The discovery of small molecule regulators (activators or inhibitors) of epigenetic modification enzymes provides researchers
with pharmacological tools with which to investigate the biological consequences of chromatin modifications.
Not exact matches
Using electrophysiology and
pharmacological tools, the research has shown that a potassium channel, specifically the BK channel, in the central nervous system can be regulated
with drugs to increase or decrease these disruptions in animal models.
The novel licensing agreement is focused on the discovery of
pharmacological molecules offering a therapeutic solution and it is designed to streamline access to intellectual property associated
with the SMN gene and thus speed the development of assays, models and other
tools that are critical to the discovery process.