Sentences with phrase «with subgroup analysis»

Lin, Y. S., Lin, L. C., and Lin, S. W. Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow - up of a double - blind randomized study with subgroup analysis.

On the basis of a metaanalysis of cohort studies with subgroup analysis by sex, both active and passive smoking is related to higher risk of developing T2DM in both men and women without known prominent sex differences (134).

The results of a metaanalysis of observational studies, with subgroup analysis by sex, presented that shift work was associated with greater diabetes risk in men (107).

We investigated substantial heterogeneity for all four outcomes with subgroup analyses for the following covariates: who delivered care, type of support, timing of support, background breastfeeding rate and number of postnatal contacts.

Not exact matches

We conducted an a priori subgroup analysis comparing risk of bias, results and conclusions of reviews with different industry sponsors (for example, cane and beet sugar industry sponsored reviews vs artificial sweetener industry sponsored reviews).

Subgroup analyses were undertaken for products with and without fruit, nuts and / or seeds.

In the subgroup analysis stratified by parity, there was an increased incidence of the primary outcome for nulliparous women in the planned home birth group (weighted incidence 9.3 per 1000 births, 95 % confidence interval 6.5 to 13.1) compared with the obstetric unit group (weighted incidence 5.3, 3.9 to 7.3).

Because race is a factor in breastfeeding duration among term infants (39 % of white US infants are breastfeeding at 6 months compared with 24 % of African American infants3) and because of the high incidence of premature births among African American women, we performed a subgroup analysis on African American subjects.

In our subgroup analysis of African American infants, at 12 weeks, African American mothers with peer counselors had odds of providing any breast milk 249 % greater than those for African American mothers without peer counselors (odds ratio, 3.59 [95 % confidence interval, 1.16 - 11.03]; P =.03)(Table 3).

The confidence intervals for this subgroup do not overlap with any other subgroup, but within - group heterogeneity for all subgroups remains very high, and we advise caution when interpreting this result (Analysis 6.2; test for subgroup differences: Chi ² = 13.78, df = 3 (P = 0.003), I ² = 78.2 %).

Therefore, for the review's four primary outcomes we carried out subgroup analysis to explore the impact of interventions involving different types of supporter (professional versus lay person, or both); types of support (face - to - face versus telephone support or both); timing of support (antenatal and postnatal versus postnatal alone); whether the support was proactive (scheduled contacts) or reactive (women needed to request support); and whether support interventions had similar effects in settings with different background breastfeeding initiation rates (low, medium or high background rates).

For cessation of exclusive breastfeeding at up to six months face - to - face interventions may be associated with greater effects than other types of support; however, very high within - group heterogeneity remains in the analysis, and we advise caution when interpreting this result (test for subgroup differences: Chi ² = 37.55, df = 2 (P <.00001, I ² = 94.7 %; Analysanalysis, and we advise caution when interpreting this result (test for subgroup differences: Chi ² = 37.55, df = 2 (P <.00001, I ² = 94.7 %; AnalysisAnalysis 3.2).

For cessation of exclusive breastfeeding at up to six months the treatment effect appears to be greater when the intervention was delivered by non-professionals (lay support) compared with professionals or mixed support (test for subgroup differences: Chi ² = 7.74, df = 2 (P = 0.02), I ² = 73.1 %; Analysis 2.2).

«On the other hand the US Food and Drug Administration has taken the more conservative approach which recognises that SQUIRE was designed for all - comers without prior selection, and this subgroup analysis is insufficient evidence to conclude that patients with EGFR negative tumours are not candidates.»

Patients with epidermal growth factor receptor (EGFR) expressing advanced squamous non-small-cell lung cancer benefit most from necitumumab added to gemcitabine and cisplatin chemotherapy, according to a subgroup analysis from the SQUIRE trial presented today at the European Lung Cancer Conference (ELCC) 2016 in Geneva, Switzerland.

Commenting on the findings, Prof Robert Pirker, programme director for lung cancer at the Vienna General Hospital in Vienna, Austria, not involved in the study, said: «This subgroup analysis shows that the effect of necitumumab was slightly greater in patients with EGFR expressing tumours than it was in the entire SQUIRE population.

«By combining the genetic analysis of a small population of immune cells from healthy skin with functional experiments we were able to define two subgroups of memory immune cell and in detail decipher / dissect how these cells behave in healthy and inflamed skin,» explains Liv Eidsmo, researcher at Karolinska Institutet's Department of Medicine.

Even though the primary results of a related study investigating the effects of music therapy with children with autism, do not show that music therapy works better than other therapies, subgroup analysis identified that children with childhood autism or coexisting intellectual disability improve to a greater extend from music therapy than children with another autism diagnosis.

In subgroup analyses, minority faculty development programs that were present for ≥ 5 years and had more components were associated with greater increases in underrepresented minority faculty representation.

Using analysis of variance, t - tests, or chi - square tests as appropriate, we compared the clinical characteristics among exposure groups and among subjects with World Trade Center cough according to prognostic subgroups: those with predominantly upper - airway symptoms (29 subjects) or lower - airway symptoms (95 subjects) or those with bronchial responsiveness (249 subjects).

The authors next took 997 tumors in the discovery set, integrated copy number and gene expression data, and performed clustering analyses to identify subgroups of tumors with distinct features and clinical outcomes.

Subgroup analyses showed benefit with the combination in all groups, with the exception of those with brain metastases at baseline, though this included a total of only 12 patients.

We are continuing this analysis as the leaders of the imprinting subgroup in GTEx, with particular interest in variable imprinting and molecular mechanisms of allelic silencing.

At Korean population level, the evening chronotype was more common in younger women and linked to metabolic diseases with sex dimorphism, independent of lifestyle and sleep duration in subgroup analysis.

In their latest study, researchers at La Jolla Institute for Allergy and Immunology (LJI) used single - cell transcriptome analysis to identify a hitherto unknown precursor for a poorly understood subgroup of killer T cells that is primarily found in humans with chronic viral infections.

Additional analyses favor the hypothesis that MEIS1 exhibits pleiotropy for insomnia and RLS and show that the observed association with insomnia complaints can not be explained only by the presence of an RLS subgroup within the cases.

Depending on the histological findings, a second round of targeted histological analyses of subgroup B mice may be undertaken with the objective of increasing the statistical significance of the observations.

We also performed subgroup meta - analyses by type of prevention (primary v secondary: in this study, trials involving healthy populations or patients with any specific disease except for cardiovascular disease were classified as primary prevention trials, and trials involving patients with cardiovascular disease were classified as secondary prevention trials), type of supplement by quality and dose (each supplement, vitamins only, antioxidants only, or antioxidants excluding vitamins), type of outcome (cardiovascular death, angina, fatal or non-fatal myocardial infarction, stroke, or transient ischaemic attack), type of outcome in each supplement, type of study design (randomised, double blind, placebo controlled trial v open label, randomised controlled trial), methodological quality (high v low), duration of treatment (< 5 years v ≥ 5 years), funding source (pharmaceutical industry v independent organisation), provider of supplements (pharmaceutical industry v not pharmaceutical industry), type of control (placebo v no placebo), number of participants (≥ 10000 v < 10000), and supplements given singly or in combination with other vitamin or antioxidant supplements by quality.

However, in subgroup analyses stratified by age, we found that the deletion allele was associated with increased risk for lung cancer among individuals < 50 years of age (OR 2.17, CI 1.19 - 3.97), and that the association was gradually reduced with increasing age (p = 0.01).

There were also no clear differences in the association between statin use and outcomes in analyses stratified by age older or younger than 55, 60, 65, or 70 years, with very similar estimates from 7 trials (eTable 6 in the Supplement).14, 19,20,26,29,31,35 None of the trials that enrolled patients older than 75 years18, 20,22,23,27,29 reported results in this subgroup.

Umbrella reviews systematically search, organise, and evaluate existing evidence from multiple systematic reviews and / or meta - analyses on all health outcomes associated with a particular exposure.11 We conducted a review of coffee consumption and multiple health outcomes by systematically searching for meta - analyses in which coffee consumption was all or part of the exposure of interest or where coffee consumption had been part of a subgroup analysis.

It has been confirmed that coffee consumption is associated with a reduced risk of hepatocellular, kidney, and to a lesser extent, premenopausal breast and colorectal cancers, while it is unrelated to prostate, pancreas and ovary cancers.n subgroup analyses, we note that, for bladder, breast, buccal and pharyngeal, colorectal, endometrial, esophageal, hepatocellular, leukemic, pancreatic, and prostate cancers, there appears to be an inverse association.

Our ability to conduct these subgroup analyses is further constrained by the relative homogeneity of the students in our sample, with most being white and in advanced classes.

This analysis includes the entire class of 2013, as well as additional information on trends and the performance of subgroups, including students with disabilities.

At a minimum, discipline reports should include data on all significant disciplinary actions that list types of infractions (with specific and standardized definitions), track instructional time missed, and allow cross-tabulation and analysis of data by subgroup.

For my nine insurance subgroups (bigger than Mr. Spehar's analysis — I cover them all), almost all of the intercept terms are different than zero with statistical significance.

Subgroup analyses contrasting the pre-group interviews of fathers who endorsed higher (n = 9) versus lower (n = 5) levels of symptoms revealed that those with greater symptomatology expressed more themes related to fear of committing to the program.

Subgroup analyses: We will examine whether there is evidence that the intervention effect is modified for subgroups within the trial participants using tests of interaction between intervention and child and family factors as follows: parity (first - born vs other), antenatal risks (2 vs 3 or more risk factors at screening), maternal mental health at baseline (high vs low score) 18, 62, 63 and self - efficacy at baseline (poor vs normal mastery) 35 using the regression models described above with additional terms for interaction between subgroup and trSubgroup analyses: We will examine whether there is evidence that the intervention effect is modified for subgroups within the trial participants using tests of interaction between intervention and child and family factors as follows: parity (first - born vs other), antenatal risks (2 vs 3 or more risk factors at screening), maternal mental health at baseline (high vs low score) 18, 62, 63 and self - efficacy at baseline (poor vs normal mastery) 35 using the regression models described above with additional terms for interaction between subgroup and trsubgroup and trial arm.

Multiple regression analysis models with dummy variables assessed the effects of IPPE, MSPSS, TAS - 20, Social Sharing, and Mental Rumination on GDS across the subgroups of participants.

For example, a tobacco - focused review which included any intervention type, classified interventions with a component of resilience content into different subgroups such as social competence or social influence interventions, finding evidence for both broad intervention approaches.6 For the alcohol - focused review, only universal interventions were included with such interventions grouped according to whether they targeted alcohol alone or targeted multiple substance types.5 While meta - analysis was not conducted due to the heterogeneity of studies, the review concluded that some psychosocial and developmental prevention programmes were effective.

Notes: The study was not powered to show gender - specific differences; therefore these subgroup analyses should be interpreted with caution.

Additional subgroup analyses revealed that the program effect was higher in the subgroup without alcohol or nutrition instruction than in the group with instruction (composite measure alcohol d = 0.22 vs. 0.02; composite measure breakfast d = 0.16 vs. − 0.14).

To identify different subgroups of adolescents with psychopathic traits, Latent Class Analyses (LCA; Muthén and Muthén 1998 — 2006) were performed using standardized scores (z - scores).

It is important to identify potential subgroups of adolescents with differing levels of social anxiety over time because with this information a richer analysis of potential variables that are associated with continuity or emergence of social anxiety during adolescence is possible.