Sentences with phrase «with transgenic»

Mice were generated with the Transgenic Mouse Core of the Penn Diabetes Research Center (DK19525).

Through the use of mice with transgenic expression of CD1a, we...

METHODS: Gene gun immunization is conducted with transgenic mice using the Abeta42 gene in a bacterial plasmid with the pSP72 - E3L - Abeta42 construct.

That's easier with some transgenic proteins than others.

As the level of gene activity knockdown associated with transgenic RNAi depends on the level of expression of the hairpin constructs, we generated a number of derivatives of our initial vector, called the «VALIUM» series, to improve the efficiency of the method.

Mice with a transgenic copy of the human SMN2 gene lose approximately 20 percent of their anterior horn cells, are extremely weakand underweight, and display other manifestations of disease, as well as die after two weeks.

To test their reasoning they conducted a second experiment by crossing mice carrying the prostate - specific IGF - 1R knockout alleles with transgenic mice that develop spontaneous prostate cancer when p53 and select other genes are compromised.

We have replaced the tobacco RbcL gene with transgenic loci containing two or three cyanobacterial genes encoding the S. elongatus Rubisco large subunit (Se LS), small subunit (Se SS) either alone or with the putative chaperone RbcX or a gene encoding the carboxysomal protein M35.

Applications for permission to work with transgenic livestock, for example, are piling up at the US Department of Agriculture while the administration decides which agency should handle regulation of this technology.

Additional experiments with transgenic mice indicated that L1 had hopscotched in a subset of brain cells, but not in the cells of most other tissues.

The role of these different forms was explored with transgenic mice expressing PrP mutations that alter the relative ratios of the topological forms.

In order to visualize this signal, the scientists performed experiments with transgenic Arabidopsis plants which were genetically modified to express a protein in the cytosol, the liquid inside the cells, which breaks down and releases light energy after it has bound calcium ions.

They bred this mouse with another transgenic mouse that carries a piece of DNA that recognises vasa and changes the colour of only those cells that carry it.

He gave me the opportunity to work with transgenic plants, specifically to assess cold and frost tolerance of transgenic canola.

Eventually these trees will be cross-pollinated with transgenic, blight - resistant American Chestnut seeds, which will produce blight resistant seeds that the Parks Department can then reproduce.

High has experimented with transgenics in a number of multimedia, interspecies projects such as Embracing Animal (2004 - 2006), and she has staged competitions between human white blood cells through her ongoing Blood Wars tournaments.

Not exact matches

Using genetic engineering or transgenic technology, the DNA of plants and animals is combined with the DNA of other species and artificially modified to exhibit traits such as resistance to cold or herbicides.

Thanks to CRISPR gene - editing tools, researchers can tweak the rat genome to create so - called transgenic animals with human - like disease traits.

Twelve transgenic piglets endowed with a mouse UCP1 gene were better able to maintain their body temperature than their unmodified counterparts when they were exposed to cold for a 4 - hour period, the authors report today in the Proceedings of the National Academy of Sciences.

«Until everyone embraces transgenics — which, personally, I've been working on these things for over 20 years, and I don't see any problem with using biotechnology — we are also exploring alternatives,» says Arias.

A transgenic mouse — one with foreign genes swapped into its DNA — poses with its own gene sequence at Harvard Medical School.

Transgenic mice were created with cardiac - specific overexpression of the beta 2 - adrenergic receptor.

This resulted in increased basal myocardial adenylyl cyclase activity, enhanced atrial contractility, and increased left ventricular function in vivo; these parameters at baseline in the transgenic animals were equal to those observed in control animals maximally stimulated with isoproterenol.

But transgenic mice with the codon - 127 mutation were completely resistant to kuru and CJD regardless of whether they bore one or two copies of it.

A few years after he arrived in Carbondale to run SIU's physiology department, he began collaborating with Thomas Wagner, a geneticist at Ohio University in Athens who was a pioneer in engineering transgenic animals.

Transgenic plants are plants that have been genetically engineered, a breeding approach that uses recombinant DNA techniques to create plants with new characteristics.They are identified as a class of genetically modified organism (GMO).

Dolly the sheep was cloned, in fact, with the intention of eventually using this procedure to create transgenic animals having useful properties, not as a means to make carbon copies of baseball legend Ted Williams or a favorite dead pet.

Goats as Drug Factories Initially, GTC generated transgenic goats by microinjecting into the developing nucleus of a one - cell embryo a gene encoding the desired human protein (along with DNA that promotes activation of that gene in milk).

The idea of making transgenic drugs occurred to a number of scientists during the mid-1980s, when the new industry began to wrestle with the challenge of making complex proteins: ensuring that these big molecules were folded into the proper shape and that they had all their sugars in the right places on the surface of the proteins» amino acids.

In mid-2001 Nusinoff Lehrman left, and her replacement, Geoffrey Cox, decided to proceed with development of transgenic antithrombin — this time in European clinical trials for patients with inherited antithrombin deficiency.

Their plan is to make a transgenic chestnut with genes that inhibit the growth of the fungus.

Pedro Sanchez says we need nanofertilizers, transgenic crops, and governments and investors with cojones.

The mature transgenic animals were bred usually with nontransgenic goats as a first step toward producing a herd.

Engineered organisms that can not breed with wild counterparts could prevent transgenic plants from spreading genes

Although the bulk of the commercial manufacturing uses cultures of bacteria, such as Escherichia coli or Chinese hamster ovary cells, a few biotech companies are trying to produce therapeutic proteins in the milk of transgenic mammals (such as GTC Biotherapeutics, which is using goats; PPL Therapeutics, which is using sheep; and BioProtein Technologies, which is working with rabbits), transgenic chicken eggs (such as Avigenics or Vivalis), or even in transgenic crops (such as ProdiGene or Meristem Therapeutics); but it is early days for these «pharming» methods.

Scientists are creating transgenic mosquitoes with reduced ability to carry the devastating diseases that have plagued much of humanity.

FUS3pro:: WRI1: seed of the transgenic plant with extended oil synthesis phase during seed formation.

The leaves were taken from transplastomic dsRNA plants, conventional transgenic dsRNA plants with a modified nuclear genome, and unmodified plants.

FUS3pro:: WRI1 / 12s1.4: seed of the transgenic plant with extended oil synthesis phase and disrupted formation of major seed storage proteins.

For this study, they created several lines of transgenic Brazilian and African rice that overexpress this gene, and with their CIAT and JIRCAS collaborators, tested how well the rice grew in different conditions in different years.

Here are the 20 finalists from the 2007 contest, starting with the winning picture: a 17 - times magnified view of a double - transgenic mouse embryo by Gloria Kwon of the Memorial - Sloan Kettering Institute in New York.

This yielded transgenic cassavas with 60 % to 94 % less linamarin in their leaves.

Preliminary tests indicate that transgenic plants are somewhat stunted for a month if not fertilized with soil ammonia.

Such claims have linked the rise in occurrence of corn diseases like Goss's wilt, which causes leaf blight and systemic wilt, to the adoption of transgenic corn across the U.S.. However, a new study from the USDA - Agricultural Research Service (ARS) provides empirical evidence showing no increase in disease susceptibility in transgenic sweet corn treated with glyphosate.

Experiment showed transgenic sweet corn was not more susceptible to Goss's wilt disease when treated with glyphosate.

Now, geneticists have developed a potential boon for the health of African subsistence farmers who rely on the crop: transgenic plants with roots practically free of cyanide - forming chemicals.

As they grew, the transgenic finches all began to display the behavior disorders associated with Huntington's, such as tremors sometimes seen in patients.

The new study is the first demonstration of an approach combining ancestral sequence reconstruction with the making of transgenic organisms to directly test hypotheses at multiple biological levels, Siddiq said.

It's a broadly applicable approach that in theory could be used with other organisms that lend themselves to transgenic engineering.

Without access to transgenic mice, Castro says he's «competing at a disadvantage» with mainland Spain.