Sentences with phrase «with rosiglitazone»

«Our post-trial analysis compared patients treated with rosiglitazone to patients not receiving any TZD drug.

Not exact matches

Importantly, while using rosiglitazone in conjunction with targeted therapy reduced tumor growth in both young and aged pre-clinical models, using rosiglitazone alone accelerated tumor growth in young models, while inhibiting it in aged ones.

The researchers showed that a two - day treatment regimen with partial or selective PPAR - γ agonists (Telmisartan and Rosiglitazone — both FDA - approved drugs) ameliorated the pathological outcomes of infection in mice by inducing expression of glucose transporters.

However, it is commonly associated with diabetes, which has prompted researchers to test diabetes medications, such as metformin, rosiglitazone and liraglutide, as potential treatments.

When BubR1H / H; INK - ATTAC mouse bone marrow cells were pushed into senescence in vitro by the PPAR - γ - activating drug rosiglitazone, a subpopulation of the cells exhibited high levels of INK - ATTAC expression and GFP, coupled with SAβ - gal staining; subsequent to treatment with the INK - ATTAC activating drug, these cells rapidly entered into apoptosis, and within 48 h were either destroyed or in the cell death process.

Taking either rosiglitazone or Lovaza with metformin seemed to mitigate some of the negative heart effects of metformin alone in men.

But women, already benefiting from metformin, improved heart metabolism further by adding rosiglitazone, with the desired effect of reducing the heart's dependence on fat metabolism.

The diabetes drug rosiglitazone has been under intense scrutiny since a 2007 study in the New England Journal of Medicine looked at more than 40 clinical trials and linked the drug's use with increased risk of heart attack and death from heart disease.

Peri-ovulatory Rosiglitazone treatment reverses impaired embryo development associated with obesity.

Metformin is also sold under the brand names Glucophage and Glucophage XR, and is found in pills that combine two types of antidiabetes medication, such as Glucovance and Metaglip (which combine metformin with a sulfonylurea drug) and Avandamet (a combination of metformin and rosiglitazone, a thiazolidinedione medication).

Furthermore, rosiglitazone increased mortality in those with type 2 diabetes [34].

Avandia (rosiglitazone) is the poster child for what is wrong with the drug treatment of type 2 diabetes.

In the report, published in the December 2007 issue of Nature Medicine, researchers from the Salk Institute in La Jolla, California report that rosiglitazone (Avandia) has been shown to interfere with >> Read Article

Rosiglitazone use was associated with a 25 % higher risk of heart attack.