Sentences with phrase «with substantial risk»

A second issue with the Court's judgment that may be more significant is its suggestion that the bright line rule and the substantial risk principle are distinct tests for identifying the existence of a conflict of interest, with the substantial risk principle applying in circumstances where the bright line rule has not been satisfied.

A driver can be held liable for Endangerment if he or she «recklessly endangers another person with a substantial risk of imminent death or physical injury.»

Treating dogs for heartworms carries with it a substantial risk, but, if your dog is in good health and the instructions of your veterinarian are followed, this will considerably reduce the possibility of serious complications.

[The very wealthy often own businesses with substantial risk.

Government bonds provided a real compounded return of only 1.6 % during 1900 - 2000, with substantial risk (standard deviation 10 %).

No one will give you way above market average returns with no substantial risks involved.

Not exact matches

Prior to founding Orcam, Mr. Roche ran a private investment partnership in which he generated substantial alpha (high risk adjusted returns) with no negative 12 month periods during one of the most turbulent periods in stock market history.

Releasing a report responding to Ceres — a group made up of institutional investors which has for years been pushing resource companies to disclose their carbon bubble risks — Exxon vice-president of corporate strategic planning William Colton said, «All of ExxonMobil's current hydrocarbon reserves will be needed, along with substantial future industry investments, to address global energy needs.»

Finally, right behind market fit and team problems, in terms of fatal startup failings, comes the substantial risks associated with strong competition (existing or emerging), which drives about 20 % of the new companies out of business.

In an interview, Bullard says he believes the Fed risks losing credibility with the public by ignoring the prices of goods that account for a substantial share of household spending.

Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government regulation over our business and the potential effects of new laws or regulations or changes in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.

Second, financial logic embodied in the celebrated Modigliani Miller theorem and suggested by common sense holds that substantial reductions in leverage, if achieved, should be associated with reduced volatility, reduced sensitivity to shocks and lower risk premiums.

Blockchain technology can cut out the substantial intermediary costs, security risks, and record keeping infrastructure traditionally associated with such applications resulting in reduced cost, fewer time delays and less human error.

Our long history has allowed us to build extensive databases of proprietary index, risk and ESG data, as well as accumulate valuable historical market data, which is difficult to replicate and provides us with a substantial competitive advantage.

Naturally, you can manage your risk easily with various tools enabled in trading, so most of the traders reach substantial gains over time.

Trading and investing in securities involves substantial risks and you should consult with a qualified financial professional before making any investment decision.

We believe that our pledging policy effectively mitigates the risk that forced sales of pledged shares could prompt a broader sell - off or further depress a declining stock price, while providing our officers and directors with reasonable flexibility to use their FedEx shares as collateral for loans for needed liquidity and encouraging them to retain substantial ownership of their shares.

Furthermore, because of the substantial amount of discovery required in connection with intellectual property litigation, there is a risk that some of our confidential information could be compromised by disclosure.

There is substantial risk associated with investing in any financial instrument.

«In the current situation, a further appreciation of the Swiss franc would constitute a very substantial threat to the Swiss economy, and would carry with it the risk of deflationary developments,» Jordan said at a conference in Zurich today.

Last week, Bank of America's (BOA) released their SEC annual report that also contained a mention of cryptocurrencies as a threat to their business, with the risk of competition described in very similar terms: «the widespread adoption of new technologies, including internet services, cryptocurrencies and payment systems, could require substantial expenditures to modify or adapt our existing products and services.»

As usual, I don't place too much emphasis on this sort of forecast, but to the extent that I make any comments at all about the outlook for 2006, the bottom line is this: 1) we can't rule out modest potential for stock appreciation, which would require the maintenance or expansion of already high price / peak earnings multiples; 2) we also should recognize an uncomfortably large potential for market losses, particularly given that the current bull market has now outlived the median and average bull, yet at higher valuations than most bulls have achieved, a flat yield curve with rising interest rate pressures, an extended period of internal divergence as measured by breadth and other market action, and complacency at best and excessive bullishness at worst, as measured by various sentiment indicators; 3) there is a moderate but still not compelling risk of an oncoming recession, which would become more of a factor if we observe a substantial widening of credit spreads and weakness in the ISM Purchasing Managers Index in the months ahead, and; 4) there remains substantial potential for U.S. dollar weakness coupled with «unexpectedly» persistent inflation pressures, particularly if we do observe economic weakness.

With interest rates still hovering near the lowest levels they've ever been in 5,000 + years of recorded human history, it's very difficult to achieve a significant investment return without taking on substantial risk.

Per the buy - sell agreement, the shares I received are subject to a vesting schedule AND substantial risk of forfeiture for certain circumstances which are concurrently covered under my employment agreement with Company A.

High Risk — Speculation (H / SPEC) High risk equities of companies with a short or unprofitable operating history, limited or less predictable revenues, very high risk associated with success, significant financial or legal issues, or a substantial risk / loss of princiRisk — Speculation (H / SPEC) High risk equities of companies with a short or unprofitable operating history, limited or less predictable revenues, very high risk associated with success, significant financial or legal issues, or a substantial risk / loss of princirisk equities of companies with a short or unprofitable operating history, limited or less predictable revenues, very high risk associated with success, significant financial or legal issues, or a substantial risk / loss of princirisk associated with success, significant financial or legal issues, or a substantial risk / loss of princirisk / loss of principal.

People who start new companies often risk a great deal with substantial investments in time and money to make their ideas a reality.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

It is customary and even ethically mandatory that experimentation that carries with it a substantial degree of risk to human subjects first be tested in an animal laboratory or, at the very least, on a computer model.

FI project aims to improve safeguarding in four EU countries through better engagement with fathers Serious Case Review summaries across the world (plus a substantial body of research) reveal that family professionals working with children at risk of harm commonly fail to engage well with men in families where there are safeguarding concerns.

Serious Case Review summaries across the world (plus a substantial body of research) reveal that family professionals working with children at risk of harm commonly fail to engage well with men in families where there are safeguarding concerns.

There is a substantial risk of neonatal death if the baby is born with chickenpox.

Regardless of the fact that there was no substantial connection between the timing of introducing solids to breastfed infants and their risk of preschool obesity, the study still urged parents to keep with the AAP's suggested timing for starting solids: About six months of age.

American Pediatrican Association has stated «Use of a pacifier is associated with a substantial reduction in the risk of SIDS».

Many of the epidural side effects mentioned below are not improved with low - dose or walking epidurals, because women using these techniques may still receive a substantial total dose of local anesthetic, especially when continuous infusions and / or patient - controlled boluses (single large doses) are used.34 The addition of opiate drugs in epidurals or CSEs can create further risks for the mother, such as pruritus (itching) and respiratory depression (see below).

They may be aware of the greater risk for mood disorders such as depression and anxiety associated with sleep loss; the substantial impairment in cognitive abilities such as sustained attention, short - term memory, information processing, and school performance; or the increased risk for motor vehicle accidents that accompanies lack of sleep.

Those risks could be substantial, according to Catherine Chavigny, R.N., a former certified nurse - midwife and the director of Related Health Professions and Nurse Affairs with the American Medical Association.

The substantial increase in risk occurs at 42 week onwards with a stillbirth rate of 1 in 1000 (Decker 2016).

My rationale was that we know there are risks associated with artificial breastmilk and substantial benefits to human milk, particularly breastfeeding relationships.

high risk of bias (e.g. numbers or reasons for missing data imbalanced across groups; «as treated» analysis done with substantial departure of intervention received from that assigned at randomisation);

What is often ignored by those who are opposed to bedsharing is that there is substantial evidence that children left in a crib in a room separate from their parents (the new «norm» in Western society) is associated with a large increased risk for SIDS, even when bedding and mattress and temperature are taken into account [5][6][7].

In Japan, a system of lifetime employment in many big businesses, a tradition of employer provided benefits such as housing in many cases, and a wage system in those kinds of businesses where workers receive a substantial share of their annual income in the form of an annual bonus whose size can be used to buffer good and bad years for a company sharing risks and rewards with workers instead of limiting the risks and rewards to an investor class, have contributed to low levels of income inequality in the Japanese economy relative to comparably developed countries with comparable levels of government spending on welfare state type programs in other countries.

Bacheller said the state appears to be taking a substantial risk with NexGen, given that the company is a start - up with no manufacturing or sales track record of its own.

The researchers caution that a more randomized and controlled clinical trial is needed before doctors can reliably use their cardiac imaging analysis routinely with patients, but if confirmed, they say the method should reduce ablation procedures unlikely to work, along with the procedures» substantial costs and complication risks.

These new findings, along with other recent studies, suggest that the risk for congenital heart defects in Down syndrome can come from several genes and environmental factors, in addition to the substantial risk from the extra chromosome 21.

The Lariat device received FDA 510 (k) class II (intermediate risk) clearance for soft tissue approximation in June 2006 based on stated «substantial equivalence» with other devices used to place sutures during laparoscopic surgeries or vein harvesting.

«While the value of large data sets in health care has undoubtedly been the subject of substantial hyperbole, our results add to a growing body of work indicating the feasibility of leveraging such data sets with standard computational tools to make predictions that may be applied to stratify risk.

Treatments such as behavioral therapies or continuous glucose - monitoring systems can prevent these events in many — but not all — people with this impaired awareness, leaving a substantial number of people at risk.

«Furthermore, a substantial elevation in PM2.5 may also serve as a nudge that reminds or alerts people to avoid areas and activities where other people may share an infection with them, to not touch their face with dirty hands, to be vigilant about washing their hands when reasonably possible or prudent, and to engage in other preventive behaviors that are known to reduce infection risk.»

Children from low - income families are at substantial risk in terms of their social - emotional and academic skills at school entry, with fewer than half considered ready for school at age 5.

«Across all countries a substantial number of people who inject drugs are living with HIV or HCV and are exposed to multiple adverse risk environments that increase health harms,» says UNSW's Professor Louisa Degenhardt, lead author of the paper reviewing prevalence of injecting drug use and HIV and Hepatitis in this population.