The existence of this enzyme may account for the increased amount of adenosine 3», 5» monophosphate associated
with synaptic activity in the ganglion.
Not exact matches
Synaptic plasticity, the ability of neurons to alter the strength of their synaptic connections with activity and experience, is thought to play a critical role in memory
Synaptic plasticity, the ability of neurons to alter the strength of their
synaptic connections with activity and experience, is thought to play a critical role in memory
synaptic connections
with activity and experience, is thought to play a critical role in memory storage.
This finding is in accordance
with earlier animal model studies, which have shown that physical
activity increases the amount of growth factors in the brain and improves
synaptic plasticity.
As professor Holtmaat explains: «It is possible that sensory stimulation, when combined
with another
activity (motor
activity, for example), works better for strengthening
synaptic connections.»
The work combines remote control of action potential firing and
synaptic signaling combined
with imaging of
activity with genetically encoded calcium and voltage sensors and electrophysiology.
In particular, alterations in genes associated
with response to stress, apoptosis, ion channel
activity, and neuronal and
synaptic modeling were observed.
We are particularly interested in an emotional stress - induced change in endocannabinoid signaling and
synaptic transmission and the effects of stress on the
activity of a neuronal circuitthat is associated
with learning / memory (see J. Neurosci.31: 501, 2011, 29:381, 2009; Nature Neurosci.
Advances in optical imaging and optogenetics combined
with electrophysiological recordings enable Albeanu and colleagues to monitor and / or alter patterns of
activity at unprecedented
synaptic and millisecond resolution, in real time, as animals are engaged in various behaviors.
«Without this specialized neurotransmitter recycling and endocytosis,
synaptic vesicles are not recycled fast enough to keep up
with nerve and muscle cell
activity,» she said.
The simultaneous EEG and fMRI recordings allowed us to explore how theta power fluctuations driven by the movie correlate
with local
synaptic activity in auditory cortex, as indexed by the BOLD signal (Magri et al., 2012; see Materials and Methods).
When soy lecithin supplements were given throughout perinatal development, they reduced
activity in the cerebral cortex and «altered
synaptic characteristics in a manner consistent
with disturbances in neural function.»
In fact, overactive
synaptic activity has been associated
with diseases like Parkinson's, Alzheimer's, and other degenerative diseases.