But as fewer and fewer women were diagnosed with large breast tumors, pre-op chemo began to be used in patients
with smaller cancers, too, in the hope that it would extend survival.
Not exact matches
There's a reason Conrad is especially qualified to navigate
small businesses through the maze of health benefits: While at Amgen, he was diagnosed
with testicular
cancer, and the experience gave him profound insights into the byzantine workings of the American healthcare system.
His exposed torso is peppered
with small holes through which
cancer surgery specialist Dr. James Sullivan and his team insert their medical instruments.
Wapiyapi is a
small, Colorado - based summer camp for kids
with cancer and their siblings.
My apology comes
with a
small caveat, which is that ipilimumab (or Yervoy, as it has been branded) was not approved for prostate
cancer.
So when a venture capitalist called last fall asking her to lead a
small cancer startup, she jumped at the opportunity to focus on a single drug —
with no bureaucracy or politics.
From
cancer research and materials science to psychological profiles, these new data sets will even
smaller players to innovate and compete
with much larger organizations.
With lung
cancer, for example, it wants to be able to resolve whether a test shows non-
small-cell lung carcinoma or
small cell lung carcinoma.
His companion for over thirty years was a woman old enough to be his mother; and when she died it was not long before, like a Pavlovian dog trained to lacerate his heart
with the same emotional experiences, he, married a woman whose circumstances were exactly parallel to those of his own mother in 1908 — a woman dying of
cancer who had two
small sons.»
When I had surgery for my
cancer last March, my brother in Texas who is a fundamentalist «christian» who preaches at how his little group has the Truth & the rest of us need to fall in line
with what his church teaches sent me a
small note saying he was praying for me before the surgery.
I probably want to say more, but I have to go help my wife
with her treatments for
cancer where something
smaller than her and inside is trying to control her and we are seeking to put things back in balance.
Participants
with cancer whom the research team randomly allocated to the experimental group to receive remote intercessory prayer showed
small but significant improvements in spiritual well - being.
Most large studies have found only a very
small decrease in risk of colon
cancer with the consumption of higher levels of dietary fiber and no decrease in risk of colon
cancer recurrence, according to the University of Maryland Medical Center.
Cancers associated
with coeliac disease are
small bowel
cancer,
small bowel lymphoma and Hodgkin lymphoma.
How can a memoir about tragic death (from
cancer, on the cusp of 40,
with two
small children) be so vibrantly about life itself?
Given questions about how long the vaccine is effective for, she questioned the efficacy of giving shots to girls as young as 11 years old in parts of the world (such as the U.S.) where women regularly undergo safety Pap screening repeatedly over their lifetimes, saying that the chances of their contracting cervical
cancer may be less than the «
small» risks associated
with the vaccine.
In another meta - study (compiling data from 47
smaller studies) published in 2002, more than 50,000 women
with breast
cancer and nearly 97,000 women without the disease from 30 countries were studied.
The UK Childhood
Cancer Study investigators23 published in 2001 a study that provided 1636 leukemia cases and indicated a weak evidence of borderline statistical significance that ever (compared
with never) having been breastfed was associated
with a
small reduction in leukemia risk (OR, 0.89; 95 % CI, 0.84 - 1.00).
Even
small projects
with other countries contribute important information on how genetic backgrounds and cultural factors such as diet affect
cancer development, he adds.
Inflicting less collateral damage to surrounding organs and healthy tissues, it can minimize side effects and increase cure rates for some
cancers — just what patients
with small bodies like Jonathan need.
Approximately one year after successful treatment
with cytotoxic chemotherapy and radiotherapy, patients
with advanced
Small Cell Lung
Cancer (SCLC), which primarily affects heavy smokers, generally relapse
with recurrence of tumours that are resistant to further chemotherapy.
Not that there are many complaints from pediatricians or parents of the relatively
small number of children who develop uncommon
cancers best treated
with proton therapy.
Small populations of adult stem cells
with somewhat limited developmental potential are responsible for the body's ability to heal injuries and replace worn out cells and tissues, and evidence is growing that rare
cancer stem cells are responsible for the uncontrolled growth of some malignant tumors, including glioblastoma.
Northwestern Medicine scientists have identified a
small RNA molecule called miR - 182 that can suppress
cancer - causing genes in mice
with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor.
The abstract title was: Attempt to Validate Drug Repositioning for Metastatic
Small Cell Lung
Cancer (SCLC) Therapy Identifies Statins Associated
with Survival Benefit.?
«For an individual, the risk of developing colorectal
cancer because of their consumption of processed meat remains
small, but this risk increases
with the amount of meat consumed,» says Dr Kurt Straif, head of the IARC monographs programme.
When injected
with cancer cells, animals housed there developed tumors 80 %
smaller than those in control mice, or no tumors at all.
Therefore, a novel therapeutic approach in inflammatory breast
cancer could involve a combination of conventional chemotherapy
with small - molecule inhibitors of the Cdk2 cell cycle kinase.
The abnormal immune response to gluten damages the
small intestine and is associated
with gastrointestinal symptoms including vomiting and diarrhea, lethargy, and an increased risk of osteoporosis and
cancer.
PARP inhibitors have shown efficacy for a
small group of patients
with breast
cancer with inherited mutations in BRCA genes, but have failed in the more aggressive triple - negative disease.
The actual disparity in number of cases between the two groups was
small,
with 129 lung
cancers in all, and the trial wasn't set up to study that disease.
The authors note that prior studies have reported elevated levels of distress among people
with cancer, but they vary in quality due to
small sample sizes, different diagnostic criteria and assessment standards, and an over-representation of women
with breast
cancer.
Researchers only discovered this process in the late 1990s, but they've already begun dozens of clinical trials to gauge whether infusing patients
with these
small RNAs works against a range of diseases, from lung infections to liver
cancer to age - related macular degeneration, a sight - stealing condition that mainly affects people over the age of 50.
A global analysis of metabolites and
small molecules in urine samples from patients
with adrenal
cancer has identified four biochemicals that, when measured together, can distinguish malignant from benign adrenal tumors, according to study results presented at the 2015 Annual Clinical Congress of the American College of Surgeons.
In a study that included children and young adults
with relapsed or refractory
cancer, incorporation of integrative clinical genomic sequencing data into clinical management was feasible, revealed potentially actionable findings in nearly half of the patients, and was associated
with change in treatment and family genetics counseling for a
small proportion of patients, according to a study in the September 1 issue of JAMA.
siRNAs are very
small molecules that carry genetic information to cells, but unlike DNA that can turn genes on, siRNA interferes
with the production of particular proteins and can turn
cancer genes off.
«Pelvic RT after chemotherapy may be more beneficial in treating this form of ovarian
cancer compared
with other types,» Dr.
Small said.
He's also likely to spur the FDA to follow the course laid out by agency
cancer czar Richard Pazdur in speeding new approvals, possibly setting up a special unit aimed at orphan drugs to hasten OKs
with smaller, better designed clinical trials.
«The size of the relation is no
smaller than the relation between smoking and lung
cancer,» says Leonard Eron, a University of Michigan psychologist who co-authored a similar study in 1986
with L. Rowell Huesmann.
Those are
small potatoes compared
with obesity, Type 2 diabetes, osteoporosis, heart disease and many
cancers also on the rise in the developed and developing parts of the world.
The study showed that mice implanted
with breast
cancer cells lacking the protein developed
small, self - contained tumors consisting of cells that didn't leave the tumor.
«By also binding
with the magnetically tagged peptide, the biomarker is enhanced, generating enough signal for MRI detection of
small, high - risk
cancer and micromestastases.»
Researchers
with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) have identified the microenvironment surrounding microvasculature — the
small blood vessels that transport blood within tissues — as a niche where dormant
cancer cells reside.
Dr Lu concluded: «Only a
small proportion of patients committed suicide or attempted suicide immediately after being diagnosed
with cancer.
A few
small trials in the past 5 years — for pancreatic and ovarian
cancer — hinted that IV vitamin C treatment combined
with chemotherapy can extend
cancer survival.
The researchers tested two anti-CK2 drugs for their ability to stimulate the production of new brown fat in mice: a new
small - molecule CK2 - blocker called silmitasertib (CX - 4945), which is already in clinical trials as a
cancer therapeutic; and a more precise next - generation antisense oligonucleotide (ASO) drug developed in collaboration
with Isis Pharmaceuticals, which eliminates CK2 by blocking the RNA instructions cells use to produce it.
«We showed
with this technique that we can detect very tiny tumors of just a few hundred cells,» Lu said, adding that the study pushed imaging boundaries, revealing
smaller cancers than can be detected
with current clinical imaging modalities.
He secured a
small grant to do a rigorous investigation comparing
cancer rates in the Laron syndrome patients
with those of their relatives of normal height.
The researchers also uncovered a
small increase in the risk of pancreatic
cancer in patients
with severe periodontitis.
Recent years have seen extensive research on the genetics of prostate
cancer,
with over a hundred mutations identified, however most of these are only present in a
small number of men.