The Vijayanand lab has developed a number of genomics (transcriptomic, single - cell and epigenomic) and immunological assays to enable research
with small numbers of cells and small - volume clinical samples.
Not exact matches
Breastfeeding is contraindicated in infants
with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis disease or are human T -
cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a
small number of other medications until they clear the milk109, 110; mothers who are using drugs
of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear
of lesions).
In 2014, Christiano and other CUMC researchers identified the immune
cells responsible for destroying hair follicles in people
with alopecia areata and tested an FDA - approved drug that led to complete hair regrowth in a
small number of patients.
He wants to raid a fund for workers compensation,
with the promise
of reforming the entire system, and raise a
small number of fees, including higher fines for texting or using a
cell phone while driving.
(Previously, scientists had used CRISPR / Cas9 to repair mutations that affect
smaller numbers of people
with Duchenne, and in
cell types that weren't necessarily clinically relevant.)
«We can work
with any embryonic stem
cell line from any source and are not restricted to working
with the very
small number of federally approved lines as is the case for researchers in the United States,» says Minger.
In the study, the researchers detected a very
small number of SIV infected
cells in the gut within initial 2.5 days
of viral infection; however, the inflammatory response to the virus was playing havoc
with the gut lining.
When comparing the
numbers of cardiac stem
cells in previously infected adult mice
with uninfected ones, the researchers found significantly
smaller numbers in the infected mice.
When a mother says that she is «always
with» her children, it is literally true: Scientists recently found that a
small number of maternal
cells can persist in a woman's offspring for decades or longer.
Koyuncu discovered this when she infected isolated axons
with a
small number of virus particles, which would normally travel to the
cell bodies and be silenced, while simultaneously exposing the
cell bodies to a large
number of inactivated virus particles that have been dosed
with ultraviolet radiation (UV).
In it, the team transferred a
small number of iNKT
cells lacking Tet2 / 3 from mutant mice into adult mice
with a robust immune system.
In the coming months a
small number of patients will be transplanted
with fetal
cells in Lund, Sweden and Cambridge, UK.
As outlined below, we used a microfluidic quantitative PCR (qPCR) system to elucidate the gene expression profiles
of individual human oocytes and
small numbers of cumulus
cells using a combination
of a large
number of samples and targets [12], and then extended our studies via the use
of parthenogenesis, in conjunction
with gene expression profiling, as a functional assay
of cytoplasmic maturation
of oocytes.
Characteristic neuropathological findings were focal depletion
of diffuse and neuritic plaques, but not
of amyloid angiopathy, and the presence
of small numbers of extremely dense (collapsed) plaques surrounded by active microglia, and multinucleated giant
cells filled
with dense Abeta42 and Abeta40, in addition to severe
small cerebral blood vessel disease and multiple cortical hemorrhages.
This BaF3 phe116 almost completely fails to proliferate and activate STATs in response to IL - 9.15 However, upon prolonged culture
with IL - 9, a
small number of cells manage to survive and even proliferate, allowing an IL -9-dependent
cell line (BaF3 phe116 / 9) to be selected.14 In contrast to parental BaF3 phe116
cells, those IL -9-selected
cells could progress to autonomous
cells (BaF3 Aut) after a second selection step in the absence
of cytokine.
In a series
of electrophysiological studies, Zoghbi's team further found that neurons from animals
with depleted MECP2 levels have reduced electrical activity due to a
smaller number of excitatory synapses, whereas
cells from animals carrying an extra copy
of the gene have increased electrical activity because
of an increase in synapse
number.
Piperine also interferes
with inflammatory signaling mechanisms and inhibits pro-inflammatory cytokines, which are
small proteins secreted by some
cells and linked
with a
number of degenerative diseases.