Not exact matches
Our brains also regulate thousands of complex
functions, usually without bothering the conscious us
with the exact details, such as
with circadian rhythm,...
Altering the
function of the clock
circadian regulator (CLOCK) and brain and muscle ARNT - like protein 1 (BMAL1), which keep cellular
functions synchronized
with day - night
rhythms, could treat metabolic problems.
«The «misalignment» or mismatch between early school start times and teens»
circadian rhythms — which normally shift later
with puberty — may worsen self - regulation or so - called «executive
functioning,»» says Owens.
PER2: Deletion of the PER2 gene in mice, associated
with the mechanisms of
circadian rhythm, appears to improve DNA repair in stem cell populations relevant to the immune system, resulting in a healhier immune cell population, better immune
function in old age, and a modestly extended life span.
These include altered and / or decreased immune system
function (possibly linked to infections and allergies), collagen loss (think wrinkles), decreased muscle synthesis, increased abdominal fat, bone breakdown, decreased intestinal immunity (possibly leading to GI infections), damage to the lining of the intestines (or leaky gut syndrome), increased stomach acid secretion (think heartburn and ulcers), hippoacampus destruction (leading to problems
with circadian rhythm, memory, and causing a feed - forward vicious stress cycle), increased blood pressure, thyroid hormone imbalances, «shutdown» of the reproductive system (possibly leading to miscarriage or infertility), and more.
The authors of the review suggested that cirrhosis can affect
function in the area of the brain that regulates our
circadian rhythm and this explains the sleep disruption associated
with liver disease.
«By directly interacting
with melatonin receptors in the brain and peripheral tissues, environmental chemicals, such as carbaryl, may disrupt key physiological processes leading to misaligned
circadian rhythms, sleep patterns, and altered metabolic
functions increasing the risk for chronic diseases such as diabetes and metabolic disorders,» said Dubocovich.