[10] Complete responses (CRs) and partial responses (PRs) were reported in 3.2 % and 8.7 % of patients, respectively,
with stable disease (SD) in 25 % of the two patient cohorts combined.
«The response rate with this drug is about 30 % — plus you get another 30 %
with stable disease.
Within the mucosal melanoma subgroup, there were 8 partial responses (23 %) and 7 patients
with stable disease (20 %), but no complete responses were observed.
This could greatly expand the utility of hair restoration surgery to women and to younger patients — now it is largely restricted to the treatment of male - pattern baldness in patients
with stable disease.»
Not exact matches
This is perfect for anyone dealing
with chronic
disease that wants to keep their blood sugar
stable and reduce inflammation.
Caregiver duties and responsibilities can include: Assisting
with personal care: bathing and grooming, dressing, toileting, and exercise Basic food preparation: preparing meals, shopping, housekeeping, laundry, and other errands General health care: overseeing medication and prescriptions usage, appointment reminders and administering medicine Mobility assistance: help
with getting in and out of a wheelchair, car or shower Personal supervision: providing constant companionship and general supervision Transportation: driving to and from activities, running errands, and help getting in and out of wheelchair - accessible vehicle Emotional support: being a
stable companion and supporter in all matters personal, health - related and emotional Care for the elderly: orienting or grounding someone
with Alzheimer s
disease or dementia, relaying information from a doctor to family members Back - up care (or respite) services: providing other caregivers a break Home organization: help
with organizing
«We found that galeterone resulted in meaningful PSA declines in patients
with metastatic CRPC, and imaging showed that the
disease was
stable or had responded to the drug,» Prof Taplin will say.
While the
disease remains a modest threat in rural, undeveloped areas, Green warns that our current
stable relationship
with plague in the developed world is only as good as our control of urban rodent populations.
Populations of this unique species, currently known as highly threatened, were previously considered to have remained relatively
stable in the face of the
disease that has ravaged many amphibian species worldwide, but the frogs may have been infected over a decade ago,
with the impacts only recently observed.
The clear result of this clinical study — that the combination reduced strokes, heart attacks and cardiovascular death by practically 25 per cent compared to either drug alone in both patients
with stable coronary or peripheral artery
disease — caused the clinical trial to be stopped early, after 23 months, in February 2017.
Although aspirin reduces the risk of major cardiovascular events by 19 per cent, a more effective antithrombotic strategy could have major benefits for the large population of patients
with stable cardiovascular
disease.
In a bid to get round some of these issues the researchers looked at the association between occasional or persistent mental distress and the risk of death in 950 people
with stable coronary heart
disease who were between 31 and 74 years old.
This study of 27 patients indicates that temsirolimus, an mTOR inhibitor, and HCQ is safe and tolerable, blocks autophagy, and had significant antitumor activity; researchers observed
stable disease in 75 percent of those patients
with metastatic melanoma.
And they go on to say: «These findings suggest that in patients
with stable [coronary heart
disease], long term mortality risk is related to the cumulative burden of psychological distress.»
Further experiments revealed that modulating activity of ATP synthase
with J147 changes the levels of a number of other molecules - including levels of ATP itself - and leads to healthier, more
stable mitochondria throughout aging and in
disease.
Persistent moderate to severe mental distress is linked to a significantly heightened risk of death among patients
with stable coronary heart
disease, finds research published online in the journal Heart.
An analysis of diagnostic test results from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial — in which patients
with stable chest pain were randomized to either anatomic or functional testing as an initial diagnostic strategy — showed that the presence and extent of coronary artery
disease detected by CT angiography better predicted the risk for future cardiac events than did measures of exercise tolerance or restricted blood flow to the heart muscle.
In previous studies, the same group along
with others had demonstrated that microRNAs (miRNAs) produced by eukaryotic cells and viruses are present in human blood in highly
stable, cell - free forms and these so called circulating miRNAs can serve as non-invasive biomarkers for the early diagnosis of various
diseases, including viral
diseases.
Young women
with stable coronary heart
disease are more likely than men to have reduced blood flow to the heart if they're under emotional stress, but not physical stress, according to research presented at the American Heart Association's Scientific Sessions 2014.
«While the median survival rate for patients without distant metastasis was nearly a year - and - a-half
with this treatment, there was one patient whose
disease remained clinically
stable for nearly three years.
That association didn't change for patients who were previously diagnosed
with depression before their heart
disease diagnosis or for patients whose angiograms were performed for various reasons, which included
stable angina, unstable angina, or heart attack.
To treat chronic liver
disease, the cells would have to be
stable for at least five years, the average survival period for those
with the
disease.
Many children
with liver
diseases don't grow like they're supposed to, so getting them nutritionally
stable will get them ready for transplant sooner and avoid complications following transplant.
When examined alone, the ASPS patients had a clinical benefit rate of 83 %, as two patients had
stable disease along
with the three partial responses.
Further experiments revealed that modulating activity of ATP synthase
with J147 changes the levels of a number of other molecules — including levels of ATP itself — and leads to healthier, more
stable mitochondria throughout aging and in
disease.
Following completion of a massive epitope discovery effort (also supported by an HHS contract), current work on MTB includes development of tools to isolate MTB - specific T cells (supported by the Gates Foundation) and identifying T cell signatures that distinguish three possible infection states: cleared infection,
stable latent infection, and latent infection
with high risk of progression to
disease (in conjunction
with a large consortium led by Henry Blumberg at Emory University).
Most of the patients had a long CFS
disease duration, also
with a
stable or worsening clinical course the last year before study entry.
«The phase 2 study has provided some early evidence that patients
with recurrent
disease who get the vaccine may be
stable for a long period,» Ghamande said.
Participants were divided into four groups: those diagnosed
with probable Alzheimer's when entering the study, healthy controls
with no sign of dementia, individuals
with mild cognitive impairment that remained
stable over the two to three years for which scans were available, and those
with mild cognitive impairment that progressed to Alzheimer's
disease during the study.
There is almost always time to get a second opinion and to read about heart
disease prevention and lifestyle change programs for patients
with chronic
stable angina.
A loved one dies, someone comes down
with an inexplicable
disease, we fall flat on our face in some unpredictable way... something happens to make us realize that these rules we're taught are based on a less - than -
stable foundation.
Enig says because of decisions made by the FDA to lump saturated fats and trans fats together, «we have a population that is terrified of healthy, natural fats found it dairy, meat, coconut and palm oils which are healthful and
stable to cook
with, [while] at the same time we have widespread obesity, runaway diabetes, increasing cancer, immune dysfunction and heart
disease rates.»
Today, however, there are many other individuals (men and women, young and old, children, and patients
with a
stable chronic
disease) whose main focus is on using weight training to improve or maintain strength.
Self sufficient, mentally
stable, drug and
disease free
with no tag along baggage.
Two more cases have been identified of horses
with the wild strain, that are not showing signs of neurologic
disease, and they are being treated at their home
stables in Polk County.
Although kidney
disease and heart
disease can not be cured, they can be significantly controlled
with medications and this will normally lead to a more
stable blood pressure level.
Animals
with kidney
disease can be
stable for long periods
with good treatment, but ultimately the
disease will progress.
This is particularly dangerous for people
with stable heart
disease, because it can trigger off cardiac arrhythmia or even a heart attack
Why is depression associated
with an increased risk in cardiovascular events in people
with stable coronary heart
disease?