Not exact matches
The connecting process (
synapse formation) is rapid during this year,
with brain activity becoming closer to adult than newborn by 12 months.
«This opens the door to follow the natural evolution of synaptic density
with normal aging and follow how drugs can alter synapses or
synapse formation.»
«Visualization of newly formed synapses
with unprecedented resolution: Researchers optimized a spatiotemporally controlled method to induce, visualize
synapse formation in cortical neurons.»
It interferes
with the production of a protein critical to
synapse formation during a brief period in early development when the brain is optimizing its ability to process sensory input.
For example, our discovery of HORMAD1 (Fig 2) and HORMAD2, two proteins that preferentially associate
with unpaired / unsynapsed meiotic chromosome cores / axes, allowed us to address how progression in meiosis is coordinated
with crossover
formation, and how meiotic checkpoints / quality control ensure that only those meiocytes progress in meiosis that correctly paired and
synapsed their homologous chromosomes.