Sentences with phrase «with sickle cell disease»
Phenotype and Epidemiological Profile of Children with Sickle Cell Disease Followed - Up at the Mother and Child Hospital of N'Djamena
http://www.scirp.org/
The lived experiences of adolescents with sickle cell disease in Kingston, Jamaica.
Topics include getting screened, supporting students with sickle cell disease, tips for preventing infection, and more.
Most folks with sickle cell disease will experience heavy resistance when apply for traditional life insurance.
Someone with sickle cell disease could experience a variety of complications throughout their life.
People with sickle cell disease living in the malaria belt had more grandchildren than those around them in their area at the time the trait became widespread.
New Insights on Pain and Opioid Use in People With Sickle Cell Disease After Hematopoietic Stem Cell Transplant (March 12, 2018)
Participants must be 16 years or older with sickle cell disease and have a stem cell donor.
One study made up of 37 teenagers with sickle cell disease found that higher levels of daily stress were associated with increases in same - day pain levels (7).
Hants also created the first (and only clinical validated) remote, mindfulness - based intervention for individuals with Sickle Cell Disease and chronic pain.
But the one that I am most proud of is the development (clinical trial) of the first and only remote telephonic mindfulness - based stress reduction program for individuals with Sickle Cell Disease and chronic pain.
Scientists have successfully used gene editing to repair 20 to 40 percent of stem and progenitor cells taken from the peripheral blood of patients with sickle cell disease, according to Rice University bioengineer Gang Bao.
Though the life expectancy of a person with sickle cell disease has increased dramatically over the past few decades, it is still much shorter than the average life expectancy.
One in every 500 African Americans and one in every 30,000 Hispanic Americans are born with sickle cell disease, according to the Centers for Disease Control and Prevention.
Scientists have successfully used gene editing to repair 20 to 40 percent of stem and progenitor cells taken from the peripheral blood of patients with sickle cell disease, according to Rice... Read more
Endari, the first new treatment for patients with sickle cell disease in almost 20 years, Genentech's Hemlibra, the first - ever non-blood product to treat patients with hemophilia A with inhibitors, Actemra, the first treatment for adults diagnosed with giant cell arteritis, BioMarin's Brineura, the first treatment for a form of Batten disease, Benznidazole, the first U.S. treatment for Chagas disease, Novartis» Kymriah to treat certain children and young adults with B - cell acute lymphoblastic leukemia, which is also the first gene therapy to become available in the United States, are some of the drugs that received the FDA's stamp of approval in 2017.
«Stem cells are our only hope,» Adrienne continues, «It's my true belief that I'm going to be the last woman in my family to have a child with sickle cell disease.
St. Jude researchers are now leading a multi-center trial to determine if toddlers with sickle cell disease would benefit from a similar dosing strategy or would respond better to a standard dose.
Dr. Haywood's dissertation examined the association of patient - centered care with trust in the medical profession among adults with sickle cell disease.
Attitudes toward clinical trials among patients with sickle cell disease.
From birth to adulthood, we help patients live with sickle cell disease, while we continue to research new cures and better long - term care.
«For example, despite matching the ABO blood group antigens during red blood cell (RBC) transfusion, up to 45 percent of chronically transfused patients, such as those with sickle cell disease or thalassemia, develop antibodies to mismatched minor antigens on transfused RBCs; this process is known as alloimmunization.»
A video - intervention to improve clinician attitudes toward patients with sickle cell disease: the results of a randomized experiment.
A «Narcotics Contract» for a Patient With Sickle Cell Disease and Chronic Pain.
Examining the characteristics and beliefs of hydroxyurea users and nonusers among adults with sickle cell disease.
Kenneth Ataga, MD, director of the UNC Comprehensive Sickle Cell Program, was featured in a video by the American Society of Hematology in which he discussed the favorable results of a yearlong clinical trial studying crizanlizumab as a therapy to prevent and treat painful crisis events in patients with sickle cell disease.
The study represents an important step toward more effectively treating certain patients with sickle cell disease who need frequent blood transfusions and currently have few options.
But, he says, «This study shows it may be possible in the not - too - distant future to provide patients with sickle cell disease with an exciting new treatment option.»
The drug, called SelG1, also reduced the frequency of pain crises in people with sickle cell disease and reduced the number of days they spent in the hospital.
The problem for patients with sickle cell disease is that lab - grown stem cells with their genetic material would have the sickle cell defect.
And Belle is right: Patients with sickle cell disease and other serious blood conditions rely on donors to keep their blood flowing and hearts beating.
Researchers at Johns Hopkins have successfully corrected a genetic error in stem cells from patients with sickle cell disease, and then used those cells to grow mature red blood cells, they report.
Exciting clinical applications of gene editing include correcting the mutation in the bone marrow stem cells of patients with sickle cell disease or hemophilia.
«For patients with sickle cell disease, blood donors are a matter of life and death.»
Genomic analyses of pneumococci from children with sickle cell disease expose host - specific bacterial adaptations and deficits in current interventions.
He hopes the study will increase awareness among physicians who can screen for sleep disordered breathing in adults with sickle cell disease.
Dr. Sharma theorized that the diagnosis of sleep disordered breathing could be missed in this population because adults with sickle cell disease are not generally obese, a common risk factor for apnea, and daytime sleepiness is attributed to the pain medications necessary to treat symptoms of the disease.
A new study in the Journal of Clinical Sleep Medicine revealed that 44 percent of adults with sickle cell disease who report trouble sleeping actually have a clinical diagnosis of sleep disordered breathing, including sleep apnea, which lowers their oxygen levels at night.
By forcing adult mice with sickle cell disease to produce a fetal version of the hemoglobin molecule that carries oxygen in blood, a research team has eliminated symptoms of disorder in the animals.
Recently, scientists have uncovered many of the molecules in the pathway that control the switch from fetal to adult hemoglobin, opening the door to new therapies; if you could prevent the switch from happening, or reverse it, and let people with sickle cell disease use fetal hemoglobin for life, that should reduce symptoms.
Medical support for a single patient with sickle cell disease can run $ 25,000 a year or $ 1 million over a lifetime.
The new findings and the fact that patients with sickle cell disease have significant variability in their nitric oxide levels — even during a pain crisis — likely explains why, Ikuta said.
Low levels of both oxygen and the powerful blood vessel dilator nitric oxide appear to have an unfortunate synergy for patients with sickle cell disease, researchers report.
«Patients with sickle cell disease have had few therapeutic options.
The scientists did this by manipulating a small molecule known as sphingosine -1-phosphate (S1P), which they report is found in elevated levels in people with sickle cell disease.
Nearly 100,000 people in the United States are living with sickle cell disease, a group of inherited blood disorders.
«Secondary benefits of this trial include the significant improvement in clinical care for children with sickle cell disease at each of the 29 sites because each location had a designated hematologist, neurologist, neuroradiologist and psychologist working as a team to identify and decrease further injury to the brain in this vulnerable population.»
Patients with sickle cell disease are commonly prescribed a daily, long - acting painkiller taken at a constant dose, and a short - acting painkiller to be taken as needed for episodes of more severe pain.
These experts were supported by a large staff of NHLBI leaders and other personnel, including experts in finding and analyzing the available scientific evidence that could help improve the lives of people with sickle cell disease.
Currently, there are not enough physicians who specialize in the care of adults with sickle cell disease, which means that many are seen by primary care physicians or other specialists,» said Ms. Miller.