Sentences with phrase «with therapeutic agents»

Most industry experts agree that personalized medicine and theranostics — diagnostic tests bundled with therapeutic agents to treat a specific disease — point to a bright future for the industry.

When the institute tried injecting Ebola - infected animals — first guinea pigs, then monkeys — with its therapeutic agent encased in the lipid nanoparticles, the survival rate rose to 100 %, from around 20 % in previous trials.

Surprisingly, if TOR's activity is acutely inhibited by treatment with the therapeutic agent Rapamycin, sleep quality improves even in old flies, suggesting that age - related sleep decline is not only preventable, but also reversible.

Not exact matches

Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis disease or are human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear of lesions).

Structure - based drug design, in which the physical structure of a targeted protein is used to help identify compounds that will interact with it, has already been used to generate therapeutic agents for a number of infectious and metabolic diseases.

Inducing therapeutic ketosis solely with the ketogenic diet can be difficult, however, so the USF researchers created novel metabolic agents that induce ketosis without dietary restriction.

Clinicians are currently worried that breast cancer patients with low or absent BRCA1 may become resistant to therapeutic agents such as Olaparib.

Gad Berdugo, CEO of EpiVax Oncology, says that such therapeutic vaccines could be used in combination with checkpoint inhibitors or, potentially, as single agents.

Multicomponent reactions are protocols that ease the chemical synthesis of new compounds, and are particularly important to gain molecules with biological activity as therapeutic agents against several pathogens.

The cancer researchers also found that PAK is still active, when cancer cells have already been treated with the current standard therapeutic agent Imatinib.

UTMD uses microscopic, gas - filled bubbles that can be paired with viral therapies, therapeutic genes and proteins, and imaging agents.

We review progress with the receptor tyrosine kinases (growth factor receptors EGFR, VEGFR, and FGFR) and nonreceptor tyrosine kinases (Bcr - Abl), where advances have been made with cancer therapeutic agents such as Herceptin and Gleevec.

While the study did not support earlier findings that sitagliptin was an effective treatment for NAFLD, Loomba said it provided new evidence that clinical trials with patients at higher risk of diabetes do not necessarily need a liver biopsy to be efficiently screened for potential therapeutic agents.

These results could pave the way for the use of progesterone against glioblastoma in a human clinical trial, perhaps in combination with standard - of - care therapeutic agents such as temozolomide.

• Pharmacogenetics The unit offers population screening for a number of validated polymorphisms with pharmacogenetic implications, associated with positive or negative responses to therapeutic agents.

Characterized as a biological subset of PTCL - NOS, patients with dysregulation of the histone modification machinery may be amenable to therapeutic intervention with HDAC inhibitors, given either alone or in combination with hypomethylating agents.

Our group has 3 major goals: Develop novel therapeutic approaches based on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple myeloma

«Collaborating with the outstanding scientists at Lundbeck, offers great hope for discovering what triggers these diseases and developing novel therapeutic agents.»

«We are very excited to collaborate with the team at Novo Biosciences on this very promising therapeutic agent for the treatment of heart failure,» said Lefer.

In addition, we have access to new agent trials through the Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) consortium, and we offer CAR T - cell therapy for eligible children with relapsed or refractory acute lymphoblastic leukemia (ALL).

Early data from a small phase Ib / II study [23] of ipilimumab combined with T - VEC, which demonstrated that the combination offers much higher complete and overall response rates than have been seen with either agent alone, appear to confirm that there are beneficial synergies between these two therapeutic modalities.

Your approach with these agents should be to gradually titrate the dose upward to a high therapeutic level, then back it down.

«Free - ranging chickens can be treated with therapeutic antibiotics under veterinary direction and sold with the use of coccidiostats [a chemical agent added to animal feed]», says Sally, author of Eat Yourself Healthy in 28 Days...»

It is also anti-inflammatory in nature and hence is a therapeutic agent for prevention of several diseases associated with inflammation.

Therapeutic diets replace the «agents of disease» with real food which enables the body to regulate and restore itself.

Details regarding the nature of these pathways are still being investigated, although interventions targeting these mechanisms have therapeutic potential, as already seen with thiazolidinediones, agents that increase insulin sensitivity and decrease muscle and hepatic triglyceride load (16).

Revaccination: Annual revaccination with a single dose is recommended, although, as recommended by the American Veterinary Medical Association and its Council on Biologic and Therapeutic Agents, the attending veterinarian should determine the frequency of revaccination based on the animal's lifestyle and risk of exposure.

The therapeutic milieu is a primary agent for change with youth.

In addition, many children with juvenile arthritis experience prolonged periods of low levels of disease activity or even complete remission due to the development of new therapeutic agents (Ravelli & Martini, 2006).

I especially believe in the importance of the therapeutic alliance as the primary healing agent and work to maintain a safe and supportive relationship with you in a professional environment.

Because research shows promising evidence that relational agents can establish a therapeutic relationship with patients and that they are accepted by a wide variety of patient populations [18,19], relational agents have the potential to enhance reach and public health impact of efficacious interventions by overcoming limitations associated with face - to - face delivery.