39, 40 Previous studies have been performed
with other chemotherapy agents such as: carboplatin, gemcitabine, doxorubicin, paclitaxel, 5 - fluoracil, camptothecin, bevacizumab and docetaxel10.
«This promising treatment strategy may also help us reduce toxicity when used
with other chemotherapy agents.»
Not exact matches
They also report that inhibition of the FA pathway coupled
with chemotherapy maybe be useful for treating
other types of cancer.
The same rings true when immunotherapy is paired
with other cancer treatments like
chemotherapy, for example.
Though many people can survive leukemia
with chemotherapy and
other drugs, Porter's patients had not responded to any of the available treatments.
Many clinical trials combine virotherapy
with chemotherapy or
other immunosuppressive agents to try to allow the virus to survive and infect as many cancer cells as possible.
A transplant of hematopoietic stem cells attempts to cure patients
with certain cancers and
other serious illnesses that have not responded to conventional
chemotherapies.
The study evaluated 56 patients
with ovarian clear cell adenocarcinoma (CCA), an aggressive form of ovarian cancer that is more likely to be resistant to
chemotherapy and to have a poorer prognosis than
other forms of this disease.
«Pelvic RT after
chemotherapy may be more beneficial in treating this form of ovarian cancer compared
with other types,» Dr. Small said.
«If, as we postulate, the combination of
chemotherapy and PARP inhibition is successful in treating patients
with HRD tumors, I expect that
others will start exploring whether similar drugs or analogous therapies can make a difference in these diseases,» Heeke concludes.
For example, women whose cancer was no longer controlled by letrozole or
other aromatase inhibitors, those who had already begun to receive
chemotherapy, and premenopausal patients
with metastatic disease.
«Reactions between
chemotherapy drugs and
other substances that the drugs come in contact
with have, as far as we know, never been studied like this before,» Wells says.
«This research has produced valuable information about the interaction between
chemotherapy drugs and
other substances that the medicine is in contact
with.
«ALK now becomes the second abnormal gene that we are able to successfully target in lung cancer
with drugs
other than
chemotherapy.»
The same approach may be useful for boosting the effects of
chemotherapy in
other types of solid tumour
with high levels of stroma, Ganss says.
In
other words, patients
with a methylation pattern resembling that of healthy people's HSCs (i.e., a «low score») would be more likely to live longer — and therefore benefit more from
chemotherapy — than patients
with a high score.
By the 1940s — when researchers discovered that a chemical warfare agent, nitrogen mustard, suppressed cancer —
chemotherapy with nitrogen mustard and
other agents, along
with radiation therapy and surgery, began to supplant Coley's toxins.
Therefore, «this finding may represent a future therapeutic strategic to combine
with other strategies, such as immunotherapy,
chemotherapy or inhibitors against specific signalling routes of the tumour cells.»
Tamara Minko, professor in the Ernest Mario School of Pharmacy, and Lorna Rodriguez, professor of obstetrics, gynecology and reproductive sciences at Robert Wood Johnson Medical School, say because there is not a good screening method for ovarian cancer, most women
with the disease are not diagnosed until after it has metastasized to
other organs and surgery and
chemotherapy are not as effective.
The median number of prior therapies for these patients was three; all the patients had been treated previously
with at least one
other EGFR TKI therapy, and most patients receiving
chemotherapy as well.
Current antifungals also have a narrow spectrum of activity, and some interact
with other drugs such as
chemotherapy agents and immunosuppressants.»
This can be useful to recommend that these tumors do not be conformed to surgery and determine that it will probably be necessary to administer adjuvant
chemotherapy in
other words, in those tumors
with a more «benign» epigenetic pattern; surgery alone may be curative, thus avoiding the side effects of
chemotherapy, «concludes the researcher.
Some raised it early in their consultations
with patients,
others late in the process, leading some patients to feel their doctors had already made the decision to recommend
chemotherapy.
The study, led by Deborah Armstrong at the Johns Hopkins Kimmel Cancer Center in Baltimore, Maryland, builds upon evidence from eight
other clinical trials showing an overall survival benefit of approximately one year for women treated
with IP
chemotherapy after «optimal debulking» — surgery to remove most, if not all, of the cancer in the abdomen.
Surgery, radiation and
chemotherapy do prolong survival by several months, but targeted therapies, which have been effective
with other forms of cancer, have not lengthened survival in patients fighting glioblastoma.
Combination therapies often include multiple types of
chemotherapy or
chemotherapy combined
with other treatment options.
Combination
with other IO agents, targeted therapies, and
chemotherapies are the top common strategies.
The bright, airy building is stocked
with the latest devices for imaging and radiation therapy and includes private
chemotherapy rooms, on - site labs, a nutrition center and patient library, among
other resources.
Since stem cells are also critical for regeneration in the intestine, therapies that target these pathways may further help to design new drugs that reduce side effects associated
with chemotherapy, radiotherapy or
other causes of intestinal damage.
Researchers are eager to develop more such drugs and see if they can boost their effectiveness by using them in combination
with other treatments, such as
chemotherapy and radiation.
Combination therapies often mix multiple types of
chemotherapy or combine
chemotherapy with other treatments.
This indicated that HOXA9 methylation levels, as detected via ddPCR technology, could be used in combination
with other biomarkers to identify high - risk stage IA and IB patients and potentially steer these patients for follow - up
chemotherapy to prevent recurrence.
Radiation is often used in conjunction
with other cancer treatments such as surgery,
chemotherapy or bone marrow transplant, depending on each child's specific diagnosis.
Stem Cells Make Bone Marrow Cancer Resistant to Treatment Scientists at the Johns Hopkins Kimmel Cancer Center provided evidence that cancer stem cells for multiple myeloma share many properties
with normal stem cells and have multiple ways of resisting
chemotherapy and
other treatments.
Researchers note that while PCI - aided delivery of
chemotherapy to the brain has proven effective in laboratory tests, additional testing prior to human clinical trials is needed to identify
other less - toxic blood - brain barrier agents to be used in tandem
with the photosensitizer in the PCI process.
By learning as much as possible about those unique changes, and developing specific drugs and therapies to target them, we at City of Hope believe many cancers can be defeated at the molecular level, often
with fewer side effects compared to traditional
chemotherapy and
other treatments.
Although some cancers can be fatal,
others can be successfully treated
with procedures like surgery and
chemotherapy.
In the US, the National Institutes of Health states that there is clear - cut evidence that acupuncture is useful in treating post-operative pain,
other chronic pain disorders, and the nausea and vomiting associated
with pregnancy or
chemotherapy.
Nutritional ketosis has received a lot of attention by cancer researchers in recent years, and many studies show it has great potential not just as a form of cancer prevention but also treatment — in combination
with other treatments such as
chemotherapy and radiation.16 Research is looking at whether non-toxic metabolic therapies and drug cocktails may be just as effective,
with less toxicity.
Peripheral Neuropathy: Pathogenic Mechanisms and Alternative Therapies Alternative Medicine Review 2006 (Dec); 11 (4): 294 - 329 ~ FULL TEXT Peripheral neuropathy (PN), associated
with diabetes, neurotoxic
chemotherapy, human immunodeficiency virus (HIV) / antiretroviral drugs, alcoholism, nutrient deficiencies, heavy metal toxicity, and
other etiologies, results in significant morbidity.
Peripheral Neuropathy: Pathogenic Mechanisms and Alternative Therapies Alternative Medicine Review 2006 (Dec); 11 (4): 294 — 329 ~ FULL TEXT Peripheral neuropathy (PN), associated
with diabetes, neurotoxic
chemotherapy, human immunodeficiency virus (HIV) / antiretroviral drugs, alcoholism, nutrient deficiencies, heavy metal toxicity, and
other etiologies, results in significant morbidity.
• Reduces colon spasms and gas • Relieves upset stomachs and indigestion • Enhances gastric emptying • Improves colic in babies • Prevents cracked and sore nipples in breastfeeding mothers • Relieves hay fever and
other allergies • Treats tuberculosis • Reduces pain associated
with shingles • Reduces nausea associated
with chemotherapy • Inhibits Prostate cancer • Protects against DNA damage from radiation • Inhibits the herpes simplex virus type 1 • Improves oral health and bad breath • Relieves respiratory disorders • Relieves headaches and muscle pain • Reduces stress • Treats lice and dandruff
There are more than four hundred colors and the company donates money from sales to charities helping cancer patients
with costs during
chemotherapy, and
other charities «dedicated to healing».
Cancer that has spread to
other organs or lymph nodes can be surgically removed and then followed
with chemotherapy.
Diseases of particular interest to Dr. Culp include malignant obstructions (cancer resulting in blockage of the urethra, ureter, trachea, esophagus, and colon), non-resectable tumors (tumors that can not be removed
with traditional surgical techniques), tumors that can be treated
with direct delivery of
chemotherapy to their blood vessels, vascular abnormalities (portosystemic shunts, arteriovenous malformations) and
other conditions causing blockage of the ureter.
Treatment
with a single
chemotherapy drug, most commonly doxorubicin (Adriamycin ®), although
others can be used.
We work closely
with a local Veterinary Internal Medicine Specialist who can provide ultrasounds, echocardiograms,
chemotherapy, endoscopy and biopsy, as well as
other consultations as needed.
With other types of cancers (many sarcomas, carcinomas, etc.) surgery is the first line of therapy and
chemotherapy may be used if after surgery the disease is still present microscopically at the surgical site or the cancer is determined to be at high risk for spread (e.g. osteosarcoma).
On the
other hand, people
with immune system problems, such as those
with HIV / AIDS, those taking certain types of
chemotherapy, or persons who have recently received an organ transplant, and infants, may develop severe toxoplasmosis, which results in damage to the eye or the brain.
The next research step is to further investigate propranolol and
other beta blockers to see if they will work in combination
with chemotherapy drugs, and then move to testing this new treatment approach in dogs
with hemangiosarcoma.