Sentences with phrase «with surrogate markers»
Support to date for the existence of an hypoxic niche in marrow blood stem cells came from indirect evidence such as expression of the hypoxia protein Hif - 1 and related genes and staining with surrogate markers of hypoxia.
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Abiraterone's ability to lower levels of prostate - specific antigen, a surrogate marker for prostate cancer, was slightly greater for patients in the low - dose with food group when measured at 12 weeks.
Cardiovascular phenotyping between the ages of 60 and 64 years with carotid intima media thickness (cIMT; a surrogate marker for cardiovascular events) was used to assess the effect of lifetime exposure to adiposity on cardiovascular risk factors.
Instead they measure surrogate markers — outcomes that are associated with a risk of disease — but not a bad outcome itself.
Most importantly, the three clinical intervention trials with colon polyp recurrence as an end point also failed to show a protective effect against this surrogate marker for colon cancer (Alberts et al., 2000; Bonithon - Kopp et al., 2000); Schatzkin et al., 2000).