Sentences with phrase «with significant consequences»

«Our studies provide the first evidence that people do compare their partner to others with significant consequences for the relationship,» says Thai.

It is a rookie mistake with significant consequences.

But doctors are imperfect and they can make errors with significant consequences, such as nerve damage, loss of a limb, paralysis, and even death.

While time served may not seem like a big deal, a conviction for a criminal offense is permanent and carries with it significant consequences that will follow you for the rest of your life.

These are serious charges with significant consequences.

Since then the human enterprise has experienced a remarkable explosion, the Great Acceleration, with significant consequences for Earth System functioning.

And I believe there are examples of gravity applied to a gas in uniform thermal equilibrium with significant consequences.

You have to remember that getting a credit card is a serious decision with significant consequences to your credit standing.

Early lump sum withdraws from a pension plan come with significant consequences.

The framework for our overall project also points to the mostly indirect influence of principals «actions on students and on student learning.223 Such actions are mediated, for example, by school conditions such as academic press, 224 with significant consequences for teaching and learning and for powerful features of classroom practice such as teachers «uses of instructional time.225 Evidence - informed decision making by principals, guided by this understanding of principals «work, includes having and using a broad array of evidence about many things: key features of their school «s external context; the status of school and classroom conditions mediating leaders «own leadership practices; and the status of their students «learning.

Water droplets condense around aerosols, so their presence affects the ways clouds form and behave — with significant consequences for the climate as a whole.

What we have done is to show that a specific mechanism exists by which bacteria in the gut can influence this process with significant consequences for the host,» commented Dr Gahan.

Changes in N2 fixation due to global warming will alter N input to arctic ecosystems with significant consequences for plant growth.

Thanks to the internet, rumours, inaccuracies and lies have the means to bounce around social networks, blogs and news sites with unprecedented speed — and often with significant consequences.

This shin - kicking contest, though, comes with significant consequences, especially for the city's public school students and rent - stabilized tenants.

Add to that the multiple competing interests in such a situation and the opportunity for a wrong decision with significant consequences is magnified many times over.»

Not exact matches

But the reason it was so significant to me is that it was a noble, philosophically sound approach with early success but with some unpredicted and undesirable consequences.

Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the effect of changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of changes in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.

However, even with all the freedom that youth provides, it can come with some significant financial consequences that can be crippling if you're not careful.

There are significant consequences if the provider you choose fails to detect structural problems with the property.

And I don't think any of us can pretend Christianity doesn't matter - as a social movement it's been tremendously significant with many consequences, some good some bad.

The presidents were suspicious of a juridical approach, both because they saw the mandate as jeopardizing the academic autonomy of Catholic universities and because they feared the mandate could entangle universities in unnecessary lawsuits with significant financial consequences.

It must be, rather, that their conflicts are so significant that the types of education which one receives under their influences differ radically — and with decisive social consequences.

This trend is likely to have been more accentuated since 1971 with the increase in the number of stations finding paid - time religious programs acceptable: a significant consequence of the economic motivation of the general television industry.

The former teammates come head - to - head this weekend in a clash that could have significant consequences on this season's Premier League title race, with the Blues currently leading at the top of the table by nine points.

It is unlikely that we missed any significant adverse consequences by excluding infants changing from supine to nonsupine after the 3 - month report, because only 3 % of all infants with complete data were excluded for this reason.

All this has a raft of significant consequences: a new parliament and government for England, a written constitution defining the powers of the two tiers, endowment of the Supreme Court with powers to interpret and enforce the federal constitution, transformation of the House of Lords into a federal Senate, negotiation of a framework for revenue allocation, and much more.

As significant welfare reform and housing bills make their way through parliament this legislative year, debates on cutting housing benefit for 18 - 21 year olds, and the security and affordability of the private rented sector will all come to play — with potentially dire consequences for people at the cusp of becoming homeless.

Former President John Mahama believes the New Patriotic Party (NPP) government is becoming incapable of dealing with vigilante groups affiliated to it, that continue to wreak havoc without any significant consequences.

She later added, «with no discussion of strategy and consequences, which could be significant, I do not support this decision.»

Warnings from the head of MI6 lead the committee to conclude: «There has to be a significant risk that some of the country's chemical weapons stockpile could fall into the hands of those with links to terrorism, in Syria or elsewhere in the region — if this happens, the consequences could be catastrophic.»

He doesn't want to poke this particular bear with that particular political «schtick,» because the consequences can be significant.

Numerous candidates with delinquent campaign finance disclosure reports had long been able to carry on without suffering significant consequences for failing paying fines assessed against them; Pedro Espada rose to the Senate's top position with dozens of missing reports and about $ 30,000 in unpaid fines.

«By implementing a new policy of issuing a summons rather than arresting New Yorkers for possessing small amounts of marijuana, the mayor and commissioner have taken a significant step towards ensuring fewer New Yorkers face the consequences that arrest records bring,» Mr. Torres said on November 10 in a joint statement with Councilmen Carlos Menchaca, Donovan Richards and Antonio Reynoso — all of whom came out today in support of the Right to Know Act.

The agreement finally reached on the local government pension scheme after the government made significant concessions has rather less to do with official generosity than fear about the consequences if the scheme were so eviscerated that hundreds of thousands of local government workers might decide there was no point in continuing to contribute to it since, if they walked away, they would still get the same amount of money in retirement from means - tested income support.

The National Science Advisory Board for Biosecurity has defined DURC as «life sciences research that, based on current understanding, can be reasonably anticipated to provide knowledge, information, products, or technologies that could be directly misapplied to pose a significant threat with broad potential consequences to public health and safety, agricultural crops and other plants, animals, the environment, materiel, or national security».

«Significant increases in summer temperatures will affect the carbon cycling in the lakes, with potential consequences on atmospheric carbon dioxide levels and the Earth's climate,» he added.

«If people continue to exercise their choices as they are at present and there are no other significant changes, the resulting traffic growth would have unacceptable consequences for both the environment and the economy of the country and could be very difficult to reconcile with overall sustainable development goals.»

Individual DNA bases can be chemically modified, with significant functional consequences.

But a new study from the Woods Hole Oceanographic Institution (WHOI) suggests these changes are themselves shifting in unexpected ways, with potentially significant consequences for the ocean and climate.

The early childhood field should therefore combine cognitive - linguistic enrichment with greater attention to preventing, reducing, or mitigating the consequences of significant adversity on the developing brain.

Perhaps it's one in a thousand, and that's significant when you're dealing with consequences this big.»

«Exploratory analyses of several secondary outcomes indicated that the sedation protocol was associated with a difference in patients» sedation experience; patients in the intervention group were able to be safely managed in a more awake and calm state while intubated, receiving fewer days of opioid exposure and fewer sedative classes without an increase in inadequate pain or sedation management or clinically significant iatrogenic [consequence of treatment] withdrawal compared with patients receiving usual care, but they experienced more days with reported pain and agitation, suggesting a complex relationship among wakefulness, pain, and agitation,» the authors write.

«Drawing on collaborative expertise in synthetic chemistry, molecular biology and translational medicine, the team has produced findings with significant potential to reduce inflammation, a critical driver of the devastating consequences of obesity - related diseases,» she said.

Fall and fall - related injuries are common among elderly individuals, with significant socioeconomic consequences for individuals and society, and women are affected more than men due to the decrease in female sex hormone production.»

As a consequence, bardoxolone has a complicated pharmacological and toxicological profile with significant clinical safety problems.

The most significant outcome of the research was that cortical abnormalities which take place in individuals with migraine are a consequence of the balance between an intrinsic predisposition, as indicated by modification of cortical surface area, and processes related to disease, as indicated by abnormalities of cortical thickness.

Compliance is however low, as some find making use of a mask through the night prohibitively uncomfortable, resulting in a lot of people having untreated obstructive sleep apnea together with its significant health consequences.

It is not clear that lower levels of 25 (OH) D for persons with dark skin have significant health consequences.

Being infected with the herpes virus may not have serious consequences for your health, but it can have a significant impact on your all aspects of life.