Sentences with phrase «with small tumors»

Cats with small tumors located on the lower jaw (mandible) that are treated with surgery have a better chance of surviving for one year; however, most will still eventually succumb to the disease.

Of the 82 treated patients with small tumors, 96 percent (79 of 82) have had no recurrence more than three years after treatment, and 80 percent (28 of 35) of those with mid-size tumors also have had no recurrence.

Not exact matches

The targeted radiotherapy shrank tumors for 71 % of patients who had already failed standard chemotherapy, but these results came from a small trial that started with 30 patients and then added another 20 after positive data started rolling in.

«Particularly in such patients with underlying CKD, our modeling results support the integration of renal tumor anatomic features at cross-sectional imaging into decision making for treatment of small renal masses and may be used to provide a patient - centered framework for selection of optimal candidates for ablative therapy,» Kang said.

Led by Stella K. Kang, a radiologist with the Department of Radiology at the New York School of Medicine, the study was designed to compare the effectiveness of a treatment algorithm for small renal tumors incorporating the nephrometry score, a renal tumor anatomy scoring system developed by urologists, with the current standard of uniformly recommended partial nephrectomy in patients with mild - to - moderate chronic kidney disease (CKD).

But x-rays are not good at spotting tiny tumors, partly because of a lack of contrast and partly because the calcifications associated with tumors are much smaller than benign deposits and therefore easy to overlook.

Small populations of adult stem cells with somewhat limited developmental potential are responsible for the body's ability to heal injuries and replace worn out cells and tissues, and evidence is growing that rare cancer stem cells are responsible for the uncontrolled growth of some malignant tumors, including glioblastoma.

Northwestern Medicine scientists have identified a small RNA molecule called miR - 182 that can suppress cancer - causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor.

When injected with cancer cells, animals housed there developed tumors 80 % smaller than those in control mice, or no tumors at all.

Our job now is to figure out how to make immunotherapy effective against those tumors with small numbers of mutations.

«Even a small amount of infection with oHSV appears to be enough to trigger an immune response to the tumor.»

A tumor treated with verteporfin (right) is much smaller and much of the structure of the mouse's eye is visible.

Although surgery that is confined to removing just a small tumor (loco - regional treatment) is generally considered to be low risk, we have previously demonstrated that the proportion of patients who develop postoperative complications strongly increases with age and increasing numbers of other diseases or conditions that they may have.

In contrast, the LDL - DHA rats had smaller, pale tumors with poor blood supply.

A global analysis of metabolites and small molecules in urine samples from patients with adrenal cancer has identified four biochemicals that, when measured together, can distinguish malignant from benign adrenal tumors, according to study results presented at the 2015 Annual Clinical Congress of the American College of Surgeons.

At worst we would end up with a few little pebble tumors, small balls of abnormal cells that had exhausted their ability to grow, no more life - threatening than a mole or a small cyst.

«We wanted to utilize platelets» intrinsic tendencies to accumulate at wounds and to interact with circulating tumor cells, for targeted delivery of immune checkpoint inhibitors» said Gu, «Interestingly, we found the antibody can be promoted to release from activated platelets in the surgical site, due to generation of small platelet - derived microparticles upon the platelet activation.

The approach was most successful in making a difference in samples from the two patients in which the smaller - sized tumor DNA was not readily apparent, which may represent patients with low tumor burden and previously difficult to detect circulating tumor DNA.

The study showed that mice implanted with breast cancer cells lacking the protein developed small, self - contained tumors consisting of cells that didn't leave the tumor.

But in at least one case, a small tumor merged with the cells lining the faux blood vessel.

After ten days of PDT treatment, the tumors were found to be far smaller than comparative groups not treated with light.

This is where small molecule therapeutics could be developed to interfere with the signals and suppress tumor growth.

«We showed with this technique that we can detect very tiny tumors of just a few hundred cells,» Lu said, adding that the study pushed imaging boundaries, revealing smaller cancers than can be detected with current clinical imaging modalities.

In patients likely to have surgery, close, active monitoring of small renal tumors confined to the kidneys is associated with low rates of tumor growth or death, according to a study by a researcher at the Icahn School of Medicine at Mount Sinai published in the September issue of The Journal of Urology.

He was part of a team that recognized that only about 10 % of patients with NSCLC responded to the small molecule erlotinib — those whose tumors harbored mutations in the gene encoding EGFR.

Results showed that tumor cells containing the protein carried anywhere from 10 to 17 times fewer breast stem cells, and tumors grown from the injected cells were about three times smaller than those in mice who had received tumor cells with depleted levels of HOXA5.

Using a very sensitive DNA analysis technique that can also be employed when only very small amounts of DNA from old tissue are available, the researchers could compare the two current cell lines with the tumor from which the cell line was established.

In fact, the mice that received the complete nanomedicine package had smaller tumors and longer lifespans than their counterparts injected with saline, nanoparticles without the drug, the drug alone, and nanoparticles with the drug but without the targeting aptamers.

Among lung cancer patients; suicide SMR was higher in males (SMR = 8.8), Asians (SMR = 13.7), widowed patients (SMR = 11.6), older patients (70 - 75 years; SMR = 12), patients with undifferentiated tumors (SMR 8.6) or small cell lung carcinoma (SCLC) histology (SMR = 11.2), patients presenting with metastatic disease (SMR = 13.9) and in patients who refused to receive surgical treatment (SMR = 13).

Dr Jeremy Thomas, a consultant pathologist at the Western General Hospital, Edinburgh, UK, told the European Breast Cancer Conference that although the majority of women with DCIS received the correct surgery for their disease, large numbers of women were undergoing mastectomy for DCIS either as a result of failed breast conservation surgery or for tumors that turned out to be smaller than 20 mm in diameter and therefore should normally have had a lumpectomy rather than a mastectomy.

The total number of women who had mastectomies, including those for whom mastectomy was the first course of action as well as those who had failed breast conservation, was 2,479; of these, 510 (21 %) had mastectomies for tumors smaller than 20 mm in diameter, which would normally have been better treated with a lumpectomy.

Pre-malignant aneuploid cells grew more slowly and formed smaller tumors than comparable cells with normal chromosome number.»

The study also points to an increased incidence of tumors compared with those not operated on, but there the risks remained very small.

VIC - 008 is a fusion protein combining an immune - activating protein from the tuberculosis bacteria with a small antibody fragment targeting mesothelin, a protein expressed in several types of tumor — including mesothelioma, pancreatic and ovarian cancer.

• A patient's undifferentiated small bowel sarcoma was found to contain a KIT gene deletion, resulting in a revised diagnosis of GIST (gastrointestinal stromal tumor) that was successfully treated with imatinib.

A tumor treated with verteporfin (right) is smaller and much of the structure of the mouse's eye is visible.

In fact, large human liver cancer tumors on comparatively small mice started regressing about 20 days after treatment, and were eradicated by day 41 with the help of one of the targeted receptors.

Adding the monoclonal antibody drug trastuzumab — already used to treat certain breast cancers — to the chemotherapy regimen of women with a rare form of uterine cancer lengthens the amount of time their tumors are kept from growing, according to Johns Hopkins Medicine researchers conducting a small phase II trial of the regimen, testing its safety and value.

Can tumors be detected when they are two to three orders of magnitude smaller than those currently detected with in vivo imaging modalities?

Finding cancer early can improve a patient's chances for survival, but small tumors can be difficult to see with scanning techniques such as magnetic resonance...

But as fewer and fewer women were diagnosed with large breast tumors, pre-op chemo began to be used in patients with smaller cancers, too, in the hope that it would extend survival.

He performed the first of these inoculations in 1891, on a patient named Zola, an Italian immigrant with a tumor «the size of a small hen's egg» in his right tonsil, who likely had only weeks to live.

In 12 mice, MRI was able to detect the one relatively large tumor, 17 out of 18 small tumors that were smaller than a millimeter, and 13 out of 16 milk ducts that were distended with carcinoma in situ, including some tumors less than 300 microns in width, about one - third of a millimeter.

Rather, each tumor contains a small subset of cells with stem cell - like capacities that are responsible for initiating and sustaining tumor growth, while the bulk of the tumor cells lacks this ability.

Among married patients studied, almost 47 percent had the smallest, earliest - stage tumors compared with 43... -LSB-...]

When they blocked IKK2 activity in the mice with lung cancer, the mice had smaller tumors and lived longer, suggesting that the enzyme is necessary for NF - KB to stimulate tumor growth.

The researchers found that non-Hispanic white women were more likely to have smaller tumors, and more likely to have the less - aggressive HR + / HER2 - subtype of breast cancer, compared with African - American women, who were more likely to have large tumors, more likely to have the aggressive triple - negative breast cancer, and 40 to 70 percent more likely to be diagnosed at stage 4 of all subtypes of breast cancer.

The tumors formed in mice co-treated with chidamide and decitabine were significantly smaller than those that formed in untreated animals or those treated with the single agents, starting from 15 days of treatment (Figure 4C, left panel), as visualized by 18F - fluorodeoxyglucose small - animal positron emission tomography — computed tomography at 21 days of treatment (Figure 4C, right panel).

«We also identified a way to inhibit the SOX9 stabilization by treating the tumors with small molecular drugs, which made them less resistant to chemotherapy again.»

Mice injected with a strain of the Zika virus lived longer and were measured to have smaller tumors than the control group, which was injected with saltwater.