete all prenatal tests — HIV, Chlamydia, Gonorrhea, Anemia, Blood Typing, Sickle Cell Anemia, Urine Screening and Rubella.

«We compared F. hygrometrica data with those from land plants and seaweeds,» explains Itouga, «and found that the presence of polygalacturonic acid in the cell wall is one of the characteristics that separated this type of moss from other plants.»

It is these people who develop diabetes, either type 1 or type 2, while others with tougher beta cells will remain healthy even in if they suffer from autoimmunity or metabolic dysfunction of the liver.»

When combined with other polymers, the structures could also convert light into electricity and serve as the basis for a novel type of solar cell.

In the Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocytes.

Also, researchers could carefully select which blood types to culture with each batch of stem cells, creating stockpiles of needed blood products for people with extremely rare blood types whose blood cell makeup makes it challenging to find good blood matches for transfusions because they would reject most other types of blood.

Other researchers have already loaded hollow origami structures with drugs to target specific types of cancer cells, created DNA «robots» that walk across surfaces, and mimicked the shape of viruses.

When mixed with two other types of cells, the fabricated primitive liver cells organized themselves into three - dimensional structures, complete with blood vessels.

«The challenge is finding targets that exist on other types of cancer cells but not on normal cells,» says pediatric oncologist Stephan Grupp of the Children's Hospital of Philadelphia, who worked with Porter on testing the treatment in mice.

Now, with new kinds of technologies that are coming up, new types of tissue engineering and, you know, some of the hopes that people have for stem cells and [the] like, it may be interesting to see if there are other ways, alternatives to dealing with really badly damaged hearts that would involve growing a new heart or replacing or repairing the damage d to a badly damaged heart that might make artificial hearts less important in the somewhat more distant future.

«We could get some shrinkage of the tumours with other types of treatment we tried before, but we never got a complete cell kill,» he says.

Professor Dan Davis and his team at the Manchester Collaborative Centre for Inflammation Research, working in collaboration with global healthcare company GSK, investigated how different types of immune cells communicate with each other — and how they kill cancerous or infected cells.

Other brain researchers had identified certain cell types and areas of the brain associated with fear, reward, addiction, and depression.

These resultant haploid cells can fuse with other haploid cells of the opposite sex or mating type during fertilization to create a new diploid cell, or zygote.

The researchers found five different sub-types of HL among the patients studied: 247 cases of the nodular sclerosis (NS) type, in which the tumour nodules are large; 105 of mixed cellularity, where a mixture of different types of inflammatory cells are involved; 58 lymphocyte rich, the sub-type with the best outcome; 68 «others»; and 143 «not otherwise specified» (NOS).

Previous studies showed that cells which express the same type of cadherin interact with each other, but cells with different types of cadherins remain separate.

Meanwhile, biologists elsewhere were whipping up other types of organoids, starting instead with adult stem cells.

Cancer stem cells are strongly associated with the growth and recurrence of all cancers and are especially difficult to eradicate with normal treatment, which also leads to tumours developing resistance to other types of therapy.

Others have suggested that the apparent transdifferentiation might result from immature cells fusing with mature cell types from other tissues.

With this discovery, DYRK1A, known from past studies to drive cell division in other cell types, becomes a drug development target.

«Because of the Harvard Stem Cell Institute, we were able to work with other researchers to make patient cells into any type of neuron,» said Young - Pearse, whose lab spent two years fine - tuning protocols with collaborators to generate the neurons needed for her early onset Alzheimer's study.

«If we want to treat patients with liver disease, we only want to silence targets in the liver, not other cell types.»

The research team with international collaborators analysed more than 100 patient samples from ovarian and other cancer types to discover a distinct population of cells found in some tumours.

Warnke's technique circumvents these limitations and could be adapted to work with other types of cells.

In neurons of DIXDC1 mutant mice (center) the dendrites — neural antennae that receive input from other brain cells — have fewer of the dendritic spines (white with red arrows)-- the receiving half of most synaptic inputs — compared to dendrites in wild type mice (left).

These cells were not affected in patients with SLE, dermatomyositis, or other type I interferonopathies, however, suggesting that the source of interferon - can vary depending on the autoimmune disease.

In the fruitfly testis niche, previous studies have shown that different stem cell types had to coordinate with each other.

«Simply by counting cell types, we immediately saw that there were more Tregs in the older mice with diabetes than any other group.»

Once lymphocytes find such invaders within the lymph node, they destroy them in collaboration with other types of immune cells.

In patients with severe asthma, however, NK cells are disabled from resolving inflammation, and become outnumbered by other types of immune cells that provoke inflammation.

In his look at the wider benefits of vaccines, Michael Brooks describes type 1 and type 2 helper T - cells as competitive, with levels of one going down as the other goes up (17 August, p 38).

«Since patients with many types of cancer have elevated levels of myeloisd cells in their blood, it's possible that other tumors could have a similar interaction with bone to increase myeloid cell production.»

By comparing hippocampal and cortical neurons in mono - culture (with other cells of the same type) and in co-culture (both cell types deposited within one device), the research showed that some features from hippocampal cells, like the percentage of action potential spikes found in bursts, were significantly higher when cultured together with cortical cells.

By repeating the experiment over and over, however, they are assembling a picture of what types of cells exist, how those cells function during tasks of place memory, and what kinds of connections they form with other cells.

Now a team at the Wyss Institute of Biologically Inspired Engineering at Harvard University and Harvard Medical School, in collaboration with the Allen Institute for Brain Science, has developed a new method that allows scientists to pinpoint thousands of mRNAs and other types of RNAs at once in intact cells — all while determining the sequence of letters, or bases, that identify them and reveal what they do.

«We're interested in learning more about what other proteins LRP6 interacts with, as well as how it acts in different types of brain cells at different developmental stages of circuit development and refinement.»

The researchers analysed cells from healthy individuals and others with type 2 diabetes and found 25 820 regions of the genome with altered DNA methylation.

WHEN DISCUSSING neurotransmitters, most people think of the classical neurotransmitters, such as dopamine and serotonin — the primary chemical messengers used by neurons to communicate with one another and with other types of cells.

Bacteria share DNA with other organisms with which they come into contact, so an antibiotic - resistant gene can transfer from one type of bacterium to another, and a bacterial cell can become resistant to numerous antibiotics at once.

Due to the build - up of toxic glycogen clumps in neurons and other cell types, patients with this disease commonly experience severe epileptic seizures, motor impairment, muscle spasms, and dementia.

One potential treatment involves injecting the wound with stem cells, which can change into other cell types, such as skin cells like keratinocytes, to help with the healing process.

Early in postnatal development, before this bouquet of cells makes connections with other types of neurons, the cells engage in cross-talk among themselves, Michael Hausser has found.

Future treatment of OS patients with this type of antibody could reduce amputations among young patients and future studies will clarify if such a treatment strategy will also block lethal spreading of the OS cells to other organs.

They tried hundreds of different recipes; eventually they discovered that if they mixed liver precursor cells (derived from iPS cells) with two other types of standard human cell lines known to be important for embryonic liver development, then the cells would spontaneously form a 4 to 5 - millimeter 3D structure called a liver bud.

He agreed with Shankar that the RNAi method would not lead to a stand - alone treatment «The virus goes beyond T cells,» he says, noting that it attacks several other types of immune cells.